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[Pathogen spectrum and correlative factors of nosocomial infection in patients with lung cancer].
Zhongguo Fei Ai Za Zhi 2005; 8(5):468-71ZF

Abstract

BACKGROUND

Lung cancer is one of the most common malignant tumors in China. Surgical resection is still the first choice of treatment for most lung cancer patients. The prognosis of lung cancer after surgical treatment is correlated to many factors. One of them is nosocomial infection. This study is to investigate the distribution of the pathogens causing nosocomial infection and its correlative factors in patients with lung cancer.

METHODS

One hundred and thirteen cases that had hospital-acquired infection out of 1227 surgically treated patients with lung cancer were analyzed statistically.

RESULTS

Of all the pathogenic species, the most prevalent species were Gram-negative bacteria with average positive detection of 64.03% (299/467). The second were Gram-positive bacteria (145/467, 31.05%) and the third were fungi (23/467, 4.92%). The results of drug sensitivity tests showed that all of strains had higher resistance rate. The rate of extended spectrum β-lactamases (ESBLs) and meticillin-resistant Staphylococcus (MRS) was very high. The incidence of nosocomial infection was seriously correlated with age, fatness, long smoking history, complicated diseases such as diabetes, damaged renal function and using time of mechanical ventilation over 24 hours.

CONCLUSIONS

The nosocomial infection of lung cancer patients after surgical treatment is seriously correlated with patient's age, fatness, long smoking history, complicated diseases such as diabetes, damaged renal function and using time of mechanical ventilation over 24 hours. More attentions should be paid to the pathogenic species and its correlative factors of nosocomial infection in lung cancer patients. The resistance of bacteria to the commonly used antibiotics is produced in various degrees. During clinical therapy with antibiotics, antibiotics should be selected according to the results of drug sensitivity tests. In order to reduce the production of drug-resistance, the appropriate use of antibiotics must be strengthened.

Authors+Show Affiliations

Department of Cardiothoracic Surgery, Tongji Hospital, Tongji Medical College of HUST, Wuhan, Hubei 430030, P.R.China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

21205537

Citation

Pan, Youmin, et al. "[Pathogen Spectrum and Correlative Factors of Nosocomial Infection in Patients With Lung Cancer]." Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer, vol. 8, no. 5, 2005, pp. 468-71.
Pan Y, Pan T, Tang Y, et al. [Pathogen spectrum and correlative factors of nosocomial infection in patients with lung cancer]. Zhongguo Fei Ai Za Zhi. 2005;8(5):468-71.
Pan, Y., Pan, T., Tang, Y., Shen, Z., & Zheng, Z. (2005). [Pathogen spectrum and correlative factors of nosocomial infection in patients with lung cancer]. Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer, 8(5), pp. 468-71. doi:10.3779/j.issn.1009-3419.2005.05.26.
Pan Y, et al. [Pathogen Spectrum and Correlative Factors of Nosocomial Infection in Patients With Lung Cancer]. Zhongguo Fei Ai Za Zhi. 2005 Oct 20;8(5):468-71. PubMed PMID: 21205537.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Pathogen spectrum and correlative factors of nosocomial infection in patients with lung cancer]. AU - Pan,Youmin, AU - Pan,Tiecheng, AU - Tang,Yingxiong, AU - Shen,Zhengyi, AU - Zheng,Zhi, PY - 2011/1/6/entrez PY - 2005/10/20/pubmed PY - 2005/10/20/medline SP - 468 EP - 71 JF - Zhongguo fei ai za zhi = Chinese journal of lung cancer JO - Zhongguo Fei Ai Za Zhi VL - 8 IS - 5 N2 - BACKGROUND: Lung cancer is one of the most common malignant tumors in China. Surgical resection is still the first choice of treatment for most lung cancer patients. The prognosis of lung cancer after surgical treatment is correlated to many factors. One of them is nosocomial infection. This study is to investigate the distribution of the pathogens causing nosocomial infection and its correlative factors in patients with lung cancer. METHODS: One hundred and thirteen cases that had hospital-acquired infection out of 1227 surgically treated patients with lung cancer were analyzed statistically. RESULTS: Of all the pathogenic species, the most prevalent species were Gram-negative bacteria with average positive detection of 64.03% (299/467). The second were Gram-positive bacteria (145/467, 31.05%) and the third were fungi (23/467, 4.92%). The results of drug sensitivity tests showed that all of strains had higher resistance rate. The rate of extended spectrum β-lactamases (ESBLs) and meticillin-resistant Staphylococcus (MRS) was very high. The incidence of nosocomial infection was seriously correlated with age, fatness, long smoking history, complicated diseases such as diabetes, damaged renal function and using time of mechanical ventilation over 24 hours. CONCLUSIONS: The nosocomial infection of lung cancer patients after surgical treatment is seriously correlated with patient's age, fatness, long smoking history, complicated diseases such as diabetes, damaged renal function and using time of mechanical ventilation over 24 hours. More attentions should be paid to the pathogenic species and its correlative factors of nosocomial infection in lung cancer patients. The resistance of bacteria to the commonly used antibiotics is produced in various degrees. During clinical therapy with antibiotics, antibiotics should be selected according to the results of drug sensitivity tests. In order to reduce the production of drug-resistance, the appropriate use of antibiotics must be strengthened. SN - 1009-3419 UR - https://www.unboundmedicine.com/medline/citation/21205537/[Pathogen_spectrum_and_correlative_factors_of_nosocomial_infection_in_patients_with_lung_cancer]_ L2 - https://doi.org/10.3779/j.issn.1009-3419.2005.05.26 DB - PRIME DP - Unbound Medicine ER -