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A new dimeric resveratrol from the roots of Shorea roxburghii.
Fitoterapia. 2011 Apr; 82(3):489-92.F

Abstract

A new resveratrol dimer, roxburghiol A (1) together with eleven known compounds were isolated from the roots of Shorea roxburghii. Their structures were identified on the basis of spectroscopic evidence and physicochemical properties. All isolated compounds were evaluated for their cytotoxicity (KB and HeLa cells). Compounds 8 and 9 showed potent cytotoxicity against both KB and HeLa cell lines with IC(50) values of 6.5, 8.5 and 8.7, 10.1 μg/mL, respectively.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Patcharamun W
Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Sichaem J
No affiliation info available
Siripong P
No affiliation info available
Khumkratok S
No affiliation info available
Jong-aramruang J
No affiliation info available
Tip-pyang S
No affiliation info available

MeSH

Antineoplastic Agents, PhytogenicDipterocarpaceaeHeLa CellsHumansInhibitory Concentration 50KB CellsMolecular StructureNeoplasmsPhytotherapyPlant ExtractsPlant RootsStilbenes

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21238549

Citation

Patcharamun, Winitra, et al. "A New Dimeric Resveratrol From the Roots of Shorea Roxburghii." Fitoterapia, vol. 82, no. 3, 2011, pp. 489-92.
Patcharamun W, Sichaem J, Siripong P, et al. A new dimeric resveratrol from the roots of Shorea roxburghii. Fitoterapia. 2011;82(3):489-92.
Patcharamun, W., Sichaem, J., Siripong, P., Khumkratok, S., Jong-aramruang, J., & Tip-pyang, S. (2011). A new dimeric resveratrol from the roots of Shorea roxburghii. Fitoterapia, 82(3), 489-92. https://doi.org/10.1016/j.fitote.2011.01.003
Patcharamun W, et al. A New Dimeric Resveratrol From the Roots of Shorea Roxburghii. Fitoterapia. 2011;82(3):489-92. PubMed PMID: 21238549.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new dimeric resveratrol from the roots of Shorea roxburghii. AU - Patcharamun,Winitra, AU - Sichaem,Jirapast, AU - Siripong,Pongpan, AU - Khumkratok,Suttira, AU - Jong-aramruang,Jonkolnee, AU - Tip-pyang,Santi, Y1 - 2011/01/14/ PY - 2010/10/15/received PY - 2010/12/31/revised PY - 2011/01/05/accepted PY - 2011/1/18/entrez PY - 2011/1/18/pubmed PY - 2011/9/7/medline SP - 489 EP - 92 JF - Fitoterapia JO - Fitoterapia VL - 82 IS - 3 N2 - A new resveratrol dimer, roxburghiol A (1) together with eleven known compounds were isolated from the roots of Shorea roxburghii. Their structures were identified on the basis of spectroscopic evidence and physicochemical properties. All isolated compounds were evaluated for their cytotoxicity (KB and HeLa cells). Compounds 8 and 9 showed potent cytotoxicity against both KB and HeLa cell lines with IC(50) values of 6.5, 8.5 and 8.7, 10.1 μg/mL, respectively. SN - 1873-6971 UR - https://www.unboundmedicine.com/medline/citation/21238549/A_new_dimeric_resveratrol_from_the_roots_of_Shorea_roxburghii_ DB - PRIME DP - Unbound Medicine ER -