Tags

Type your tag names separated by a space and hit enter

A review of the relationships between Landau-Kleffner syndrome, electrical status epilepticus during sleep, and continuous spike-waves during sleep.
Epilepsy Behav. 2011 Feb; 20(2):247-53.EB

Abstract

The goal of this report is to review the relationships between Landau-Kleffner syndrome (LKS), electrical status epilepticus during sleep (ESES), and continuous spike-waves during sleep (CSWS). LKS is a clinical syndrome involving mainly acquired aphasia and sometimes seizures. Other clinical findings include cognitive impairments and global regression of behavior. The EEG may evolve from more benign conditions into ESES (or CSWS), seen in 50% of patients with LKS, or may also show focal findings. Seizures include atypical absence, generalized tonic-clonic, atonic, and partial motor attacks. Effective medications are discussed. The EEG patterns CSWS and ESES are likely equivalent terms. CSWS is used by some authors, and ESES by others. Patients with these patterns usually show mental retardation, seizures, and global regression. More benign EEG patterns, like focal discharges, may develop into these more severe generalized patterns, which are associated with atypical absences, negative myoclonus, and cognitive disturbances. Memory disorders are common, because the nearly continuous generalized discharges in sleep do not allow for the memory consolidation that also occurs during sleep. Medications and possible etiologies are discussed.

Authors+Show Affiliations

Department of Neurology, University of Illinois Medical Center at Chicago, Chicago, IL 60612, USA. jhughes@uic.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21242107

Citation

Hughes, John R.. "A Review of the Relationships Between Landau-Kleffner Syndrome, Electrical Status Epilepticus During Sleep, and Continuous Spike-waves During Sleep." Epilepsy & Behavior : E&B, vol. 20, no. 2, 2011, pp. 247-53.
Hughes JR. A review of the relationships between Landau-Kleffner syndrome, electrical status epilepticus during sleep, and continuous spike-waves during sleep. Epilepsy Behav. 2011;20(2):247-53.
Hughes, J. R. (2011). A review of the relationships between Landau-Kleffner syndrome, electrical status epilepticus during sleep, and continuous spike-waves during sleep. Epilepsy & Behavior : E&B, 20(2), 247-53. https://doi.org/10.1016/j.yebeh.2010.10.015
Hughes JR. A Review of the Relationships Between Landau-Kleffner Syndrome, Electrical Status Epilepticus During Sleep, and Continuous Spike-waves During Sleep. Epilepsy Behav. 2011;20(2):247-53. PubMed PMID: 21242107.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A review of the relationships between Landau-Kleffner syndrome, electrical status epilepticus during sleep, and continuous spike-waves during sleep. A1 - Hughes,John R, Y1 - 2011/01/15/ PY - 2010/08/24/received PY - 2010/10/14/revised PY - 2010/10/14/accepted PY - 2011/1/19/entrez PY - 2011/1/19/pubmed PY - 2011/6/15/medline SP - 247 EP - 53 JF - Epilepsy & behavior : E&B JO - Epilepsy Behav VL - 20 IS - 2 N2 - The goal of this report is to review the relationships between Landau-Kleffner syndrome (LKS), electrical status epilepticus during sleep (ESES), and continuous spike-waves during sleep (CSWS). LKS is a clinical syndrome involving mainly acquired aphasia and sometimes seizures. Other clinical findings include cognitive impairments and global regression of behavior. The EEG may evolve from more benign conditions into ESES (or CSWS), seen in 50% of patients with LKS, or may also show focal findings. Seizures include atypical absence, generalized tonic-clonic, atonic, and partial motor attacks. Effective medications are discussed. The EEG patterns CSWS and ESES are likely equivalent terms. CSWS is used by some authors, and ESES by others. Patients with these patterns usually show mental retardation, seizures, and global regression. More benign EEG patterns, like focal discharges, may develop into these more severe generalized patterns, which are associated with atypical absences, negative myoclonus, and cognitive disturbances. Memory disorders are common, because the nearly continuous generalized discharges in sleep do not allow for the memory consolidation that also occurs during sleep. Medications and possible etiologies are discussed. SN - 1525-5069 UR - https://www.unboundmedicine.com/medline/citation/21242107/A_review_of_the_relationships_between_Landau_Kleffner_syndrome_electrical_status_epilepticus_during_sleep_and_continuous_spike_waves_during_sleep_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1525-5050(10)00662-1 DB - PRIME DP - Unbound Medicine ER -