Tags

Type your tag names separated by a space and hit enter

Assessment of association between low back pain and paraspinal muscle atrophy using opposed-phase magnetic resonance imaging: a population-based study among young adults.
Spine (Phila Pa 1976). 2011 Nov 01; 36(23):1961-8.S

Abstract

STUDY DESIGN

A cross-sectional imaging study of young adults.

OBJECTIVE

To evaluate whether severity of low back symptoms predicts atrophy in the paraspinal muscles of young adults.

SUMMARY OF BACKGROUND DATA

Although an increased fat content of the lumbar muscles has been observed among adults with chronic LBP, there is limited knowledge of this association in younger populations.

METHODS

The population-based study sample consisted of 554 subjects (321 females and 233 males) from the 1986 Northern Finland Birth Cohort. Latent Class Analysis (LCA) was used to cluster the subjects according to the low back symptoms and functional limitations at 18, 19, and 21 years. The mean age of the subjects at the time of the MRI (magnetic resonance imaging) was 21 years (range, 20-23). Muscle atrophy was evaluated by assessing the fat content of the paraspinal muscles using Opposed-Phase MRI. The cross-sectional areas (CSAs) of the erector spinae and multifidus muscles were also measured.

RESULTS

LCA analysis produced five clusters differing in symptoms, ranging from a cluster (n = 65) in which subjects had high likelihood of symptoms and functional limitations at all time points, to a cluster (n = 165) with no pain ever. The fat content of the multifidus muscles was significantly higher among women than men (14.0% vs. 5.3%, P < 0.001), but it was not significantly associated with symptom severity. The CSA of both erector spinae and multifidus muscles were significantly larger among men than women (P < 0.001 in all of the muscles), but were not associated with pain severity.

CONCLUSION

Low back symptoms and functional limitations over a 3-year period were not associated with increased fat content or a reduction in the cross-sectional area of lumbar paraspinal muscles among young adults.

Authors+Show Affiliations

Department of Physical and Rehabilitation Medicine, Institute of Clinical Medicine, University of Oulu, Oulu, Finland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21289551

Citation

Paalanne, Niko, et al. "Assessment of Association Between Low Back Pain and Paraspinal Muscle Atrophy Using Opposed-phase Magnetic Resonance Imaging: a Population-based Study Among Young Adults." Spine, vol. 36, no. 23, 2011, pp. 1961-8.
Paalanne N, Niinimäki J, Karppinen J, et al. Assessment of association between low back pain and paraspinal muscle atrophy using opposed-phase magnetic resonance imaging: a population-based study among young adults. Spine. 2011;36(23):1961-8.
Paalanne, N., Niinimäki, J., Karppinen, J., Taimela, S., Mutanen, P., Takatalo, J., Korpelainen, R., & Tervonen, O. (2011). Assessment of association between low back pain and paraspinal muscle atrophy using opposed-phase magnetic resonance imaging: a population-based study among young adults. Spine, 36(23), 1961-8. https://doi.org/10.1097/BRS.0b013e3181fef890
Paalanne N, et al. Assessment of Association Between Low Back Pain and Paraspinal Muscle Atrophy Using Opposed-phase Magnetic Resonance Imaging: a Population-based Study Among Young Adults. Spine. 2011 Nov 1;36(23):1961-8. PubMed PMID: 21289551.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Assessment of association between low back pain and paraspinal muscle atrophy using opposed-phase magnetic resonance imaging: a population-based study among young adults. AU - Paalanne,Niko, AU - Niinimäki,Jaakko, AU - Karppinen,Jaro, AU - Taimela,Simo, AU - Mutanen,Pertti, AU - Takatalo,Jani, AU - Korpelainen,Raija, AU - Tervonen,Osmo, PY - 2011/2/4/entrez PY - 2011/2/4/pubmed PY - 2012/6/2/medline SP - 1961 EP - 8 JF - Spine JO - Spine VL - 36 IS - 23 N2 - STUDY DESIGN: A cross-sectional imaging study of young adults. OBJECTIVE: To evaluate whether severity of low back symptoms predicts atrophy in the paraspinal muscles of young adults. SUMMARY OF BACKGROUND DATA: Although an increased fat content of the lumbar muscles has been observed among adults with chronic LBP, there is limited knowledge of this association in younger populations. METHODS: The population-based study sample consisted of 554 subjects (321 females and 233 males) from the 1986 Northern Finland Birth Cohort. Latent Class Analysis (LCA) was used to cluster the subjects according to the low back symptoms and functional limitations at 18, 19, and 21 years. The mean age of the subjects at the time of the MRI (magnetic resonance imaging) was 21 years (range, 20-23). Muscle atrophy was evaluated by assessing the fat content of the paraspinal muscles using Opposed-Phase MRI. The cross-sectional areas (CSAs) of the erector spinae and multifidus muscles were also measured. RESULTS: LCA analysis produced five clusters differing in symptoms, ranging from a cluster (n = 65) in which subjects had high likelihood of symptoms and functional limitations at all time points, to a cluster (n = 165) with no pain ever. The fat content of the multifidus muscles was significantly higher among women than men (14.0% vs. 5.3%, P < 0.001), but it was not significantly associated with symptom severity. The CSA of both erector spinae and multifidus muscles were significantly larger among men than women (P < 0.001 in all of the muscles), but were not associated with pain severity. CONCLUSION: Low back symptoms and functional limitations over a 3-year period were not associated with increased fat content or a reduction in the cross-sectional area of lumbar paraspinal muscles among young adults. SN - 1528-1159 UR - https://www.unboundmedicine.com/medline/citation/21289551/Assessment_of_association_between_low_back_pain_and_paraspinal_muscle_atrophy_using_opposed_phase_magnetic_resonance_imaging:_a_population_based_study_among_young_adults_ L2 - http://dx.doi.org/10.1097/BRS.0b013e3181fef890 DB - PRIME DP - Unbound Medicine ER -