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Intradural cervical disc herniation: report of two cases and review of the literature.
Spine (Phila Pa 1976). 2011 Jul 01; 36(15):E1033-7.S

Abstract

STUDY DESIGN

Case report and review of the literature.

OBJECTIVE

To report two additional cases with intradural cervical herniation and review the pertinent literature.

SUMMARY OF BACKGROUND DATA

Intradural cervical disc herniation is rare and a total of 22 cases were reported in 2007. In searching the world literature on this topic, we found 27 cases of intradural cervical disc herniation in all.

METHODS

Clinical history, physical examination, and radiographic findings of two patients with intradural cervical disc herniation were described, and corpectomy was performed in both cases. A review of the literature was completed.

RESULT

The outcome of one case was gratifying, and at a 36-month follow-up, nearly a full recovery was obtained. But the other's condition was disappointing, whose postoperative MRI demonstrated high signal intensity in the spinal cord and adhesion of spinal cord to the posterior margin at C4 level.

CONCLUSION

Intradural cervical disc herniation is relatively rare, and the two additional cases updated the number of this condition to 29. It remains difficult to definitively diagnose the disease before surgery, but some indirect signs may indicate the cases. Corpectomy under a microscope as the first option in treatment of this disease is recommended once it is highly diagnosed. The pathogenesis of intradural cervical disc herniation remains to be further investigated. We presume that biochemical factors may play an important role in the pathogenesis.

Authors+Show Affiliations

Orthopedic & Trauma-Surgery Department, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

21289557

Citation

Pan, Jie, et al. "Intradural Cervical Disc Herniation: Report of Two Cases and Review of the Literature." Spine, vol. 36, no. 15, 2011, pp. E1033-7.
Pan J, Li L, Qian L, et al. Intradural cervical disc herniation: report of two cases and review of the literature. Spine. 2011;36(15):E1033-7.
Pan, J., Li, L., Qian, L., Teng, H., Shen, B., Tan, J., Zhou, W., & Yang, M. (2011). Intradural cervical disc herniation: report of two cases and review of the literature. Spine, 36(15), E1033-7. https://doi.org/10.1097/BRS.0b013e3181fee8d2
Pan J, et al. Intradural Cervical Disc Herniation: Report of Two Cases and Review of the Literature. Spine. 2011 Jul 1;36(15):E1033-7. PubMed PMID: 21289557.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intradural cervical disc herniation: report of two cases and review of the literature. AU - Pan,Jie, AU - Li,Lijun, AU - Qian,Lie, AU - Teng,Honglin, AU - Shen,Bin, AU - Tan,Jun, AU - Zhou,Wei, AU - Yang,Mingjie, PY - 2011/2/4/entrez PY - 2011/2/4/pubmed PY - 2011/12/15/medline SP - E1033 EP - 7 JF - Spine JO - Spine VL - 36 IS - 15 N2 - STUDY DESIGN: Case report and review of the literature. OBJECTIVE: To report two additional cases with intradural cervical herniation and review the pertinent literature. SUMMARY OF BACKGROUND DATA: Intradural cervical disc herniation is rare and a total of 22 cases were reported in 2007. In searching the world literature on this topic, we found 27 cases of intradural cervical disc herniation in all. METHODS: Clinical history, physical examination, and radiographic findings of two patients with intradural cervical disc herniation were described, and corpectomy was performed in both cases. A review of the literature was completed. RESULT: The outcome of one case was gratifying, and at a 36-month follow-up, nearly a full recovery was obtained. But the other's condition was disappointing, whose postoperative MRI demonstrated high signal intensity in the spinal cord and adhesion of spinal cord to the posterior margin at C4 level. CONCLUSION: Intradural cervical disc herniation is relatively rare, and the two additional cases updated the number of this condition to 29. It remains difficult to definitively diagnose the disease before surgery, but some indirect signs may indicate the cases. Corpectomy under a microscope as the first option in treatment of this disease is recommended once it is highly diagnosed. The pathogenesis of intradural cervical disc herniation remains to be further investigated. We presume that biochemical factors may play an important role in the pathogenesis. SN - 1528-1159 UR - https://www.unboundmedicine.com/medline/citation/21289557/Intradural_cervical_disc_herniation:_report_of_two_cases_and_review_of_the_literature_ L2 - http://dx.doi.org/10.1097/BRS.0b013e3181fee8d2 DB - PRIME DP - Unbound Medicine ER -