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No effect of 2008/09 seasonal influenza vaccination on the risk of pandemic H1N1 2009 influenza infection in England.
Vaccine 2011; 29(14):2613-8V

Abstract

This study reports effectiveness of trivalent influenza vaccine (TIV) against confirmed pandemic influenza infection in England using a retrospective test-negative case-control study. Cases and controls were frequency matched by age, swabbing-week and region. On univariable and multivariable analysis adjusted for underlying clinical risk factors, cases were no more or less likely than controls to be vaccinated with 2008-09 or 2007-08 season TIV. Adjusted vaccine effectiveness for the former was -6% (-43% to 22%). Vaccine effectiveness did not differ significantly by age-group or hospitalisation status. There was no evidence prior vaccination with TIV significantly altered subsequent risk of pandemic influenza H1N1 2009 infection.

Authors+Show Affiliations

Health Protection Agency Centre for Infections, 61 Colindale Avenue, UK. Richard.Pebody@hpa.org.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21292008

Citation

Pebody, Richard, et al. "No Effect of 2008/09 Seasonal Influenza Vaccination On the Risk of Pandemic H1N1 2009 Influenza Infection in England." Vaccine, vol. 29, no. 14, 2011, pp. 2613-8.
Pebody R, Andrews N, Waight P, et al. No effect of 2008/09 seasonal influenza vaccination on the risk of pandemic H1N1 2009 influenza infection in England. Vaccine. 2011;29(14):2613-8.
Pebody, R., Andrews, N., Waight, P., Malkani, R., McCartney, C., Ellis, J., & Miller, E. (2011). No effect of 2008/09 seasonal influenza vaccination on the risk of pandemic H1N1 2009 influenza infection in England. Vaccine, 29(14), pp. 2613-8. doi:10.1016/j.vaccine.2011.01.046.
Pebody R, et al. No Effect of 2008/09 Seasonal Influenza Vaccination On the Risk of Pandemic H1N1 2009 Influenza Infection in England. Vaccine. 2011 Mar 21;29(14):2613-8. PubMed PMID: 21292008.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - No effect of 2008/09 seasonal influenza vaccination on the risk of pandemic H1N1 2009 influenza infection in England. AU - Pebody,Richard, AU - Andrews,Nick, AU - Waight,Pauline, AU - Malkani,Rashmi, AU - McCartney,Christine, AU - Ellis,Joanna, AU - Miller,Elizabeth, Y1 - 2011/02/01/ PY - 2010/04/01/received PY - 2010/12/30/revised PY - 2011/01/18/accepted PY - 2011/2/5/entrez PY - 2011/2/5/pubmed PY - 2011/6/15/medline SP - 2613 EP - 8 JF - Vaccine JO - Vaccine VL - 29 IS - 14 N2 - This study reports effectiveness of trivalent influenza vaccine (TIV) against confirmed pandemic influenza infection in England using a retrospective test-negative case-control study. Cases and controls were frequency matched by age, swabbing-week and region. On univariable and multivariable analysis adjusted for underlying clinical risk factors, cases were no more or less likely than controls to be vaccinated with 2008-09 or 2007-08 season TIV. Adjusted vaccine effectiveness for the former was -6% (-43% to 22%). Vaccine effectiveness did not differ significantly by age-group or hospitalisation status. There was no evidence prior vaccination with TIV significantly altered subsequent risk of pandemic influenza H1N1 2009 infection. SN - 1873-2518 UR - https://www.unboundmedicine.com/medline/citation/21292008/No_effect_of_2008/09_seasonal_influenza_vaccination_on_the_risk_of_pandemic_H1N1_2009_influenza_infection_in_England_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(11)00085-5 DB - PRIME DP - Unbound Medicine ER -