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Outcomes of intrathecal baclofen (ITB) therapy in spacticity.
Turk Neurosurg. 2011 Jan; 21(1):59-65.TN

Abstract

AIM

Spasticity is associated with various neurological conditions. Intrathecal baclofen (ITB) is one of the popular treatments for severe spasticity. In this paper we present our experience in treating 30 patients with both spinal and supraspinal spasticity with chronic infusion of Baclofen to evaluate the long term efficacy of this treatment on spasticity, disability and pain, and to evaluate the side effects of intrathecal Baclofen.

MATERIAL AND METHODS

The medical records of 30 patients who underwent baclofen pump placement from 2000 to 2010 under Department of Neurosurgery at the University of Akdeniz at Antalya/Turkey, were reviewed. All study subjects had diffuse chronic, severe, and generalized spasticity (Ashworth score ≥ 3), and had shown inadequate response to various oral antispastic drugs including baclofen. All patients were evaluated by means of the Ashworth score, spasm frequency, Barthel index, Rankin scales and VAS.

RESULTS

Spasticity and spasm frequency and pain scores were clinically and statistically decreased in all patients.

CONCLUSION

ITB therapy increases the quality of lifestyle and functional independence by reducing not only cerebral but also spinal related spasticity in appropriately selected cases.

Authors+Show Affiliations

Akdeniz University, Faculty of Medicine, Department of Neurosurgery, Antalya, Turkey. tucar@akdeniz.edu.trNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21294093

Citation

Ucar, Tanju, et al. "Outcomes of Intrathecal Baclofen (ITB) Therapy in Spacticity." Turkish Neurosurgery, vol. 21, no. 1, 2011, pp. 59-65.
Ucar T, Kazan S, Turgut U, et al. Outcomes of intrathecal baclofen (ITB) therapy in spacticity. Turk Neurosurg. 2011;21(1):59-65.
Ucar, T., Kazan, S., Turgut, U., & Samanci, N. K. (2011). Outcomes of intrathecal baclofen (ITB) therapy in spacticity. Turkish Neurosurgery, 21(1), 59-65.
Ucar T, et al. Outcomes of Intrathecal Baclofen (ITB) Therapy in Spacticity. Turk Neurosurg. 2011;21(1):59-65. PubMed PMID: 21294093.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcomes of intrathecal baclofen (ITB) therapy in spacticity. AU - Ucar,Tanju, AU - Kazan,Saim, AU - Turgut,Umut, AU - Samanci,Nehir Karaman, PY - 2011/2/5/entrez PY - 2011/2/5/pubmed PY - 2011/4/5/medline SP - 59 EP - 65 JF - Turkish neurosurgery JO - Turk Neurosurg VL - 21 IS - 1 N2 - AIM: Spasticity is associated with various neurological conditions. Intrathecal baclofen (ITB) is one of the popular treatments for severe spasticity. In this paper we present our experience in treating 30 patients with both spinal and supraspinal spasticity with chronic infusion of Baclofen to evaluate the long term efficacy of this treatment on spasticity, disability and pain, and to evaluate the side effects of intrathecal Baclofen. MATERIAL AND METHODS: The medical records of 30 patients who underwent baclofen pump placement from 2000 to 2010 under Department of Neurosurgery at the University of Akdeniz at Antalya/Turkey, were reviewed. All study subjects had diffuse chronic, severe, and generalized spasticity (Ashworth score ≥ 3), and had shown inadequate response to various oral antispastic drugs including baclofen. All patients were evaluated by means of the Ashworth score, spasm frequency, Barthel index, Rankin scales and VAS. RESULTS: Spasticity and spasm frequency and pain scores were clinically and statistically decreased in all patients. CONCLUSION: ITB therapy increases the quality of lifestyle and functional independence by reducing not only cerebral but also spinal related spasticity in appropriately selected cases. SN - 1019-5149 UR - https://www.unboundmedicine.com/medline/citation/21294093/Outcomes_of_intrathecal_baclofen__ITB__therapy_in_spacticity_ L2 - http://www.turkishneurosurgery.org.tr/pubmed.php3?year=2011&volume=21&issue=1&page=59 DB - PRIME DP - Unbound Medicine ER -