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Second trimester uterine artery Doppler screening in prediction of adverse pregnancy outcome in high risk women.
J Med Assoc Thai 2010; 93 Suppl 7:S127-30JM

Abstract

OBJECTIVE

To assess the value of uterine artery colour Doppler waveform analysis in the prediction of adverse pregnancy outcome such as preeclampsia, fetal growth restriction in high risk pregnancy women.

MATERIAL AND METHOD

Uterine artery Doppler screening was performed as part of mid trimester screening between 20 and 24 weeks gestation in high risk pregnancy women at Matermal Fetal Medicine unit, Thammasat University Hospital between June 1, 2008 and May 31, 2009. A pulsatility index (PI) was calculated from each uterine artery and the presence or absence of a notch was determined. A PI of > 1.58 or the presence of any diastolic notch were defined as abnormal. The main outcome measures were pre-eclampsia and small for gestational aged baby (birth weight < 10th centile).

RESULTS

Doppler examination of the uterine arteries were performed in 330 singleton pregnancies. Twenty-seven (8.18%) women developed pre-eclampsia, 16 (4.84%) women had SGA babies. The sensitivity ofPI > 1.58 and diastolic notch for preeclampsia, SGA were 59.25% and 56.25%, respectively.The specificity of PI >1.58 and diastolic notch for these outcomes were 66.67% and 65.60% respectively.

CONCLUSION

In high-risk women, mid trimester uterine artery Doppler waveform analysis can not use as screening method in women at higher risk for the development of severe adverse outcome such as pre-eclampsia and SGA babies. However women with normal uterine artery Doppler results are unlikely to develop pre-eclampsia, fetal growth restriction (FGR) and therefore do not necessarily need repeated Doppler ultrasound follow-up.

Authors+Show Affiliations

Maternal Fetal Medicine Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand. pongrojpaw@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21294407

Citation

Pongrojpaw, Densak, et al. "Second Trimester Uterine Artery Doppler Screening in Prediction of Adverse Pregnancy Outcome in High Risk Women." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 93 Suppl 7, 2010, pp. S127-30.
Pongrojpaw D, Chanthasenanont A, Nanthakomon T. Second trimester uterine artery Doppler screening in prediction of adverse pregnancy outcome in high risk women. J Med Assoc Thai. 2010;93 Suppl 7:S127-30.
Pongrojpaw, D., Chanthasenanont, A., & Nanthakomon, T. (2010). Second trimester uterine artery Doppler screening in prediction of adverse pregnancy outcome in high risk women. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 93 Suppl 7, pp. S127-30.
Pongrojpaw D, Chanthasenanont A, Nanthakomon T. Second Trimester Uterine Artery Doppler Screening in Prediction of Adverse Pregnancy Outcome in High Risk Women. J Med Assoc Thai. 2010;93 Suppl 7:S127-30. PubMed PMID: 21294407.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Second trimester uterine artery Doppler screening in prediction of adverse pregnancy outcome in high risk women. AU - Pongrojpaw,Densak, AU - Chanthasenanont,Athita, AU - Nanthakomon,Tongta, PY - 2011/2/8/entrez PY - 2011/2/8/pubmed PY - 2011/3/15/medline SP - S127 EP - 30 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 93 Suppl 7 N2 - OBJECTIVE: To assess the value of uterine artery colour Doppler waveform analysis in the prediction of adverse pregnancy outcome such as preeclampsia, fetal growth restriction in high risk pregnancy women. MATERIAL AND METHOD: Uterine artery Doppler screening was performed as part of mid trimester screening between 20 and 24 weeks gestation in high risk pregnancy women at Matermal Fetal Medicine unit, Thammasat University Hospital between June 1, 2008 and May 31, 2009. A pulsatility index (PI) was calculated from each uterine artery and the presence or absence of a notch was determined. A PI of > 1.58 or the presence of any diastolic notch were defined as abnormal. The main outcome measures were pre-eclampsia and small for gestational aged baby (birth weight < 10th centile). RESULTS: Doppler examination of the uterine arteries were performed in 330 singleton pregnancies. Twenty-seven (8.18%) women developed pre-eclampsia, 16 (4.84%) women had SGA babies. The sensitivity ofPI > 1.58 and diastolic notch for preeclampsia, SGA were 59.25% and 56.25%, respectively.The specificity of PI >1.58 and diastolic notch for these outcomes were 66.67% and 65.60% respectively. CONCLUSION: In high-risk women, mid trimester uterine artery Doppler waveform analysis can not use as screening method in women at higher risk for the development of severe adverse outcome such as pre-eclampsia and SGA babies. However women with normal uterine artery Doppler results are unlikely to develop pre-eclampsia, fetal growth restriction (FGR) and therefore do not necessarily need repeated Doppler ultrasound follow-up. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/21294407/Second_trimester_uterine_artery_Doppler_screening_in_prediction_of_adverse_pregnancy_outcome_in_high_risk_women_ L2 - http://www.diseaseinfosearch.org/result/5922 DB - PRIME DP - Unbound Medicine ER -