Tags

Type your tag names separated by a space and hit enter

Aripiprazole for the treatment of irritability associated with autism.
Expert Opin Pharmacother. 2011 Mar; 12(4):635-40.EO

Abstract

INTRODUCTION

Irritability (including tantrums, aggression and moodiness) is often associated with autistic disorder. Children with autism are frequently prescribed atypical antipsychotic medications for these behaviors. Although multiple agents have been found to be effective, the safety and tolerability of each antipsychotic may be the determining factor in its selection.

AREAS COVERED

The pharmacokinetics, pharmacodynamics, safety and efficacy data on aripiprazole for the treatment of irritability associated with autism are discussed. Knowledge of the mechanism of action, advantages and disadvantages relative to other atypical antipsychotics, and an appreciation of the efficacy of aripiprazole when used to treat irritability in autism is also explored in this paper.

EXPERT OPINION

Aripiprazole may have a more favorable side-effect profile than another commonly prescribed medication, risperidone, because of its unique mechanism of action. It seems to be effective in treating irritability associated with autism, but more research is needed.

Authors+Show Affiliations

The Ohio State University, Nisonger Center, 1581 Dodd Drive, Columbus, OH 43210, USA. farmer.107@osu.eduNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Review

Language

eng

PubMed ID

21294670

Citation

Farmer, Cristan Ann, and Michael G. Aman. "Aripiprazole for the Treatment of Irritability Associated With Autism." Expert Opinion On Pharmacotherapy, vol. 12, no. 4, 2011, pp. 635-40.
Farmer CA, Aman MG. Aripiprazole for the treatment of irritability associated with autism. Expert Opin Pharmacother. 2011;12(4):635-40.
Farmer, C. A., & Aman, M. G. (2011). Aripiprazole for the treatment of irritability associated with autism. Expert Opinion On Pharmacotherapy, 12(4), 635-40. https://doi.org/10.1517/14656566.2011.557661
Farmer CA, Aman MG. Aripiprazole for the Treatment of Irritability Associated With Autism. Expert Opin Pharmacother. 2011;12(4):635-40. PubMed PMID: 21294670.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Aripiprazole for the treatment of irritability associated with autism. AU - Farmer,Cristan Ann, AU - Aman,Michael G, Y1 - 2011/02/06/ PY - 2011/2/8/entrez PY - 2011/2/8/pubmed PY - 2011/6/8/medline SP - 635 EP - 40 JF - Expert opinion on pharmacotherapy JO - Expert Opin Pharmacother VL - 12 IS - 4 N2 - INTRODUCTION: Irritability (including tantrums, aggression and moodiness) is often associated with autistic disorder. Children with autism are frequently prescribed atypical antipsychotic medications for these behaviors. Although multiple agents have been found to be effective, the safety and tolerability of each antipsychotic may be the determining factor in its selection. AREAS COVERED: The pharmacokinetics, pharmacodynamics, safety and efficacy data on aripiprazole for the treatment of irritability associated with autism are discussed. Knowledge of the mechanism of action, advantages and disadvantages relative to other atypical antipsychotics, and an appreciation of the efficacy of aripiprazole when used to treat irritability in autism is also explored in this paper. EXPERT OPINION: Aripiprazole may have a more favorable side-effect profile than another commonly prescribed medication, risperidone, because of its unique mechanism of action. It seems to be effective in treating irritability associated with autism, but more research is needed. SN - 1744-7666 UR - https://www.unboundmedicine.com/medline/citation/21294670/Aripiprazole_for_the_treatment_of_irritability_associated_with_autism_ L2 - http://www.tandfonline.com/doi/full/10.1517/14656566.2011.557661 DB - PRIME DP - Unbound Medicine ER -