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Rheumatic-musculoskeletal manifestations in type 2 diabetes mellitus patients in south India.
Int J Rheum Dis. 2011 Feb; 14(1):55-60.IJ

Abstract

AIM

To determine the prevalence of rheumatic musculoskeletal disorders (RMSD) in type 2 diabetes mellitus (T2DM) and study their risk factors.

METHODS

Diagnosed patients of T2DM attending the diabetic clinic in a premier teaching institution in south India were interviewed and requested to mark their RMS pain sites on a mannequin and intensity of pain on a visual analogue scale (VAS). A complete RMS examination was done and diagnoses were noted. These RMSDs were compared with those in age- and sex-matched, non-diabetic individuals from the general population. Association of RMSD with variables was determined using Chi-square test and multiple logistic regression models for risk factors were created using SPSS 17.0 software.

RESULTS

Prevalence of RMSD in 310 cases and controls was 42.58%; 95% CI: 37.08-48.08 and 31.61%; 95% CI: 26.43-36.79, respectively. RMS pain was marked by 194 individuals. Knee was the most common site of pain (33.4%). Prevalence of common RMSD was osteoarthritis knee (20.64%; 95% CI 16.14-25.16), frozen shoulder (16.45%; 95% CI: 12.32-20.58), diffuse idiopathic skeletal hyperostosis (14.52%; 95% CI: 10.6-18.44) and limited joint mobility (8.06%; 95% CI: 5.03-11.09). Age (P = 0.046), duration of T2DM (P < 0.001) and glycosylated hemoglobin (P < 0.001) were found to have significant associations with RMSD. In logistic regression analysis, duration (OR: 1.467; 95% CI: 1.210-1.779) and severity (OR: 1.354; 95% CI: 1.169-1.569) of T2DM were identified as the risk factors.

CONCLUSION

Thorough RMS examination should be included as an integral part of care in T2DM patients.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Mathew AJ
Department of Internal Medicine, Medical College Hospital, Trivandrum, Kerala, India. mathewaj@live.com
Nair JB
No affiliation info available
Pillai SS
No affiliation info available

MeSH

AdultAgedAged, 80 and overComorbidityDiabetes Mellitus, Type 2Diabetic NeuropathiesFemaleHumansIndiaJointsMaleMiddle AgedMusculoskeletal DiseasesPainPain MeasurementRange of Motion, Articular

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21303482

Citation

Mathew, Ashish J., et al. "Rheumatic-musculoskeletal Manifestations in Type 2 Diabetes Mellitus Patients in South India." International Journal of Rheumatic Diseases, vol. 14, no. 1, 2011, pp. 55-60.
Mathew AJ, Nair JB, Pillai SS. Rheumatic-musculoskeletal manifestations in type 2 diabetes mellitus patients in south India. Int J Rheum Dis. 2011;14(1):55-60.
Mathew, A. J., Nair, J. B., & Pillai, S. S. (2011). Rheumatic-musculoskeletal manifestations in type 2 diabetes mellitus patients in south India. International Journal of Rheumatic Diseases, 14(1), 55-60. https://doi.org/10.1111/j.1756-185X.2010.01587.x
Mathew AJ, Nair JB, Pillai SS. Rheumatic-musculoskeletal Manifestations in Type 2 Diabetes Mellitus Patients in South India. Int J Rheum Dis. 2011;14(1):55-60. PubMed PMID: 21303482.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rheumatic-musculoskeletal manifestations in type 2 diabetes mellitus patients in south India. AU - Mathew,Ashish J, AU - Nair,Jayakumar B, AU - Pillai,Saran S, Y1 - 2011/01/24/ PY - 2011/2/10/entrez PY - 2011/2/10/pubmed PY - 2011/6/1/medline SP - 55 EP - 60 JF - International journal of rheumatic diseases JO - Int J Rheum Dis VL - 14 IS - 1 N2 - AIM: To determine the prevalence of rheumatic musculoskeletal disorders (RMSD) in type 2 diabetes mellitus (T2DM) and study their risk factors. METHODS: Diagnosed patients of T2DM attending the diabetic clinic in a premier teaching institution in south India were interviewed and requested to mark their RMS pain sites on a mannequin and intensity of pain on a visual analogue scale (VAS). A complete RMS examination was done and diagnoses were noted. These RMSDs were compared with those in age- and sex-matched, non-diabetic individuals from the general population. Association of RMSD with variables was determined using Chi-square test and multiple logistic regression models for risk factors were created using SPSS 17.0 software. RESULTS: Prevalence of RMSD in 310 cases and controls was 42.58%; 95% CI: 37.08-48.08 and 31.61%; 95% CI: 26.43-36.79, respectively. RMS pain was marked by 194 individuals. Knee was the most common site of pain (33.4%). Prevalence of common RMSD was osteoarthritis knee (20.64%; 95% CI 16.14-25.16), frozen shoulder (16.45%; 95% CI: 12.32-20.58), diffuse idiopathic skeletal hyperostosis (14.52%; 95% CI: 10.6-18.44) and limited joint mobility (8.06%; 95% CI: 5.03-11.09). Age (P = 0.046), duration of T2DM (P < 0.001) and glycosylated hemoglobin (P < 0.001) were found to have significant associations with RMSD. In logistic regression analysis, duration (OR: 1.467; 95% CI: 1.210-1.779) and severity (OR: 1.354; 95% CI: 1.169-1.569) of T2DM were identified as the risk factors. CONCLUSION: Thorough RMS examination should be included as an integral part of care in T2DM patients. SN - 1756-185X UR - https://www.unboundmedicine.com/medline/citation/21303482/Rheumatic_musculoskeletal_manifestations_in_type_2_diabetes_mellitus_patients_in_south_India_ DB - PRIME DP - Unbound Medicine ER -