Tags

Type your tag names separated by a space and hit enter

Separation anxiety disorder in OCD.
Depress Anxiety. 2011 Mar; 28(3):256-62.DA

Abstract

BACKGROUND

A history of separation anxiety disorder (SAD) is frequently reported by patients with obsessive-compulsive disorder (OCD). The purpose of this study was to determine if there are clinical differences between OCD-affected individuals with, versus without, a history of SAD.

METHODS

Using data collected during the OCD Collaborative Genetic Study, we studied 470 adult OCD participants; 80 had a history of SAD, whereas 390 did not. These two groups were compared as to onset and severity of OCD, lifetime prevalence of Axis I disorders, and number of personality disorder traits.

RESULTS

OCD participants with a history of SAD were significantly younger than the non-SAD group (mean, 34.2 versus 42.2 years; P<.001). They had an earlier age of onset of OCD symptoms (mean, 8.0 versus 10.5 years; P<.003) and more severe OCD, as measured by the Yale-Brown Obsessive Compulsive Scale (mean, 27.5 versus 25.0; P<.005). In addition, those with a history of SAD had a significantly greater lifetime prevalence of agoraphobia (odds ratio (OR) = 2.52, 95% confidence interval (CI) = 1.4-4.6, P<.003), panic disorder (OR = 1.84, CI = 1.03-3.3 P<.04), social phobia (OR = 1.69, CI 1.01-2.8, P<.048), after adjusting for age at interview, age at onset of OCD, and OCD severity in logistic regression models. There was a strong relationship between the number of dependent personality disorder traits and SAD (adjusted OR = 1.42, CI = 1.2-1.6, P<.001).

CONCLUSIONS

A history of SAD is associated with anxiety disorders and dependent personality disorder traits in individuals with OCD.

Authors+Show Affiliations

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 1629 Thames Street, Baltimore, MD 21287, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21308883

Citation

Mroczkowski, Megan M., et al. "Separation Anxiety Disorder in OCD." Depression and Anxiety, vol. 28, no. 3, 2011, pp. 256-62.
Mroczkowski MM, Goes FS, Riddle MA, et al. Separation anxiety disorder in OCD. Depress Anxiety. 2011;28(3):256-62.
Mroczkowski, M. M., Goes, F. S., Riddle, M. A., Grados, M. A., Bienvenu, O. J., Greenberg, B. D., Fyer, A. J., McCracken, J. T., Rauch, S. L., Murphy, D. L., Knowles, J. A., Piacentini, J., Cullen, B., Rasmussen, S. A., Geller, D. A., Pauls, D. L., Liang, K. Y., Nestadt, G., & Samuels, J. F. (2011). Separation anxiety disorder in OCD. Depression and Anxiety, 28(3), 256-62. https://doi.org/10.1002/da.20773
Mroczkowski MM, et al. Separation Anxiety Disorder in OCD. Depress Anxiety. 2011;28(3):256-62. PubMed PMID: 21308883.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Separation anxiety disorder in OCD. AU - Mroczkowski,Megan M, AU - Goes,Fernando S, AU - Riddle,Mark A, AU - Grados,Marco A, AU - Bienvenu,O Joseph,3rd AU - Greenberg,Benjamin D, AU - Fyer,Abby J, AU - McCracken,James T, AU - Rauch,Scott L, AU - Murphy,Dennis L, AU - Knowles,James A, AU - Piacentini,John, AU - Cullen,Bernadette, AU - Rasmussen,Steven A, AU - Geller,Daniel A, AU - Pauls,David L, AU - Liang,Kung-Yee, AU - Nestadt,Gerald, AU - Samuels,Jack F, Y1 - 2011/02/09/ PY - 2010/08/11/received PY - 2010/10/26/revised PY - 2010/10/30/accepted PY - 2011/2/11/entrez PY - 2011/2/11/pubmed PY - 2011/7/28/medline SP - 256 EP - 62 JF - Depression and anxiety JO - Depress Anxiety VL - 28 IS - 3 N2 - BACKGROUND: A history of separation anxiety disorder (SAD) is frequently reported by patients with obsessive-compulsive disorder (OCD). The purpose of this study was to determine if there are clinical differences between OCD-affected individuals with, versus without, a history of SAD. METHODS: Using data collected during the OCD Collaborative Genetic Study, we studied 470 adult OCD participants; 80 had a history of SAD, whereas 390 did not. These two groups were compared as to onset and severity of OCD, lifetime prevalence of Axis I disorders, and number of personality disorder traits. RESULTS: OCD participants with a history of SAD were significantly younger than the non-SAD group (mean, 34.2 versus 42.2 years; P<.001). They had an earlier age of onset of OCD symptoms (mean, 8.0 versus 10.5 years; P<.003) and more severe OCD, as measured by the Yale-Brown Obsessive Compulsive Scale (mean, 27.5 versus 25.0; P<.005). In addition, those with a history of SAD had a significantly greater lifetime prevalence of agoraphobia (odds ratio (OR) = 2.52, 95% confidence interval (CI) = 1.4-4.6, P<.003), panic disorder (OR = 1.84, CI = 1.03-3.3 P<.04), social phobia (OR = 1.69, CI 1.01-2.8, P<.048), after adjusting for age at interview, age at onset of OCD, and OCD severity in logistic regression models. There was a strong relationship between the number of dependent personality disorder traits and SAD (adjusted OR = 1.42, CI = 1.2-1.6, P<.001). CONCLUSIONS: A history of SAD is associated with anxiety disorders and dependent personality disorder traits in individuals with OCD. SN - 1520-6394 UR - https://www.unboundmedicine.com/medline/citation/21308883/Separation_anxiety_disorder_in_OCD_ L2 - https://doi.org/10.1002/da.20773 DB - PRIME DP - Unbound Medicine ER -