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Management of hepatitis C virus genotype 4: recommendations of an international expert panel.
J Hepatol. 2011 Jun; 54(6):1250-62.JH

Abstract

HCV has been classified into no fewer than six major genotypes and a series of subtypes. Each HCV genotype is unique with respect to its nucleotide sequence, geographic distribution, and response to therapy. Genotypes 1, 2, and 3 are common throughout North America and Europe. HCV genotype 4 (HCV-4) is common in the Middle East and in Africa, where it is responsible for more than 80% of HCV infections. It has recently spread to several European countries. HCV-4 is considered a major cause of chronic hepatitis, cirrhosis, hepatocellular carcinoma, and liver transplantation in these regions. Although HCV-4 is the cause of approximately 20% of the 170 million cases of chronic hepatitis C in the world, it has not been the subject of widespread research. Therefore, this document, drafted by a panel of international experts, aimed to review current knowledge on the epidemiology, natural history, clinical, histological features, and treatment of HCV-4 infections.

Authors+Show Affiliations

Department of Internal Medicine, University of Minia, Egypt. mkhattabmed@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21316497

Citation

Khattab, Mahmoud A., et al. "Management of Hepatitis C Virus Genotype 4: Recommendations of an International Expert Panel." Journal of Hepatology, vol. 54, no. 6, 2011, pp. 1250-62.
Khattab MA, Ferenci P, Hadziyannis SJ, et al. Management of hepatitis C virus genotype 4: recommendations of an international expert panel. J Hepatol. 2011;54(6):1250-62.
Khattab, M. A., Ferenci, P., Hadziyannis, S. J., Colombo, M., Manns, M. P., Almasio, P. L., Esteban, R., Abdo, A. A., Harrison, S. A., Ibrahim, N., Cacoub, P., Eslam, M., & Lee, S. S. (2011). Management of hepatitis C virus genotype 4: recommendations of an international expert panel. Journal of Hepatology, 54(6), 1250-62. https://doi.org/10.1016/j.jhep.2010.11.016
Khattab MA, et al. Management of Hepatitis C Virus Genotype 4: Recommendations of an International Expert Panel. J Hepatol. 2011;54(6):1250-62. PubMed PMID: 21316497.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Management of hepatitis C virus genotype 4: recommendations of an international expert panel. AU - Khattab,Mahmoud A, AU - Ferenci,Peter, AU - Hadziyannis,Stephanos J, AU - Colombo,Massimo, AU - Manns,Michael P, AU - Almasio,Piero L, AU - Esteban,Rafael, AU - Abdo,Ayman A, AU - Harrison,Stephen A, AU - Ibrahim,Nazir, AU - Cacoub,Patrice, AU - Eslam,Mohammed, AU - Lee,Samuel S, Y1 - 2010/12/08/ PY - 2010/10/04/received PY - 2010/11/17/revised PY - 2010/11/23/accepted PY - 2011/2/15/entrez PY - 2011/2/15/pubmed PY - 2011/9/29/medline SP - 1250 EP - 62 JF - Journal of hepatology JO - J Hepatol VL - 54 IS - 6 N2 - HCV has been classified into no fewer than six major genotypes and a series of subtypes. Each HCV genotype is unique with respect to its nucleotide sequence, geographic distribution, and response to therapy. Genotypes 1, 2, and 3 are common throughout North America and Europe. HCV genotype 4 (HCV-4) is common in the Middle East and in Africa, where it is responsible for more than 80% of HCV infections. It has recently spread to several European countries. HCV-4 is considered a major cause of chronic hepatitis, cirrhosis, hepatocellular carcinoma, and liver transplantation in these regions. Although HCV-4 is the cause of approximately 20% of the 170 million cases of chronic hepatitis C in the world, it has not been the subject of widespread research. Therefore, this document, drafted by a panel of international experts, aimed to review current knowledge on the epidemiology, natural history, clinical, histological features, and treatment of HCV-4 infections. SN - 1600-0641 UR - https://www.unboundmedicine.com/medline/citation/21316497/Management_of_hepatitis_C_virus_genotype_4:_recommendations_of_an_international_expert_panel_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0168-8278(10)01107-4 DB - PRIME DP - Unbound Medicine ER -