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Diabetes risk score in the diagnostic categories of polycystic ovary syndrome.
Fertil Steril. 2011 Apr; 95(5):1742-8.FS

Abstract

OBJECTIVE

To assess the Finnish Diabetes Risk Score in polycystic ovary syndrome (PCOS) and in different phenotypes of PCOS and controls.

DESIGN

Cross-sectional study.

SETTING

General community.

PATIENT(S)

Overweight premenopausal women with National Institutes of Health (NIH) PCOS (n = 29), non-NIH PCOS (n = 25), or controls (n = 27).

INTERVENTION(S)

No intervention provided.

MAIN OUTCOME MEASURE(S)

Finnish Diabetes Risk Score, anthropometrics, oral glucose tolerance test (OGTT), glucose, insulin, and reproductive hormone levels.

RESULT(S)

The women with NIH PCOS had higher adiposity, abdominal adiposity and 120-minute OGTT glucose. The women with NIH and non-NIH PCOS had elevated 120-minute OGTT insulin compared with controls. The women with NIH (11.3 ± 0.7) and non-NIH PCOS (10.4 ± 0.7) had similar diabetes risk scores, but both had higher diabetes risk score compared with controls (7.6 ± 0.8) maintained on adjustment for age and body mass index (BMI). The women with NIH (4%) and non-NIH PCOS (12%) had a lower prevalence of low risk of diabetes scores compared with controls (50%).

CONCLUSION(S)

We report for the first time that women with NIH and non-NIH PCOS have similar Finnish Diabetes Risk Scores and elevated scores relative to controls independent of age and adiposity. Similar clinical screening and treatment practices for type 2 diabetes are warranted for both phenotypes of PCOS.

Authors+Show Affiliations

The Jean Hailes Clinical Research Unit, School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia. lisa.moran@med.monash.edu.auNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Validation Study

Language

eng

PubMed ID

21316662

Citation

Moran, Lisa J., et al. "Diabetes Risk Score in the Diagnostic Categories of Polycystic Ovary Syndrome." Fertility and Sterility, vol. 95, no. 5, 2011, pp. 1742-8.
Moran LJ, Strauss BJ, Teede HJ. Diabetes risk score in the diagnostic categories of polycystic ovary syndrome. Fertil Steril. 2011;95(5):1742-8.
Moran, L. J., Strauss, B. J., & Teede, H. J. (2011). Diabetes risk score in the diagnostic categories of polycystic ovary syndrome. Fertility and Sterility, 95(5), 1742-8. https://doi.org/10.1016/j.fertnstert.2011.01.133
Moran LJ, Strauss BJ, Teede HJ. Diabetes Risk Score in the Diagnostic Categories of Polycystic Ovary Syndrome. Fertil Steril. 2011;95(5):1742-8. PubMed PMID: 21316662.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diabetes risk score in the diagnostic categories of polycystic ovary syndrome. AU - Moran,Lisa J, AU - Strauss,Boyd J, AU - Teede,Helena J, Y1 - 2011/02/12/ PY - 2010/10/29/received PY - 2011/01/06/revised PY - 2011/01/10/accepted PY - 2011/2/15/entrez PY - 2011/2/15/pubmed PY - 2011/5/12/medline SP - 1742 EP - 8 JF - Fertility and sterility JO - Fertil. Steril. VL - 95 IS - 5 N2 - OBJECTIVE: To assess the Finnish Diabetes Risk Score in polycystic ovary syndrome (PCOS) and in different phenotypes of PCOS and controls. DESIGN: Cross-sectional study. SETTING: General community. PATIENT(S): Overweight premenopausal women with National Institutes of Health (NIH) PCOS (n = 29), non-NIH PCOS (n = 25), or controls (n = 27). INTERVENTION(S): No intervention provided. MAIN OUTCOME MEASURE(S): Finnish Diabetes Risk Score, anthropometrics, oral glucose tolerance test (OGTT), glucose, insulin, and reproductive hormone levels. RESULT(S): The women with NIH PCOS had higher adiposity, abdominal adiposity and 120-minute OGTT glucose. The women with NIH and non-NIH PCOS had elevated 120-minute OGTT insulin compared with controls. The women with NIH (11.3 ± 0.7) and non-NIH PCOS (10.4 ± 0.7) had similar diabetes risk scores, but both had higher diabetes risk score compared with controls (7.6 ± 0.8) maintained on adjustment for age and body mass index (BMI). The women with NIH (4%) and non-NIH PCOS (12%) had a lower prevalence of low risk of diabetes scores compared with controls (50%). CONCLUSION(S): We report for the first time that women with NIH and non-NIH PCOS have similar Finnish Diabetes Risk Scores and elevated scores relative to controls independent of age and adiposity. Similar clinical screening and treatment practices for type 2 diabetes are warranted for both phenotypes of PCOS. SN - 1556-5653 UR - https://www.unboundmedicine.com/medline/citation/21316662/Diabetes_risk_score_in_the_diagnostic_categories_of_polycystic_ovary_syndrome_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0015-0282(11)00167-1 DB - PRIME DP - Unbound Medicine ER -