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Quality of life measurement and its relationship to disease severity in children with atopic dermatitis in general practice.
Acta Derm Venereol. 2011 Mar; 91(2):147-51.AD

Abstract

Atopic dermatitis (AD) has a big impact on quality of life. The usefulness of health-related quality of life questionnaires for children with AD in general practice, and the relationship of quality of life to disease severity, as assessed by parents and by investigators, however, is not known. This study used the Infants' Dermatitis Quality of Life Index (IDQoL) to assess quality of life in children with AD selected from general practice. Severity of AD was determined by investigators and parents using the objective SCORAD (SCORing Atopic Dermatitis), the TIS (three-item severity scale), or by an additional question on the IDQoL. A total of 66 patients (41% boys, mean age 31 months) were included. Correlations between disease severity assessed by parents and by investigators were low (Rs 0.29-0.51). Correlations between IDQoL and severity assessed by investigators were also low (Rs 0.08-0.36). However, correlations between IDQoL and severity according to parents were high (Rs 0.67-0.73). In conclusion, disease severity and disease-related quality of life are different aspects of AD and must be taken into consideration when evaluating treatment or investigating new dermatological therapies in trials.

Authors+Show Affiliations

Department of General Practice, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21327320

Citation

van Valburg, Rosalinda W C., et al. "Quality of Life Measurement and Its Relationship to Disease Severity in Children With Atopic Dermatitis in General Practice." Acta Dermato-venereologica, vol. 91, no. 2, 2011, pp. 147-51.
van Valburg RW, Willemsen MG, Dirven-Meijer PC, et al. Quality of life measurement and its relationship to disease severity in children with atopic dermatitis in general practice. Acta Derm Venereol. 2011;91(2):147-51.
van Valburg, R. W., Willemsen, M. G., Dirven-Meijer, P. C., Oranje, A. P., van der Wouden, J. C., & Moed, H. (2011). Quality of life measurement and its relationship to disease severity in children with atopic dermatitis in general practice. Acta Dermato-venereologica, 91(2), 147-51. https://doi.org/10.2340/00015555-1026
van Valburg RW, et al. Quality of Life Measurement and Its Relationship to Disease Severity in Children With Atopic Dermatitis in General Practice. Acta Derm Venereol. 2011;91(2):147-51. PubMed PMID: 21327320.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Quality of life measurement and its relationship to disease severity in children with atopic dermatitis in general practice. AU - van Valburg,Rosalinda W C, AU - Willemsen,Marjolein G, AU - Dirven-Meijer,Pauline C, AU - Oranje,Arnold Pieter, AU - van der Wouden,Johannes C, AU - Moed,Heleen, PY - 2011/2/18/entrez PY - 2011/2/18/pubmed PY - 2011/7/26/medline SP - 147 EP - 51 JF - Acta dermato-venereologica JO - Acta Derm Venereol VL - 91 IS - 2 N2 - Atopic dermatitis (AD) has a big impact on quality of life. The usefulness of health-related quality of life questionnaires for children with AD in general practice, and the relationship of quality of life to disease severity, as assessed by parents and by investigators, however, is not known. This study used the Infants' Dermatitis Quality of Life Index (IDQoL) to assess quality of life in children with AD selected from general practice. Severity of AD was determined by investigators and parents using the objective SCORAD (SCORing Atopic Dermatitis), the TIS (three-item severity scale), or by an additional question on the IDQoL. A total of 66 patients (41% boys, mean age 31 months) were included. Correlations between disease severity assessed by parents and by investigators were low (Rs 0.29-0.51). Correlations between IDQoL and severity assessed by investigators were also low (Rs 0.08-0.36). However, correlations between IDQoL and severity according to parents were high (Rs 0.67-0.73). In conclusion, disease severity and disease-related quality of life are different aspects of AD and must be taken into consideration when evaluating treatment or investigating new dermatological therapies in trials. SN - 1651-2057 UR - https://www.unboundmedicine.com/medline/citation/21327320/Quality_of_life_measurement_and_its_relationship_to_disease_severity_in_children_with_atopic_dermatitis_in_general_practice_ L2 - https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-1026 DB - PRIME DP - Unbound Medicine ER -