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Tamsulosin versus transurethral resection of the prostate: effect on nocturia as a result of benign prostatic hyperplasia.
Int J Urol. 2011 Mar; 18(3):243-8.IJ

Abstract

Our objective was to compare the effect of tamsulosin versus transurethral resection of the prostate (TURP) for the management of nocturia in previously untreated men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and no other predisposing factors for nocturia. The study group included 66 patients (mean age 68.9 years, range 52-81) randomized to receive either tamsulosin 0.4 mg per os daily (n = 33) or TURP (n = 33). Nocturia was assessed at baseline, after 3 months and after 1 year, by the number of nocturnal awakenings and hours of undisturbed sleep (HUS) obtained from a 72-h Frequency Volume Chart (FVC). Furthermore, the International Prostate Symptom Score (IPSS), the International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) and the International Consultation on Incontinence Questionnaire Nocturia Quality of Life (ICIQ-NQoL) were recorded. At baseline, there were no statistically significant differences between the two groups. ICIQNQoL and ICIQ-N scores correlated with the number of awakenings and HUS, respectively. Both tamsulosin and TURP improved all examined parameters during the follow up. TURP was associated with a statistically significant improvement in the number of nocturnal awakenings and in the IPSS, ICIQ-N and ICIQ-NQol scores in comparison with tamsulosin. HUS increased in both groups, but without any statistically significant difference. In conclusion, TURP is superior in comparison with tamsulosin for the management of BPH-related nocturia.

Authors+Show Affiliations

Department of Urology, Nikaia General Hospital, Athens, Greece.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

21332817

Citation

Simaioforidis, Vasileios, et al. "Tamsulosin Versus Transurethral Resection of the Prostate: Effect On Nocturia as a Result of Benign Prostatic Hyperplasia." International Journal of Urology : Official Journal of the Japanese Urological Association, vol. 18, no. 3, 2011, pp. 243-8.
Simaioforidis V, Papatsoris AG, Chrisofos M, et al. Tamsulosin versus transurethral resection of the prostate: effect on nocturia as a result of benign prostatic hyperplasia. Int J Urol. 2011;18(3):243-8.
Simaioforidis, V., Papatsoris, A. G., Chrisofos, M., Chrisafis, M., Koritsiadis, S., & Deliveliotis, C. (2011). Tamsulosin versus transurethral resection of the prostate: effect on nocturia as a result of benign prostatic hyperplasia. International Journal of Urology : Official Journal of the Japanese Urological Association, 18(3), 243-8. https://doi.org/10.1111/j.1442-2042.2010.02704.x
Simaioforidis V, et al. Tamsulosin Versus Transurethral Resection of the Prostate: Effect On Nocturia as a Result of Benign Prostatic Hyperplasia. Int J Urol. 2011;18(3):243-8. PubMed PMID: 21332817.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tamsulosin versus transurethral resection of the prostate: effect on nocturia as a result of benign prostatic hyperplasia. AU - Simaioforidis,Vasileios, AU - Papatsoris,Athanasios G, AU - Chrisofos,Michael, AU - Chrisafis,Manolis, AU - Koritsiadis,Sotirios, AU - Deliveliotis,Charalambos, PY - 2011/2/22/entrez PY - 2011/2/22/pubmed PY - 2011/6/22/medline SP - 243 EP - 8 JF - International journal of urology : official journal of the Japanese Urological Association JO - Int J Urol VL - 18 IS - 3 N2 - Our objective was to compare the effect of tamsulosin versus transurethral resection of the prostate (TURP) for the management of nocturia in previously untreated men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and no other predisposing factors for nocturia. The study group included 66 patients (mean age 68.9 years, range 52-81) randomized to receive either tamsulosin 0.4 mg per os daily (n = 33) or TURP (n = 33). Nocturia was assessed at baseline, after 3 months and after 1 year, by the number of nocturnal awakenings and hours of undisturbed sleep (HUS) obtained from a 72-h Frequency Volume Chart (FVC). Furthermore, the International Prostate Symptom Score (IPSS), the International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) and the International Consultation on Incontinence Questionnaire Nocturia Quality of Life (ICIQ-NQoL) were recorded. At baseline, there were no statistically significant differences between the two groups. ICIQNQoL and ICIQ-N scores correlated with the number of awakenings and HUS, respectively. Both tamsulosin and TURP improved all examined parameters during the follow up. TURP was associated with a statistically significant improvement in the number of nocturnal awakenings and in the IPSS, ICIQ-N and ICIQ-NQol scores in comparison with tamsulosin. HUS increased in both groups, but without any statistically significant difference. In conclusion, TURP is superior in comparison with tamsulosin for the management of BPH-related nocturia. SN - 1442-2042 UR - https://www.unboundmedicine.com/medline/citation/21332817/Tamsulosin_versus_transurethral_resection_of_the_prostate:_effect_on_nocturia_as_a_result_of_benign_prostatic_hyperplasia_ DB - PRIME DP - Unbound Medicine ER -