Tags

Type your tag names separated by a space and hit enter

Posterior cranial fossa morphometry in symptomatic adult Chiari I malformation patients: comparative clinical and anatomical study.
Clin Neurol Neurosurg. 2011 Jun; 113(5):399-403.CN

Abstract

BACKGROUND AND OBJECTIVES

The cerebellar tonsillar herniation occurring in Chiari malformation Type I (CMI) mainly results from overcrowding of a normally developing hindbrain within a primary small posterior cranial fossa (PCF) due to an anomaly in the embryological development of the occipital bone. In the present study, the lengths of PCF parameters were studied in adult CMI patients.

PATIENTS AND METHODS

The authors retrospectively examined 15 adult patients with CMI. Multiple measurements were made on magnetic resonance images (MRIs). The results were compared with the findings in 25 controls and 30 dry skulls.

RESULTS

Length of the neural structures did not significantly differ between the CMI and the control groups. The average length of the basiocciput was significantly shorter in the CMI group as compared with the control group. The mean length of the supraocciput was significantly shorter and the average diameter of the foramen magnum was significantly longer in the CMI group when compared to the control group and dry skulls.

CONCLUSIONS

The morphometric data suggest that, in CMI, a hypoplastic occipital bone, possibly due to the paraxial mesodermal defect of the parachordal plate, causes overcrowding in PCF, which contains the normally developed neural structures.

Authors+Show Affiliations

Mersin University Medical Faculty, Department of Neurosurgery, Mersin, Turkey. dagtekin69@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

21333437

Citation

Dagtekin, Ahmet, et al. "Posterior Cranial Fossa Morphometry in Symptomatic Adult Chiari I Malformation Patients: Comparative Clinical and Anatomical Study." Clinical Neurology and Neurosurgery, vol. 113, no. 5, 2011, pp. 399-403.
Dagtekin A, Avci E, Kara E, et al. Posterior cranial fossa morphometry in symptomatic adult Chiari I malformation patients: comparative clinical and anatomical study. Clin Neurol Neurosurg. 2011;113(5):399-403.
Dagtekin, A., Avci, E., Kara, E., Uzmansel, D., Dagtekin, O., Koseoglu, A., Talas, D., & Bagdatoglu, C. (2011). Posterior cranial fossa morphometry in symptomatic adult Chiari I malformation patients: comparative clinical and anatomical study. Clinical Neurology and Neurosurgery, 113(5), 399-403. https://doi.org/10.1016/j.clineuro.2010.12.020
Dagtekin A, et al. Posterior Cranial Fossa Morphometry in Symptomatic Adult Chiari I Malformation Patients: Comparative Clinical and Anatomical Study. Clin Neurol Neurosurg. 2011;113(5):399-403. PubMed PMID: 21333437.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Posterior cranial fossa morphometry in symptomatic adult Chiari I malformation patients: comparative clinical and anatomical study. AU - Dagtekin,Ahmet, AU - Avci,Emel, AU - Kara,Engin, AU - Uzmansel,Deniz, AU - Dagtekin,Oykut, AU - Koseoglu,Aslihan, AU - Talas,Derya, AU - Bagdatoglu,Celal, Y1 - 2011/02/18/ PY - 2010/05/26/received PY - 2010/11/01/revised PY - 2010/12/26/accepted PY - 2011/2/22/entrez PY - 2011/2/22/pubmed PY - 2011/9/7/medline SP - 399 EP - 403 JF - Clinical neurology and neurosurgery JO - Clin Neurol Neurosurg VL - 113 IS - 5 N2 - BACKGROUND AND OBJECTIVES: The cerebellar tonsillar herniation occurring in Chiari malformation Type I (CMI) mainly results from overcrowding of a normally developing hindbrain within a primary small posterior cranial fossa (PCF) due to an anomaly in the embryological development of the occipital bone. In the present study, the lengths of PCF parameters were studied in adult CMI patients. PATIENTS AND METHODS: The authors retrospectively examined 15 adult patients with CMI. Multiple measurements were made on magnetic resonance images (MRIs). The results were compared with the findings in 25 controls and 30 dry skulls. RESULTS: Length of the neural structures did not significantly differ between the CMI and the control groups. The average length of the basiocciput was significantly shorter in the CMI group as compared with the control group. The mean length of the supraocciput was significantly shorter and the average diameter of the foramen magnum was significantly longer in the CMI group when compared to the control group and dry skulls. CONCLUSIONS: The morphometric data suggest that, in CMI, a hypoplastic occipital bone, possibly due to the paraxial mesodermal defect of the parachordal plate, causes overcrowding in PCF, which contains the normally developed neural structures. SN - 1872-6968 UR - https://www.unboundmedicine.com/medline/citation/21333437/Posterior_cranial_fossa_morphometry_in_symptomatic_adult_Chiari_I_malformation_patients:_comparative_clinical_and_anatomical_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0303-8467(11)00008-4 DB - PRIME DP - Unbound Medicine ER -