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Bilateral subthalamic deep brain stimulation after bilateral pallidal deep brain stimulation for Parkinson's disease.
Stereotact Funct Neurosurg. 2011; 89(2):123-7.SF

Abstract

BACKGROUND/OBJECTIVE

Globus pallidus internus (GPi) and subthalamic nucleus (STN) have successfully been targeted independently for deep brain stimulator (DBS) placement in medically intractable Parkinson's disease (PD). Bilateral implantation of STN DBS in a patient with preexisting, functioning GPi DBS to specifically treat motor fluctuations is, to our knowledge, yet unreported.

CLINICAL PRESENTATION

We present a case of PD who had well-placed bilateral GPi DBS that controlled dyskinesia effectively and improved the motor symptoms like rigidity and akinesia. It did not improve her motor fluctuations and failed to reduce her medications.

METHODS

We implanted bilateral STN DBS, which improved her 'on' time, reduced her medications and improved her motor scores.

RESULTS/CONCLUSION

In this report we discuss the rationale, technical issues, programming nuances and outcome in a patient with preexisting bilateral GPi DBS who was implanted with bilateral STN DBS.

Authors+Show Affiliations

Center for Neurological Restoration, Neurological Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA. deoganm@ccf.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21336008

Citation

Deogaonkar, Milind, et al. "Bilateral Subthalamic Deep Brain Stimulation After Bilateral Pallidal Deep Brain Stimulation for Parkinson's Disease." Stereotactic and Functional Neurosurgery, vol. 89, no. 2, 2011, pp. 123-7.
Deogaonkar M, Monsalve GA, Scott J, et al. Bilateral subthalamic deep brain stimulation after bilateral pallidal deep brain stimulation for Parkinson's disease. Stereotact Funct Neurosurg. 2011;89(2):123-7.
Deogaonkar, M., Monsalve, G. A., Scott, J., Ahmed, A., & Rezai, A. (2011). Bilateral subthalamic deep brain stimulation after bilateral pallidal deep brain stimulation for Parkinson's disease. Stereotactic and Functional Neurosurgery, 89(2), 123-7. https://doi.org/10.1159/000323375
Deogaonkar M, et al. Bilateral Subthalamic Deep Brain Stimulation After Bilateral Pallidal Deep Brain Stimulation for Parkinson's Disease. Stereotact Funct Neurosurg. 2011;89(2):123-7. PubMed PMID: 21336008.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bilateral subthalamic deep brain stimulation after bilateral pallidal deep brain stimulation for Parkinson's disease. AU - Deogaonkar,Milind, AU - Monsalve,Guillermo A, AU - Scott,Jenera, AU - Ahmed,Anwar, AU - Rezai,Ali, Y1 - 2011/02/17/ PY - 2010/06/04/received PY - 2010/12/03/accepted PY - 2011/2/22/entrez PY - 2011/2/22/pubmed PY - 2011/8/24/medline SP - 123 EP - 7 JF - Stereotactic and functional neurosurgery JO - Stereotact Funct Neurosurg VL - 89 IS - 2 N2 - BACKGROUND/OBJECTIVE: Globus pallidus internus (GPi) and subthalamic nucleus (STN) have successfully been targeted independently for deep brain stimulator (DBS) placement in medically intractable Parkinson's disease (PD). Bilateral implantation of STN DBS in a patient with preexisting, functioning GPi DBS to specifically treat motor fluctuations is, to our knowledge, yet unreported. CLINICAL PRESENTATION: We present a case of PD who had well-placed bilateral GPi DBS that controlled dyskinesia effectively and improved the motor symptoms like rigidity and akinesia. It did not improve her motor fluctuations and failed to reduce her medications. METHODS: We implanted bilateral STN DBS, which improved her 'on' time, reduced her medications and improved her motor scores. RESULTS/CONCLUSION: In this report we discuss the rationale, technical issues, programming nuances and outcome in a patient with preexisting bilateral GPi DBS who was implanted with bilateral STN DBS. SN - 1423-0372 UR - https://www.unboundmedicine.com/medline/citation/21336008/Bilateral_subthalamic_deep_brain_stimulation_after_bilateral_pallidal_deep_brain_stimulation_for_Parkinson's_disease_ L2 - https://www.karger.com?DOI=10.1159/000323375 DB - PRIME DP - Unbound Medicine ER -