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Investigation of pulmonary infection pathogens in neurological intensive care unit.
Ther Clin Risk Manag 2011; 7:21-5TC

Abstract

PURPOSE

The purpose of this study is to investigate the distribution and antimicrobial susceptibility of pathogenic bacteria in inpatients with pulmonary infection in the neurological intensive care unit (NICU).

METHODS

A total of 947 sputum specimens of 428 inpatients from May 2007 to May 2008 in the NICU were enrolled in the study, and bacterial identification and antibiotic susceptibility tests were analyzed using a VITEK 2 system.

RESULTS

A total of 400 positive bacterial strains were separated from 947 sputum specimens, with Gram-negative bacteria accounting for 69.0% of the total strains collected. The most common strain of Gram-negative bacteria was Klebsiella pneumoniae (20.5%). Gram-positive bacteria accounted for 10.0% of the total strains, with the most common strain being Staphylococcus aureus (2.5%). Fungal species accounted for 21.0% of the total strains, and the most common strain collected was Candida albicans (12.25%). Imipenem was the most effective antibiotic against Gram-positive and Gram-negative bacteria. The drug resistance rate of Gram-positive bacteria to penicillin G was 100%, and the Gram-positive bacteria were 100% sensitive to teicoplanin, vancomycin, and linezolid.

CONCLUSIONS

Gram-negative bacterial infections account for the majority of pulmonary infections in the NICU, with fungal infections being the second most common infection type observed. In addition, fungal infections seem to be related to mortality in the NICU.

Authors+Show Affiliations

Department of Neurology, The First Affiliated Hospital of Chongqing, Medical University, Chongqing, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21339939

Citation

Quan, Fengying, et al. "Investigation of Pulmonary Infection Pathogens in Neurological Intensive Care Unit." Therapeutics and Clinical Risk Management, vol. 7, 2011, pp. 21-5.
Quan F, Liu G, Wang L, et al. Investigation of pulmonary infection pathogens in neurological intensive care unit. Ther Clin Risk Manag. 2011;7:21-5.
Quan, F., Liu, G., Wang, L., & Wang, X. (2011). Investigation of pulmonary infection pathogens in neurological intensive care unit. Therapeutics and Clinical Risk Management, 7, pp. 21-5. doi:10.2147/TCRM.S15730.
Quan F, et al. Investigation of Pulmonary Infection Pathogens in Neurological Intensive Care Unit. Ther Clin Risk Manag. 2011 Jan 21;7:21-5. PubMed PMID: 21339939.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Investigation of pulmonary infection pathogens in neurological intensive care unit. AU - Quan,Fengying, AU - Liu,Guangwei, AU - Wang,Liang, AU - Wang,Xuefeng, Y1 - 2011/01/21/ PY - 2011/01/20/received PY - 2011/2/23/entrez PY - 2011/2/23/pubmed PY - 2011/2/23/medline KW - drug resistance KW - neurological intensive care unit KW - nosocomial infection KW - pulmonary infection SP - 21 EP - 5 JF - Therapeutics and clinical risk management JO - Ther Clin Risk Manag VL - 7 N2 - PURPOSE: The purpose of this study is to investigate the distribution and antimicrobial susceptibility of pathogenic bacteria in inpatients with pulmonary infection in the neurological intensive care unit (NICU). METHODS: A total of 947 sputum specimens of 428 inpatients from May 2007 to May 2008 in the NICU were enrolled in the study, and bacterial identification and antibiotic susceptibility tests were analyzed using a VITEK 2 system. RESULTS: A total of 400 positive bacterial strains were separated from 947 sputum specimens, with Gram-negative bacteria accounting for 69.0% of the total strains collected. The most common strain of Gram-negative bacteria was Klebsiella pneumoniae (20.5%). Gram-positive bacteria accounted for 10.0% of the total strains, with the most common strain being Staphylococcus aureus (2.5%). Fungal species accounted for 21.0% of the total strains, and the most common strain collected was Candida albicans (12.25%). Imipenem was the most effective antibiotic against Gram-positive and Gram-negative bacteria. The drug resistance rate of Gram-positive bacteria to penicillin G was 100%, and the Gram-positive bacteria were 100% sensitive to teicoplanin, vancomycin, and linezolid. CONCLUSIONS: Gram-negative bacterial infections account for the majority of pulmonary infections in the NICU, with fungal infections being the second most common infection type observed. In addition, fungal infections seem to be related to mortality in the NICU. SN - 1178-203X UR - https://www.unboundmedicine.com/medline/citation/21339939/Investigation_of_pulmonary_infection_pathogens_in_neurological_intensive_care_unit_ L2 - https://dx.doi.org/10.2147/TCRM.S15730 DB - PRIME DP - Unbound Medicine ER -