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Serological response to trivalent inactive influenza vaccine in HIV-infected children with different immunologic status.
Vaccine. 2011 Apr 05; 29(16):3055-60.V

Abstract

Influenza vaccination is usually recommended for HIV-infected children. One hundred and twenty seven HIV-infected and twenty-one HIV-uninfected children aged ≥6 months to <18 years, all of whom were naïve to influenza vaccine, were enrolled to receive an influenza Trivalent Inactivated Vaccine (TIV). In the HIV group, the post-vaccination immune response (geometric mean titer, seroconversion and seroprotection rates) correlated with their immunological status before vaccination. The HIV-infected children with no immunosuppression had comparable serological response to HIV-uninfected children. For moderately and severely immunosuppressed HIV groups, two doses of TIV resulted in greater serological responses and should be recommended in these groups.

Authors+Show Affiliations

Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Thailand. pkosalaraksa@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

21349365

Citation

Kosalaraksa, Pope, et al. "Serological Response to Trivalent Inactive Influenza Vaccine in HIV-infected Children With Different Immunologic Status." Vaccine, vol. 29, no. 16, 2011, pp. 3055-60.
Kosalaraksa P, Srirompotong U, Newman RW, et al. Serological response to trivalent inactive influenza vaccine in HIV-infected children with different immunologic status. Vaccine. 2011;29(16):3055-60.
Kosalaraksa, P., Srirompotong, U., Newman, R. W., Lumbiganon, P., & Wood, J. M. (2011). Serological response to trivalent inactive influenza vaccine in HIV-infected children with different immunologic status. Vaccine, 29(16), 3055-60. https://doi.org/10.1016/j.vaccine.2011.01.091
Kosalaraksa P, et al. Serological Response to Trivalent Inactive Influenza Vaccine in HIV-infected Children With Different Immunologic Status. Vaccine. 2011 Apr 5;29(16):3055-60. PubMed PMID: 21349365.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serological response to trivalent inactive influenza vaccine in HIV-infected children with different immunologic status. AU - Kosalaraksa,Pope, AU - Srirompotong,Ussanee, AU - Newman,Robert W, AU - Lumbiganon,Pagakrong, AU - Wood,John M, Y1 - 2011/02/22/ PY - 2010/10/01/received PY - 2010/12/31/revised PY - 2011/01/27/accepted PY - 2011/2/26/entrez PY - 2011/2/26/pubmed PY - 2011/9/9/medline SP - 3055 EP - 60 JF - Vaccine JO - Vaccine VL - 29 IS - 16 N2 - Influenza vaccination is usually recommended for HIV-infected children. One hundred and twenty seven HIV-infected and twenty-one HIV-uninfected children aged ≥6 months to <18 years, all of whom were naïve to influenza vaccine, were enrolled to receive an influenza Trivalent Inactivated Vaccine (TIV). In the HIV group, the post-vaccination immune response (geometric mean titer, seroconversion and seroprotection rates) correlated with their immunological status before vaccination. The HIV-infected children with no immunosuppression had comparable serological response to HIV-uninfected children. For moderately and severely immunosuppressed HIV groups, two doses of TIV resulted in greater serological responses and should be recommended in these groups. SN - 1873-2518 UR - https://www.unboundmedicine.com/medline/citation/21349365/Serological_response_to_trivalent_inactive_influenza_vaccine_in_HIV_infected_children_with_different_immunologic_status_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(11)00163-0 DB - PRIME DP - Unbound Medicine ER -