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Duration of head-up tilt test for patients with suspected vasovagal syncope.
Europace. 2011 Apr; 13(4):576-80.E

Abstract

AIMS

To investigate the appropriate duration of head-up tilt test (HUTT) needed to induce a positive reaction in patients with suspected vasovagal syncope.

METHODS AND RESULTS

Consecutive patients referred to the syncope unit of our centre for recurrent unexplained syncope were studied. The HUTT included a 30 min passive basic phase and a 20 min sublingual nitroglycerin provocation phase if syncope did not develop during the passive phase. We studied 773 consecutive patients, and 427 (55.2%) patients had a positive HUTT, including 46 patients (10.8%) during the passive basic phase and 381 patients (89.2%) during the nitroglycerin provocation phase. During the basic phase, positive reaction appeared at 7.5 min, and the percentage of positive cases increased with the duration of the test, reaching a peak (20.9%) at 22.5 min, and then decreasing gradually. Most positive reactions (96.1%) occurred between 10 and 25 min during the basic phase. During the nitroglycerin provocation phase, however, the percentage of positive reactions increased rapidly after sublingual nitroglycerin, peaking (35.7%) at 10 min, followed by a sharp decline. Most positive reactions (96.1%) occurred in the first 15 min of the provocation phase.

CONCLUSION

The HUTT was a useful diagnostic test in patients with suspected vasovagal syncope, and sublingual nitroglycerin increased the rate of positive reactions. The appropriate duration for HUTT required at least 25 min during the passive basic phase and 15 min during the nitroglycerin provocation phase.

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Authors+Show Affiliations

Liu J
Cardiac Function Test Center, Peking Union Medical College and Chinese Academy of Medical Sciences, 167 North Lishi Road, Xicheng State, Beijing, 100037 China.
Fang P
No affiliation info available
Liu Y
No affiliation info available
Lu G
No affiliation info available
Li Z
No affiliation info available
Li X
No affiliation info available
Wang Y
No affiliation info available

MeSH

AdolescentAdultAgedChildFemaleHumansMaleMiddle AgedNitroglycerinRetrospective StudiesSyncope, VasovagalTilt-Table TestTime FactorsVasodilator AgentsYoung Adult

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21357590

Citation

Liu, Jun, et al. "Duration of Head-up Tilt Test for Patients With Suspected Vasovagal Syncope." Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology, vol. 13, no. 4, 2011, pp. 576-80.
Liu J, Fang P, Liu Y, et al. Duration of head-up tilt test for patients with suspected vasovagal syncope. Europace. 2011;13(4):576-80.
Liu, J., Fang, P., Liu, Y., Lu, G., Li, Z., Li, X., & Wang, Y. (2011). Duration of head-up tilt test for patients with suspected vasovagal syncope. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology, 13(4), 576-80. https://doi.org/10.1093/europace/eur015
Liu J, et al. Duration of Head-up Tilt Test for Patients With Suspected Vasovagal Syncope. Europace. 2011;13(4):576-80. PubMed PMID: 21357590.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Duration of head-up tilt test for patients with suspected vasovagal syncope. AU - Liu,Jun, AU - Fang,Pihua, AU - Liu,Yue, AU - Lu,Guoying, AU - Li,Zhi, AU - Li,Xiaofeng, AU - Wang,Yushan, Y1 - 2011/02/25/ PY - 2011/3/2/entrez PY - 2011/3/2/pubmed PY - 2011/8/13/medline SP - 576 EP - 80 JF - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology JO - Europace VL - 13 IS - 4 N2 - AIMS: To investigate the appropriate duration of head-up tilt test (HUTT) needed to induce a positive reaction in patients with suspected vasovagal syncope. METHODS AND RESULTS: Consecutive patients referred to the syncope unit of our centre for recurrent unexplained syncope were studied. The HUTT included a 30 min passive basic phase and a 20 min sublingual nitroglycerin provocation phase if syncope did not develop during the passive phase. We studied 773 consecutive patients, and 427 (55.2%) patients had a positive HUTT, including 46 patients (10.8%) during the passive basic phase and 381 patients (89.2%) during the nitroglycerin provocation phase. During the basic phase, positive reaction appeared at 7.5 min, and the percentage of positive cases increased with the duration of the test, reaching a peak (20.9%) at 22.5 min, and then decreasing gradually. Most positive reactions (96.1%) occurred between 10 and 25 min during the basic phase. During the nitroglycerin provocation phase, however, the percentage of positive reactions increased rapidly after sublingual nitroglycerin, peaking (35.7%) at 10 min, followed by a sharp decline. Most positive reactions (96.1%) occurred in the first 15 min of the provocation phase. CONCLUSION: The HUTT was a useful diagnostic test in patients with suspected vasovagal syncope, and sublingual nitroglycerin increased the rate of positive reactions. The appropriate duration for HUTT required at least 25 min during the passive basic phase and 15 min during the nitroglycerin provocation phase. SN - 1532-2092 UR - https://www.unboundmedicine.com/medline/citation/21357590/Duration_of_head_up_tilt_test_for_patients_with_suspected_vasovagal_syncope_ L2 - https://academic.oup.com/europace/article-lookup/doi/10.1093/europace/eur015 DB - PRIME DP - Unbound Medicine ER -