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The concentration distributions of some metabolites in the exhaled breath of young adults.
J Breath Res. 2007 Dec; 1(2):026001.JB

Abstract

The concentrations of ammonia, acetone, methanol, ethanol, propanol and hydrogen cyanide have been measured in the exhaled breath of 26 young adults of age 17/18 years, using selected ion flow tube mass spectrometry (SIFT-MS). Thus the concentration distributions have been constructed and are seen to be essentially log normal with median values in parts per billion (ppb), being ammonia, 317; acetone, 363; methanol, 238; ethanol, 104; propanol, 13; hydrogen cyanide (HCN), 8. There is a clear separation in the median breath ethanol levels between those volunteers who had ingested sugary food/drinks (109 ppb) and those who had not (48 ppb). These data are compared with the results of a study of the same breath compounds, excepting HCN, for a similar sized cohort of healthy volunteers within the age range of 20 to 60 years, which shows that the median levels of these compounds are lower in the young adult volunteer cohort. These HCN measurements are the first to be made in the breath of healthy individuals. The potential implications of these combined results for clinical diagnosis are alluded to.

Authors+Show Affiliations

J Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Dolejškova 3, 182 23, Prague 8, Czech Republic.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21383435

Citation

Spanel, Patrik, et al. "The Concentration Distributions of some Metabolites in the Exhaled Breath of Young Adults." Journal of Breath Research, vol. 1, no. 2, 2007, p. 026001.
Spanel P, Dryahina K, Smith D. The concentration distributions of some metabolites in the exhaled breath of young adults. J Breath Res. 2007;1(2):026001.
Spanel, P., Dryahina, K., & Smith, D. (2007). The concentration distributions of some metabolites in the exhaled breath of young adults. Journal of Breath Research, 1(2), 026001. https://doi.org/10.1088/1752-7155/1/2/026001
Spanel P, Dryahina K, Smith D. The Concentration Distributions of some Metabolites in the Exhaled Breath of Young Adults. J Breath Res. 2007;1(2):026001. PubMed PMID: 21383435.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The concentration distributions of some metabolites in the exhaled breath of young adults. AU - Spanel,Patrik, AU - Dryahina,Kseniya, AU - Smith,David, Y1 - 2007/10/16/ PY - 2011/3/9/entrez PY - 2007/12/1/pubmed PY - 2007/12/1/medline SP - 026001 EP - 026001 JF - Journal of breath research JO - J Breath Res VL - 1 IS - 2 N2 - The concentrations of ammonia, acetone, methanol, ethanol, propanol and hydrogen cyanide have been measured in the exhaled breath of 26 young adults of age 17/18 years, using selected ion flow tube mass spectrometry (SIFT-MS). Thus the concentration distributions have been constructed and are seen to be essentially log normal with median values in parts per billion (ppb), being ammonia, 317; acetone, 363; methanol, 238; ethanol, 104; propanol, 13; hydrogen cyanide (HCN), 8. There is a clear separation in the median breath ethanol levels between those volunteers who had ingested sugary food/drinks (109 ppb) and those who had not (48 ppb). These data are compared with the results of a study of the same breath compounds, excepting HCN, for a similar sized cohort of healthy volunteers within the age range of 20 to 60 years, which shows that the median levels of these compounds are lower in the young adult volunteer cohort. These HCN measurements are the first to be made in the breath of healthy individuals. The potential implications of these combined results for clinical diagnosis are alluded to. SN - 1752-7155 UR - https://www.unboundmedicine.com/medline/citation/21383435/The_concentration_distributions_of_some_metabolites_in_the_exhaled_breath_of_young_adults_ L2 - https://doi.org/10.1088/1752-7155/1/2/026001 DB - PRIME DP - Unbound Medicine ER -
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