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Depressive symptoms and suicide in 56,000 older Chinese: a Hong Kong cohort study.
Soc Psychiatry Psychiatr Epidemiol. 2012 Apr; 47(4):505-14.SP

Abstract

OBJECTIVE

To examine dose-response associations between depressive symptoms and suicide and modification effects of sex, age and health status in older Chinese.

METHODS

We used the Chinese version of the 15-item Geriatric Depression Scale (GDS) to measure depressive symptoms (GDS score ≥ 8) and Cox regression to examine association with suicide mortality in a population-based cohort of 55,946 individuals, aged 65 years or above, enrolled from July 1998 to December 2000 at one of 18 Elderly Health Centres of Hong Kong Department of Health. The cohort was followed up for suicide mortality till 31 March 2009 (mean follow-up 8.7 years).

RESULTS

Depressive symptoms were associated with suicide in men [hazard ratio (HR) 2.03, 95% confidence interval (CI) 0.96-4.29] and women (HR = 2.36, 95% CI 1.31-4.24) after adjusting for age, education, monthly expenditure, smoking, alcohol drinking, physical activity, body mass index, health status, and self-rated health. There was no threshold for GDS score and suicide in either sex. Age, sex and health status did not modify the association.

CONCLUSIONS

Depressive symptoms predict higher suicide risk in older Chinese in a dose-response pattern. These associations were not attenuated by adjustment for health status, suggesting that depressive symptoms in older people are likely to be an independent causal factor for suicide. The GDS score showed no threshold in predicting suicide risk, suggesting that older people with low GDS scores deserve further attention and those with very high scores need urgent intervention.

Authors+Show Affiliations

Department of Community Medicine, School of Public Health, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21384121

Citation

Sun, Wen Jie, et al. "Depressive Symptoms and Suicide in 56,000 Older Chinese: a Hong Kong Cohort Study." Social Psychiatry and Psychiatric Epidemiology, vol. 47, no. 4, 2012, pp. 505-14.
Sun WJ, Xu L, Chan WM, et al. Depressive symptoms and suicide in 56,000 older Chinese: a Hong Kong cohort study. Soc Psychiatry Psychiatr Epidemiol. 2012;47(4):505-14.
Sun, W. J., Xu, L., Chan, W. M., Lam, T. H., & Schooling, C. M. (2012). Depressive symptoms and suicide in 56,000 older Chinese: a Hong Kong cohort study. Social Psychiatry and Psychiatric Epidemiology, 47(4), 505-14. https://doi.org/10.1007/s00127-011-0362-z
Sun WJ, et al. Depressive Symptoms and Suicide in 56,000 Older Chinese: a Hong Kong Cohort Study. Soc Psychiatry Psychiatr Epidemiol. 2012;47(4):505-14. PubMed PMID: 21384121.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Depressive symptoms and suicide in 56,000 older Chinese: a Hong Kong cohort study. AU - Sun,Wen Jie, AU - Xu,Lin, AU - Chan,Wai Man, AU - Lam,Tai Hing, AU - Schooling,C Mary, Y1 - 2011/03/08/ PY - 2010/09/12/received PY - 2011/02/21/accepted PY - 2011/3/9/entrez PY - 2011/3/9/pubmed PY - 2012/9/6/medline SP - 505 EP - 14 JF - Social psychiatry and psychiatric epidemiology JO - Soc Psychiatry Psychiatr Epidemiol VL - 47 IS - 4 N2 - OBJECTIVE: To examine dose-response associations between depressive symptoms and suicide and modification effects of sex, age and health status in older Chinese. METHODS: We used the Chinese version of the 15-item Geriatric Depression Scale (GDS) to measure depressive symptoms (GDS score ≥ 8) and Cox regression to examine association with suicide mortality in a population-based cohort of 55,946 individuals, aged 65 years or above, enrolled from July 1998 to December 2000 at one of 18 Elderly Health Centres of Hong Kong Department of Health. The cohort was followed up for suicide mortality till 31 March 2009 (mean follow-up 8.7 years). RESULTS: Depressive symptoms were associated with suicide in men [hazard ratio (HR) 2.03, 95% confidence interval (CI) 0.96-4.29] and women (HR = 2.36, 95% CI 1.31-4.24) after adjusting for age, education, monthly expenditure, smoking, alcohol drinking, physical activity, body mass index, health status, and self-rated health. There was no threshold for GDS score and suicide in either sex. Age, sex and health status did not modify the association. CONCLUSIONS: Depressive symptoms predict higher suicide risk in older Chinese in a dose-response pattern. These associations were not attenuated by adjustment for health status, suggesting that depressive symptoms in older people are likely to be an independent causal factor for suicide. The GDS score showed no threshold in predicting suicide risk, suggesting that older people with low GDS scores deserve further attention and those with very high scores need urgent intervention. SN - 1433-9285 UR - https://www.unboundmedicine.com/medline/citation/21384121/Depressive_symptoms_and_suicide_in_56000_older_Chinese:_a_Hong_Kong_cohort_study_ L2 - https://dx.doi.org/10.1007/s00127-011-0362-z DB - PRIME DP - Unbound Medicine ER -