Tags

Type your tag names separated by a space and hit enter

Comparison of the rate, location and size of positive surgical margins after laparoscopic and robot-assisted laparoscopic radical prostatectomy.
BJU Int. 2011 Oct; 108(7):1174-8.BI

Abstract

OBJECTIVE

• To review and compare the rate, location and size of positive surgical margins (PSMs) after pure laparoscopic radical prostatectomy (LRP) and robot-assisted laparoscopic radical prostatectomy (RALP).

PATIENTS AND METHODS

• The study comprised 200 patients who underwent RALP and 200 patients who underwent LRP up to January 2008. • We compared patient age, body mass index, preoperative prostate-specific antigen (PSA), preoperative stage and grade, prostate size, pathological stage and grade and neurovascular bundle preservation, as well as PSM rate, size and location. • Continuous and categorical data were compared using Student's t-test and Pearson's chi-squared test. • Multivariate regression analyses were used to identify preoperative and intraoperative predictors of PSMs.

RESULTS

• Although the PSM rate was similar between the two groups (LRP: 12% vs RALP: 13.5%; P = 0.76), location and size were not. PSMs after LRP were mostly at the apex (58.3%; P = 0.038), while most PSMs after RALP were posterolateral ([PL] 48%; P = 0.046). • In addition, the median margin size after RALP was significantly smaller than after LRP (RALP: 2 mm vs LRP: 3.5 mm; P = 0.041). • In univariate and multivariate analyses, tumour-node-metastasis (TNM) stage and preoperative PSA were the only independent preoperative predictors of PSMs (P = 0.044 and P = 0.01, respectively).

CONCLUSION

• The PSM risk is dependent on TNM stage and preoperative PSA and not the surgical technique, when comparing LRP with RALP.

Authors+Show Affiliations

Department of Urology, Institute Montsouris, Paris Descartes University, Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

21392221

Citation

Kasraeian, Ali, et al. "Comparison of the Rate, Location and Size of Positive Surgical Margins After Laparoscopic and Robot-assisted Laparoscopic Radical Prostatectomy." BJU International, vol. 108, no. 7, 2011, pp. 1174-8.
Kasraeian A, Barret E, Chan J, et al. Comparison of the rate, location and size of positive surgical margins after laparoscopic and robot-assisted laparoscopic radical prostatectomy. BJU Int. 2011;108(7):1174-8.
Kasraeian, A., Barret, E., Chan, J., Sanchez-Salas, R., Validire, P., Cathelineau, X., Rozet, F., Galiano, M., & Vallancien, G. (2011). Comparison of the rate, location and size of positive surgical margins after laparoscopic and robot-assisted laparoscopic radical prostatectomy. BJU International, 108(7), 1174-8. https://doi.org/10.1111/j.1464-410X.2010.10077.x
Kasraeian A, et al. Comparison of the Rate, Location and Size of Positive Surgical Margins After Laparoscopic and Robot-assisted Laparoscopic Radical Prostatectomy. BJU Int. 2011;108(7):1174-8. PubMed PMID: 21392221.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of the rate, location and size of positive surgical margins after laparoscopic and robot-assisted laparoscopic radical prostatectomy. AU - Kasraeian,Ali, AU - Barret,Eric, AU - Chan,Jonathan, AU - Sanchez-Salas,Rafael, AU - Validire,Pierre, AU - Cathelineau,Xavier, AU - Rozet,Francois, AU - Galiano,Marc, AU - Vallancien,Guy, Y1 - 2011/03/10/ PY - 2011/3/12/entrez PY - 2011/3/12/pubmed PY - 2011/11/9/medline SP - 1174 EP - 8 JF - BJU international JO - BJU Int VL - 108 IS - 7 N2 - OBJECTIVE: • To review and compare the rate, location and size of positive surgical margins (PSMs) after pure laparoscopic radical prostatectomy (LRP) and robot-assisted laparoscopic radical prostatectomy (RALP). PATIENTS AND METHODS: • The study comprised 200 patients who underwent RALP and 200 patients who underwent LRP up to January 2008. • We compared patient age, body mass index, preoperative prostate-specific antigen (PSA), preoperative stage and grade, prostate size, pathological stage and grade and neurovascular bundle preservation, as well as PSM rate, size and location. • Continuous and categorical data were compared using Student's t-test and Pearson's chi-squared test. • Multivariate regression analyses were used to identify preoperative and intraoperative predictors of PSMs. RESULTS: • Although the PSM rate was similar between the two groups (LRP: 12% vs RALP: 13.5%; P = 0.76), location and size were not. PSMs after LRP were mostly at the apex (58.3%; P = 0.038), while most PSMs after RALP were posterolateral ([PL] 48%; P = 0.046). • In addition, the median margin size after RALP was significantly smaller than after LRP (RALP: 2 mm vs LRP: 3.5 mm; P = 0.041). • In univariate and multivariate analyses, tumour-node-metastasis (TNM) stage and preoperative PSA were the only independent preoperative predictors of PSMs (P = 0.044 and P = 0.01, respectively). CONCLUSION: • The PSM risk is dependent on TNM stage and preoperative PSA and not the surgical technique, when comparing LRP with RALP. SN - 1464-410X UR - https://www.unboundmedicine.com/medline/citation/21392221/Comparison_of_the_rate_location_and_size_of_positive_surgical_margins_after_laparoscopic_and_robot_assisted_laparoscopic_radical_prostatectomy_ L2 - https://doi.org/10.1111/j.1464-410X.2010.10077.x DB - PRIME DP - Unbound Medicine ER -