Tags

Type your tag names separated by a space and hit enter

Cryptococcus gattii infection in a Spanish pet ferret (Mustela putorius furo) and asymptomatic carriage in ferrets and humans from its environment.
Med Mycol. 2011 Oct; 49(7):779-84.MM

Abstract

A domestic ferret (Mustela putorius furo) was presented with lymphadenopathy and acute bilateral blindness. Cytologic evaluation and biopsy of an affected lymph node revealed pyogranulomatous lymphadenitis with intralesional yeast consistent with Cryptococcus sp. Subsequent studies demonstrated Cryptococcus gattii serotype B VGI/AFLP4 as the causative agent. The ferret was treated with fluconazole and prednisone. After one month of therapy, an improvement of the clinical symptoms was detected although blindness persisted. Seven months after presentation, the disease progressed to a severe neurologic condition, and it was euthanized. Postmortem exam revealed disseminated cryptococcosis with prominent neurologic involvement. Nasal swabs of other ferrets and humans from the same household revealed that two ferrets and two humans to be asymptomatic carriers of the same strain of cryptococcus as the necropsied ferret. These findings stress the importance of veterinary diagnostic work with pets and epidemiological investigations for disease prevention in them and in their owners.

Links

Publisher Full Text

Authors+Show Affiliations

Morera N
Clínica Exòtics, Barcelona, Spain. neus_morera@yahoo.es
Juan-Sallés C
No affiliation info available
Torres JM
No affiliation info available
Andreu M
No affiliation info available
Sánchez M
No affiliation info available
Zamora MÁ
No affiliation info available
Colom MF
No affiliation info available

MeSH

Amplified Fragment Length Polymorphism AnalysisAnimalsAnti-Inflammatory AgentsAntifungal AgentsBiopsyBlindnessCarrier StateCryptococcosisCryptococcus gattiiFerretsFluconazoleHumansLymphatic DiseasesMeningitis, CryptococcalMolecular TypingMycological Typing TechniquesPetsPrednisone

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21395475

Citation

Morera, Neus, et al. "Cryptococcus Gattii Infection in a Spanish Pet Ferret (Mustela Putorius Furo) and Asymptomatic Carriage in Ferrets and Humans From Its Environment." Medical Mycology, vol. 49, no. 7, 2011, pp. 779-84.
Morera N, Juan-Sallés C, Torres JM, et al. Cryptococcus gattii infection in a Spanish pet ferret (Mustela putorius furo) and asymptomatic carriage in ferrets and humans from its environment. Med Mycol. 2011;49(7):779-84.
Morera, N., Juan-Sallés, C., Torres, J. M., Andreu, M., Sánchez, M., Zamora, M. Á., & Colom, M. F. (2011). Cryptococcus gattii infection in a Spanish pet ferret (Mustela putorius furo) and asymptomatic carriage in ferrets and humans from its environment. Medical Mycology, 49(7), 779-84. https://doi.org/10.3109/13693786.2011.564216
Morera N, et al. Cryptococcus Gattii Infection in a Spanish Pet Ferret (Mustela Putorius Furo) and Asymptomatic Carriage in Ferrets and Humans From Its Environment. Med Mycol. 2011;49(7):779-84. PubMed PMID: 21395475.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cryptococcus gattii infection in a Spanish pet ferret (Mustela putorius furo) and asymptomatic carriage in ferrets and humans from its environment. AU - Morera,Neus, AU - Juan-Sallés,Carles, AU - Torres,Josep M, AU - Andreu,Mariano, AU - Sánchez,Manuel, AU - Zamora,María Ángeles, AU - Colom,M Francisca, Y1 - 2011/03/14/ PY - 2011/3/15/entrez PY - 2011/3/15/pubmed PY - 2012/1/11/medline SP - 779 EP - 84 JF - Medical mycology JO - Med Mycol VL - 49 IS - 7 N2 - A domestic ferret (Mustela putorius furo) was presented with lymphadenopathy and acute bilateral blindness. Cytologic evaluation and biopsy of an affected lymph node revealed pyogranulomatous lymphadenitis with intralesional yeast consistent with Cryptococcus sp. Subsequent studies demonstrated Cryptococcus gattii serotype B VGI/AFLP4 as the causative agent. The ferret was treated with fluconazole and prednisone. After one month of therapy, an improvement of the clinical symptoms was detected although blindness persisted. Seven months after presentation, the disease progressed to a severe neurologic condition, and it was euthanized. Postmortem exam revealed disseminated cryptococcosis with prominent neurologic involvement. Nasal swabs of other ferrets and humans from the same household revealed that two ferrets and two humans to be asymptomatic carriers of the same strain of cryptococcus as the necropsied ferret. These findings stress the importance of veterinary diagnostic work with pets and epidemiological investigations for disease prevention in them and in their owners. SN - 1460-2709 UR - https://www.unboundmedicine.com/medline/citation/21395475/Cryptococcus_gattii_infection_in_a_Spanish_pet_ferret__Mustela_putorius_furo__and_asymptomatic_carriage_in_ferrets_and_humans_from_its_environment_ L2 - https://academic.oup.com/mmy/article-lookup/doi/10.3109/13693786.2011.564216 DB - PRIME DP - Unbound Medicine ER -