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Interactive effect of body posture on exercise-induced atrial natriuretic peptide release.
Am J Physiol. 1990 May; 258(5 Pt 1):E775-9.AJ

Abstract

The purpose of this investigation was to test the hypothesis that supine exercise elicits a greater atrial natriuretic peptide (ANP) response than upright exercise because of higher atrial filling pressure attained in the supine posture. Plasma ANP concentration ([ANP]) was measured during continuous graded supine and upright exercise in eight healthy men at rest after 4 min of cycling exercise at 31, 51, and 79% of posture-specific peak oxygen uptake (VO2 peak), after 2 min of cycling at posture-specific VO2 peak, and 5 and 15 min postexercise. [ANP] was significantly increased (P less than 0.05) above rest by 64, 140, and 228% during supine cycling at 51 and 79% and VO2 peak, respectively. During upright cycling, [ANP] was significantly increased (P less than 0.05) at 79% (60%) and VO2 peak (125%). After 15 min of postexercise rest, [ANP] remained elevated (P less than 0.05) only in the supine subjects. [ANP] was 63, 79, and 75% higher (P less than 0.05) in the supine than in the upright position during cycling at 51 and 79% and VO2 peak. Systolic, diastolic, and mean blood pressures were not significantly (P greater than 0.05) different between positions in all measurement periods. Heart rates were lower (P less than 0.05) in the supine position compared with the upright position. In conclusion, these results suggest that supine exercise elicits greater ANP release independent of blood pressure and heart rate but presumably caused by greater venous return, central blood volume, and concomitant atrial filling pressure and stretch.

Authors+Show Affiliations

Department of Physical Education, University of Georgia, Athens 30602.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2139763

Citation

Ray, C A., et al. "Interactive Effect of Body Posture On Exercise-induced Atrial Natriuretic Peptide Release." The American Journal of Physiology, vol. 258, no. 5 Pt 1, 1990, pp. E775-9.
Ray CA, Delp MD, Hartle DK. Interactive effect of body posture on exercise-induced atrial natriuretic peptide release. Am J Physiol. 1990;258(5 Pt 1):E775-9.
Ray, C. A., Delp, M. D., & Hartle, D. K. (1990). Interactive effect of body posture on exercise-induced atrial natriuretic peptide release. The American Journal of Physiology, 258(5 Pt 1), E775-9.
Ray CA, Delp MD, Hartle DK. Interactive Effect of Body Posture On Exercise-induced Atrial Natriuretic Peptide Release. Am J Physiol. 1990;258(5 Pt 1):E775-9. PubMed PMID: 2139763.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Interactive effect of body posture on exercise-induced atrial natriuretic peptide release. AU - Ray,C A, AU - Delp,M D, AU - Hartle,D K, PY - 1990/5/1/pubmed PY - 1990/5/1/medline PY - 1990/5/1/entrez SP - E775 EP - 9 JF - The American journal of physiology JO - Am J Physiol VL - 258 IS - 5 Pt 1 N2 - The purpose of this investigation was to test the hypothesis that supine exercise elicits a greater atrial natriuretic peptide (ANP) response than upright exercise because of higher atrial filling pressure attained in the supine posture. Plasma ANP concentration ([ANP]) was measured during continuous graded supine and upright exercise in eight healthy men at rest after 4 min of cycling exercise at 31, 51, and 79% of posture-specific peak oxygen uptake (VO2 peak), after 2 min of cycling at posture-specific VO2 peak, and 5 and 15 min postexercise. [ANP] was significantly increased (P less than 0.05) above rest by 64, 140, and 228% during supine cycling at 51 and 79% and VO2 peak, respectively. During upright cycling, [ANP] was significantly increased (P less than 0.05) at 79% (60%) and VO2 peak (125%). After 15 min of postexercise rest, [ANP] remained elevated (P less than 0.05) only in the supine subjects. [ANP] was 63, 79, and 75% higher (P less than 0.05) in the supine than in the upright position during cycling at 51 and 79% and VO2 peak. Systolic, diastolic, and mean blood pressures were not significantly (P greater than 0.05) different between positions in all measurement periods. Heart rates were lower (P less than 0.05) in the supine position compared with the upright position. In conclusion, these results suggest that supine exercise elicits greater ANP release independent of blood pressure and heart rate but presumably caused by greater venous return, central blood volume, and concomitant atrial filling pressure and stretch. SN - 0002-9513 UR - https://www.unboundmedicine.com/medline/citation/2139763/Interactive_effect_of_body_posture_on_exercise_induced_atrial_natriuretic_peptide_release_ L2 - https://journals.physiology.org/doi/10.1152/ajpendo.1990.258.5.E775?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -