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Organocatalytic chemoselective asymmetric N-allylic alkylation of enamides.
Chem Commun (Camb). 2011 Apr 28; 47(16):4784-6.CC

Abstract

The first Lewis base-catalysed chemoselective asymmetric N-allylic alkylation of enamides with Morita-Baylis-Hillman carbonates has been developed, which affords multifunctional products in moderate to high enantioselectivity (up to 92% ee).

Authors+Show Affiliations

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21409282

Citation

Huang, Ji-Rong, et al. "Organocatalytic Chemoselective Asymmetric N-allylic Alkylation of Enamides." Chemical Communications (Cambridge, England), vol. 47, no. 16, 2011, pp. 4784-6.
Huang JR, Cui HL, Lei J, et al. Organocatalytic chemoselective asymmetric N-allylic alkylation of enamides. Chem Commun (Camb). 2011;47(16):4784-6.
Huang, J. R., Cui, H. L., Lei, J., Sun, X. H., & Chen, Y. C. (2011). Organocatalytic chemoselective asymmetric N-allylic alkylation of enamides. Chemical Communications (Cambridge, England), 47(16), 4784-6. https://doi.org/10.1039/c0cc05616b
Huang JR, et al. Organocatalytic Chemoselective Asymmetric N-allylic Alkylation of Enamides. Chem Commun (Camb). 2011 Apr 28;47(16):4784-6. PubMed PMID: 21409282.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Organocatalytic chemoselective asymmetric N-allylic alkylation of enamides. AU - Huang,Ji-Rong, AU - Cui,Hai-Lei, AU - Lei,Jie, AU - Sun,Xun-Hao, AU - Chen,Ying-Chun, Y1 - 2011/03/16/ PY - 2011/3/17/entrez PY - 2011/3/17/pubmed PY - 2011/7/29/medline SP - 4784 EP - 6 JF - Chemical communications (Cambridge, England) JO - Chem Commun (Camb) VL - 47 IS - 16 N2 - The first Lewis base-catalysed chemoselective asymmetric N-allylic alkylation of enamides with Morita-Baylis-Hillman carbonates has been developed, which affords multifunctional products in moderate to high enantioselectivity (up to 92% ee). SN - 1364-548X UR - https://www.unboundmedicine.com/medline/citation/21409282/Organocatalytic_chemoselective_asymmetric_N_allylic_alkylation_of_enamides_ L2 - https://doi.org/10.1039/c0cc05616b DB - PRIME DP - Unbound Medicine ER -