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Update on AUA guideline on the management of benign prostatic hyperplasia.
J Urol 2011; 185(5):1793-803JU

Abstract

PURPOSE

To revise the 2003 version of the American Urological Association's (AUA) Guideline on the management of benign prostatic hyperplasia (BPH).

MATERIALS AND METHODS

From MEDLINE® searches of English language publications (January 1999 through February 2008) using relevant MeSH terms, articles concerning the management of the index patient, a male ≥45 years of age who is consulting a healthcare provider for lower urinary tract symptoms (LUTS) were identified. Qualitative analysis of the evidence was performed. Selected studies were stratified by design, comparator, follow-up interval, and intensity of intervention, and meta-analyses (quantitative synthesis) of outcomes of randomized controlled trials were planned. Guideline statements were drafted by an appointed expert Panel based on the evidence.

RESULTS

The studies varied as to patient selection; randomization; blinding mechanism; run-in periods; patient demographics, comorbidities, prostate characteristics and symptoms; drug doses; other intervention characteristics; comparators; rigor and intervals of follow-up; trial duration and timing; suspected lack of applicability to current US practice; and techniques of outcomes measurement. These variations affected the quality of the evidence reviewed making formal meta-analysis impractical or futile. Instead, the Panel and extractors reviewed the data in a systematic fashion and without statistical rigor. Diagnosis and treatment algorithms were adopted from the 2005 International Consultation of Urologic Diseases. Guideline statements concerning pharmacotherapies, watchful waiting, surgical options and minimally invasive procedures were either updated or newly drafted, peer reviewed and approved by AUA Board of Directors.

CONCLUSIONS

New pharmacotherapies and technologies have emerged which have impacted treatment algorithms. The management of LUTS/BPH continues to evolve.

Authors+Show Affiliations

American Urological Association Education and Research, Inc., Linthicum Maryland, USA. k-mcvary@northwestern.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21420124

Citation

McVary, Kevin T., et al. "Update On AUA Guideline On the Management of Benign Prostatic Hyperplasia." The Journal of Urology, vol. 185, no. 5, 2011, pp. 1793-803.
McVary KT, Roehrborn CG, Avins AL, et al. Update on AUA guideline on the management of benign prostatic hyperplasia. J Urol. 2011;185(5):1793-803.
McVary, K. T., Roehrborn, C. G., Avins, A. L., Barry, M. J., Bruskewitz, R. C., Donnell, R. F., ... Wei, J. T. (2011). Update on AUA guideline on the management of benign prostatic hyperplasia. The Journal of Urology, 185(5), pp. 1793-803. doi:10.1016/j.juro.2011.01.074.
McVary KT, et al. Update On AUA Guideline On the Management of Benign Prostatic Hyperplasia. J Urol. 2011;185(5):1793-803. PubMed PMID: 21420124.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Update on AUA guideline on the management of benign prostatic hyperplasia. AU - McVary,Kevin T, AU - Roehrborn,Claus G, AU - Avins,Andrew L, AU - Barry,Michael J, AU - Bruskewitz,Reginald C, AU - Donnell,Robert F, AU - Foster,Harris E,Jr AU - Gonzalez,Chris M, AU - Kaplan,Steven A, AU - Penson,David F, AU - Ulchaker,James C, AU - Wei,John T, Y1 - 2011/03/21/ PY - 2011/3/23/entrez PY - 2011/3/23/pubmed PY - 2011/6/29/medline SP - 1793 EP - 803 JF - The Journal of urology JO - J. Urol. VL - 185 IS - 5 N2 - PURPOSE: To revise the 2003 version of the American Urological Association's (AUA) Guideline on the management of benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: From MEDLINE® searches of English language publications (January 1999 through February 2008) using relevant MeSH terms, articles concerning the management of the index patient, a male ≥45 years of age who is consulting a healthcare provider for lower urinary tract symptoms (LUTS) were identified. Qualitative analysis of the evidence was performed. Selected studies were stratified by design, comparator, follow-up interval, and intensity of intervention, and meta-analyses (quantitative synthesis) of outcomes of randomized controlled trials were planned. Guideline statements were drafted by an appointed expert Panel based on the evidence. RESULTS: The studies varied as to patient selection; randomization; blinding mechanism; run-in periods; patient demographics, comorbidities, prostate characteristics and symptoms; drug doses; other intervention characteristics; comparators; rigor and intervals of follow-up; trial duration and timing; suspected lack of applicability to current US practice; and techniques of outcomes measurement. These variations affected the quality of the evidence reviewed making formal meta-analysis impractical or futile. Instead, the Panel and extractors reviewed the data in a systematic fashion and without statistical rigor. Diagnosis and treatment algorithms were adopted from the 2005 International Consultation of Urologic Diseases. Guideline statements concerning pharmacotherapies, watchful waiting, surgical options and minimally invasive procedures were either updated or newly drafted, peer reviewed and approved by AUA Board of Directors. CONCLUSIONS: New pharmacotherapies and technologies have emerged which have impacted treatment algorithms. The management of LUTS/BPH continues to evolve. SN - 1527-3792 UR - http://www.unboundmedicine.com/medline/citation/21420124/full_citation L2 - https://www.jurology.com/doi/full/10.1016/j.juro.2011.01.074?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -