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Egg consumption and risk of cardiovascular disease in the SUN Project.
Eur J Clin Nutr. 2011 Jun; 65(6):676-82.EJ

Abstract

BACKGROUND/OBJECTIVES

Egg consumption has been associated with the risk of cardiovascular diseases (CVDs), but evidence is scarce and inconsistent. Our aim was to examine the association between egg consumption and incidence of CVD in a prospective dynamic Mediterranean cohort of 14,185 university graduates.

SUBJECTS/METHODS

Egg intake was assessed using a 136-item-validated food-frequency questionnaire. Baseline consumption was categorized into no consumption or <1 egg/week, 1 egg/week, 2-4 eggs/week and >4 eggs/week. The presence of cardiovascular risk factors was assessed by questionnaire at baseline, and the incidence of CVD was assessed using biennial assessments. The median follow-up was 6.1 years. Cox regression models were fitted to estimate multivariable-adjusted hazard ratios (HRs) for CVD (myocardial infarction, revascularization procedures or stroke). Outcomes were confirmed by review of medical records.

RESULTS

During a median follow-up of 6.1 years, 91 new confirmed cases of CVD were observed. No association was found between egg consumption and the incidence of CVD (HR: 1.10, 95% confidence interval: 0.46-2.63) for the highest versus the lowest category of egg consumption after adjusting for age, sex, total energy intake, adherence to the Mediterranean food pattern and other cardiovascular risk factors. Results were robust to different analytical scenarios.

CONCLUSIONS

No association between egg consumption and the incidence of CVD was found in this Mediterranean cohort.

Authors+Show Affiliations

Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21427738

Citation

Zazpe, I, et al. "Egg Consumption and Risk of Cardiovascular Disease in the SUN Project." European Journal of Clinical Nutrition, vol. 65, no. 6, 2011, pp. 676-82.
Zazpe I, Beunza JJ, Bes-Rastrollo M, et al. Egg consumption and risk of cardiovascular disease in the SUN Project. Eur J Clin Nutr. 2011;65(6):676-82.
Zazpe, I., Beunza, J. J., Bes-Rastrollo, M., Warnberg, J., de la Fuente-Arrillaga, C., Benito, S., Vázquez, Z., & Martínez-González, M. A. (2011). Egg consumption and risk of cardiovascular disease in the SUN Project. European Journal of Clinical Nutrition, 65(6), 676-82. https://doi.org/10.1038/ejcn.2011.30
Zazpe I, et al. Egg Consumption and Risk of Cardiovascular Disease in the SUN Project. Eur J Clin Nutr. 2011;65(6):676-82. PubMed PMID: 21427738.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Egg consumption and risk of cardiovascular disease in the SUN Project. AU - Zazpe,I, AU - Beunza,J J, AU - Bes-Rastrollo,M, AU - Warnberg,J, AU - de la Fuente-Arrillaga,C, AU - Benito,S, AU - Vázquez,Z, AU - Martínez-González,M A, AU - ,, Y1 - 2011/03/23/ PY - 2011/3/24/entrez PY - 2011/3/24/pubmed PY - 2011/12/14/medline SP - 676 EP - 82 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 65 IS - 6 N2 - BACKGROUND/OBJECTIVES: Egg consumption has been associated with the risk of cardiovascular diseases (CVDs), but evidence is scarce and inconsistent. Our aim was to examine the association between egg consumption and incidence of CVD in a prospective dynamic Mediterranean cohort of 14,185 university graduates. SUBJECTS/METHODS: Egg intake was assessed using a 136-item-validated food-frequency questionnaire. Baseline consumption was categorized into no consumption or <1 egg/week, 1 egg/week, 2-4 eggs/week and >4 eggs/week. The presence of cardiovascular risk factors was assessed by questionnaire at baseline, and the incidence of CVD was assessed using biennial assessments. The median follow-up was 6.1 years. Cox regression models were fitted to estimate multivariable-adjusted hazard ratios (HRs) for CVD (myocardial infarction, revascularization procedures or stroke). Outcomes were confirmed by review of medical records. RESULTS: During a median follow-up of 6.1 years, 91 new confirmed cases of CVD were observed. No association was found between egg consumption and the incidence of CVD (HR: 1.10, 95% confidence interval: 0.46-2.63) for the highest versus the lowest category of egg consumption after adjusting for age, sex, total energy intake, adherence to the Mediterranean food pattern and other cardiovascular risk factors. Results were robust to different analytical scenarios. CONCLUSIONS: No association between egg consumption and the incidence of CVD was found in this Mediterranean cohort. SN - 1476-5640 UR - https://www.unboundmedicine.com/medline/citation/21427738/Egg_consumption_and_risk_of_cardiovascular_disease_in_the_SUN_Project_ L2 - https://doi.org/10.1038/ejcn.2011.30 DB - PRIME DP - Unbound Medicine ER -