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Subthreshold depression in Parkinson's disease.
Mov Disord. 2011 Aug 01; 26(9):1741-4.MD

Abstract

BACKGROUND

Quality of life in Parkinson patients with subthreshold depression could be improved if the prevalence and symptom profile were better understood.

METHODS

Our study used standard DSM-IV and Judd criteria as well as motor, depression, and quality-of-life scales to investigate a sample of 110 nondemented Parkinson patients. This led to formation of nondepressed (48.2%), subthreshold depressed (25.5%), and depressed (26.4%) groups.

RESULTS

Quality of life was seen to be significantly lower in subthreshold depressed patients than in the nondepressed, and there were differences in the frequency of depressive symptoms that partially overlapped with nonmotor symptoms of vegetative origin in Parkinson's disease (appetite, sleep disorders). Key measures of depression (diminished interest/pleasure) were more frequent in the depressed group compared with the subthreshold depressed, although the motor functions of these 2 groups did not differ significantly.

CONCLUSIONS

The Beck Depression Inventory score ranging from 9 to 15 points differentiates subthreshold depressed from nondepressed and depressed patients best.

Authors+Show Affiliations

Department of Psychiatry, Zentrum für Integrative Psychiatrie, Kiel, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21442660

Citation

Reiff, Julia, et al. "Subthreshold Depression in Parkinson's Disease." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 26, no. 9, 2011, pp. 1741-4.
Reiff J, Schmidt N, Riebe B, et al. Subthreshold depression in Parkinson's disease. Mov Disord. 2011;26(9):1741-4.
Reiff, J., Schmidt, N., Riebe, B., Breternitz, R., Aldenhoff, J., Deuschl, G., & Witt, K. (2011). Subthreshold depression in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society, 26(9), 1741-4. https://doi.org/10.1002/mds.23699
Reiff J, et al. Subthreshold Depression in Parkinson's Disease. Mov Disord. 2011 Aug 1;26(9):1741-4. PubMed PMID: 21442660.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Subthreshold depression in Parkinson's disease. AU - Reiff,Julia, AU - Schmidt,Nele, AU - Riebe,Bastian, AU - Breternitz,Robert, AU - Aldenhoff,Josef, AU - Deuschl,Günther, AU - Witt,Karsten, Y1 - 2011/03/25/ PY - 2009/12/30/received PY - 2011/01/10/revised PY - 2011/02/07/accepted PY - 2011/3/29/entrez PY - 2011/3/29/pubmed PY - 2011/12/13/medline SP - 1741 EP - 4 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 26 IS - 9 N2 - BACKGROUND: Quality of life in Parkinson patients with subthreshold depression could be improved if the prevalence and symptom profile were better understood. METHODS: Our study used standard DSM-IV and Judd criteria as well as motor, depression, and quality-of-life scales to investigate a sample of 110 nondemented Parkinson patients. This led to formation of nondepressed (48.2%), subthreshold depressed (25.5%), and depressed (26.4%) groups. RESULTS: Quality of life was seen to be significantly lower in subthreshold depressed patients than in the nondepressed, and there were differences in the frequency of depressive symptoms that partially overlapped with nonmotor symptoms of vegetative origin in Parkinson's disease (appetite, sleep disorders). Key measures of depression (diminished interest/pleasure) were more frequent in the depressed group compared with the subthreshold depressed, although the motor functions of these 2 groups did not differ significantly. CONCLUSIONS: The Beck Depression Inventory score ranging from 9 to 15 points differentiates subthreshold depressed from nondepressed and depressed patients best. SN - 1531-8257 UR - https://www.unboundmedicine.com/medline/citation/21442660/Subthreshold_depression_in_Parkinson's_disease_ L2 - https://doi.org/10.1002/mds.23699 DB - PRIME DP - Unbound Medicine ER -