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Hepatitis E virus infection in developed countries.
Virus Res. 2011 Oct; 161(1):40-6.VR

Abstract

Hepatitis E was considered to be endemic infectious disease in developing countries in tropical or subtropical regions with poor sanitary conditions. Large, previously reported outbreaks were mainly due to contaminated water or heavy flooding. Prototype hepatitis E viruses of genotypes I and II were obtained from such endemic cases. In developed countries, in contrast, hepatitis E was rare and diagnosed only in travelers or imported cases. However, the development of accurate diagnostic tests, mainly PCR detection elucidated that autochthonous hepatitis E in developed countries is far more common than previously thought. Although the main route of transmission is food-borne, other routes including blood-borne have been suggested. Recent developments of gene-based diagnostic assays and molecular epidemiology have disclosed the significance of hepatitis E virus infection in developed countries.

Authors+Show Affiliations

National Institute of Infectious Diseases, Tokyo, Japan. tmiyam@nih.go.jp

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21443914

Citation

Miyamura, Tatsuo. "Hepatitis E Virus Infection in Developed Countries." Virus Research, vol. 161, no. 1, 2011, pp. 40-6.
Miyamura T. Hepatitis E virus infection in developed countries. Virus Res. 2011;161(1):40-6.
Miyamura, T. (2011). Hepatitis E virus infection in developed countries. Virus Research, 161(1), 40-6. https://doi.org/10.1016/j.virusres.2011.03.006
Miyamura T. Hepatitis E Virus Infection in Developed Countries. Virus Res. 2011;161(1):40-6. PubMed PMID: 21443914.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hepatitis E virus infection in developed countries. A1 - Miyamura,Tatsuo, Y1 - 2011/04/02/ PY - 2010/12/08/received PY - 2011/03/01/revised PY - 2011/03/06/accepted PY - 2011/3/30/entrez PY - 2011/3/30/pubmed PY - 2012/1/5/medline SP - 40 EP - 6 JF - Virus research JO - Virus Res VL - 161 IS - 1 N2 - Hepatitis E was considered to be endemic infectious disease in developing countries in tropical or subtropical regions with poor sanitary conditions. Large, previously reported outbreaks were mainly due to contaminated water or heavy flooding. Prototype hepatitis E viruses of genotypes I and II were obtained from such endemic cases. In developed countries, in contrast, hepatitis E was rare and diagnosed only in travelers or imported cases. However, the development of accurate diagnostic tests, mainly PCR detection elucidated that autochthonous hepatitis E in developed countries is far more common than previously thought. Although the main route of transmission is food-borne, other routes including blood-borne have been suggested. Recent developments of gene-based diagnostic assays and molecular epidemiology have disclosed the significance of hepatitis E virus infection in developed countries. SN - 1872-7492 UR - https://www.unboundmedicine.com/medline/citation/21443914/Hepatitis_E_virus_infection_in_developed_countries_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0168-1702(11)00078-5 DB - PRIME DP - Unbound Medicine ER -
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