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Human papilloma virus screening by hybrid capture II in Chinese women of Jiangsu Province.
West Indian Med J. 2010 Oct; 59(5):469-72.WI

Abstract

OBJECTIVE

To survey Human Papilloma Virus (HPV) infection in Chinese Women of Jiangsu Province and discuss the relationship between HPV and the biology of cervical cancer.

METHODS

Two thousand, one hundred and fifty-three sexually active women (including 66 cases of cervical cancer) were selected for high-risk human papilloma virus DNA test with Hybrid Capture II (HCII).

RESULTS

The overall HPV prevalence was 32.6% (701/2153) with higher positive rates in cervical carcinoma and Cervical Interstitial Neoplasia (CIN) [93.9% and 54.6%] respectively. For women aged 40-59 years, the overall high-risk HPV prevalence was higher than those of other age groups. Compared with CIN I, the positivity rate and viral load of HPV DNA in CIN III is much higher (80.2% vs. 29.9%, 11.89 vs. 0.53). Ninety-four per cent (64/66) of patients with Cervical cancer were detected to be HPV positive. There was no significant difference in HPV DNA among each clinical stage and pathologic grade. But the positive rates and the value of HPV DNA were higher in the patients with cervical interstitial incursion. Eighty per cent of patients (20/25) could become negative within six months after operation.

CONCLUSIONS

High-risk HPV DNA test is effective in screening for cervical diseases. HCII is an effective method to detect HPV DNA.

Authors+Show Affiliations

Changzhou Woman and Children Health Hospital, Changzhou 213003, Jiangsu Province, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21473391

Citation

Wang, Q W., et al. "Human Papilloma Virus Screening By Hybrid Capture II in Chinese Women of Jiangsu Province." The West Indian Medical Journal, vol. 59, no. 5, 2010, pp. 469-72.
Wang QW, Xu PZ, Zhang B, et al. Human papilloma virus screening by hybrid capture II in Chinese women of Jiangsu Province. West Indian Med J. 2010;59(5):469-72.
Wang, Q. W., Xu, P. Z., Zhang, B., Dong, Y. S., Yang, Y. Q., Cao, F., & Yu, B. (2010). Human papilloma virus screening by hybrid capture II in Chinese women of Jiangsu Province. The West Indian Medical Journal, 59(5), 469-72.
Wang QW, et al. Human Papilloma Virus Screening By Hybrid Capture II in Chinese Women of Jiangsu Province. West Indian Med J. 2010;59(5):469-72. PubMed PMID: 21473391.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Human papilloma virus screening by hybrid capture II in Chinese women of Jiangsu Province. AU - Wang,Q W, AU - Xu,P Z, AU - Zhang,B, AU - Dong,Y S, AU - Yang,Y Q, AU - Cao,F, AU - Yu,B, PY - 2011/4/9/entrez PY - 2011/4/9/pubmed PY - 2011/6/22/medline SP - 469 EP - 72 JF - The West Indian medical journal JO - West Indian Med J VL - 59 IS - 5 N2 - OBJECTIVE: To survey Human Papilloma Virus (HPV) infection in Chinese Women of Jiangsu Province and discuss the relationship between HPV and the biology of cervical cancer. METHODS: Two thousand, one hundred and fifty-three sexually active women (including 66 cases of cervical cancer) were selected for high-risk human papilloma virus DNA test with Hybrid Capture II (HCII). RESULTS: The overall HPV prevalence was 32.6% (701/2153) with higher positive rates in cervical carcinoma and Cervical Interstitial Neoplasia (CIN) [93.9% and 54.6%] respectively. For women aged 40-59 years, the overall high-risk HPV prevalence was higher than those of other age groups. Compared with CIN I, the positivity rate and viral load of HPV DNA in CIN III is much higher (80.2% vs. 29.9%, 11.89 vs. 0.53). Ninety-four per cent (64/66) of patients with Cervical cancer were detected to be HPV positive. There was no significant difference in HPV DNA among each clinical stage and pathologic grade. But the positive rates and the value of HPV DNA were higher in the patients with cervical interstitial incursion. Eighty per cent of patients (20/25) could become negative within six months after operation. CONCLUSIONS: High-risk HPV DNA test is effective in screening for cervical diseases. HCII is an effective method to detect HPV DNA. SN - 0043-3144 UR - https://www.unboundmedicine.com/medline/citation/21473391/Human_papilloma_virus_screening_by_hybrid_capture_II_in_Chinese_women_of_Jiangsu_Province_ L2 - https://screening.iarc.fr/viavili.php DB - PRIME DP - Unbound Medicine ER -