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Anthropometric, clinical and laboratory comparison of four phenotypes of polycystic ovary syndrome based on Rotterdam criteria.
J Obstet Gynaecol Res. 2011 Aug; 37(8):1020-6.JO

Abstract

AIM

To compare all phenotypes of polycystic ovary syndrome (PCOS) for anthropometrical, hormonal, and metabolic differences according to Rotterdam criteria.

MATERIAL & METHODS

Women with PCOS (Rotterdam definition; n = 127) and women without PCOS used as controls (n = 44). There were four phenotypes of PCOS: 56/127 (44.09%) of the patients were polycystic ovaries on ultrasound (PCO) + oligo or anovulation (O) + biochemical and/or clinical hyperandrogenism (HA), 29/127 (22.84%) were HA+O, 24/127 (18.90%) were PCO+O and 18/127 (14.17%) were HA+PCO. And 42/127 (33.07%) patients represented the new phenotypes (PCO+O and HA+PCO). Phenotypical, hormonal and metabolic parameters were compared between the groups.

RESULTS

Waist-to-hip ratio, luteinizing hormone-to-follicle stimulating hormone ratio, testosterone, androstenedione, dehydroepiandrostenedione were lower in women with PCO+O and controls than the other three phenotypes. The highest score regarding hirsutismus was found in the HA+O phenotype and the lowest score in the PCO+O phenotype. Prevalence of metabolic syndrome and degree of insulin resistance in PCO+O phenotype was closer to control subjects than the other three phenotypes.

CONCLUSIONS

Anthropometrical, hormonal, and metabolic differences suggest that PCO+O phenotype is closer to control group than the other PCOS phenotypes.

Authors+Show Affiliations

Nenehatun Obstetrics and Gynecology Hospital, Erzurum, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

21481088

Citation

Yilmaz, Mehmet, et al. "Anthropometric, Clinical and Laboratory Comparison of Four Phenotypes of Polycystic Ovary Syndrome Based On Rotterdam Criteria." The Journal of Obstetrics and Gynaecology Research, vol. 37, no. 8, 2011, pp. 1020-6.
Yilmaz M, Isaoglu U, Delibas IB, et al. Anthropometric, clinical and laboratory comparison of four phenotypes of polycystic ovary syndrome based on Rotterdam criteria. J Obstet Gynaecol Res. 2011;37(8):1020-6.
Yilmaz, M., Isaoglu, U., Delibas, I. B., & Kadanali, S. (2011). Anthropometric, clinical and laboratory comparison of four phenotypes of polycystic ovary syndrome based on Rotterdam criteria. The Journal of Obstetrics and Gynaecology Research, 37(8), 1020-6. https://doi.org/10.1111/j.1447-0756.2010.01478.x
Yilmaz M, et al. Anthropometric, Clinical and Laboratory Comparison of Four Phenotypes of Polycystic Ovary Syndrome Based On Rotterdam Criteria. J Obstet Gynaecol Res. 2011;37(8):1020-6. PubMed PMID: 21481088.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anthropometric, clinical and laboratory comparison of four phenotypes of polycystic ovary syndrome based on Rotterdam criteria. AU - Yilmaz,Mehmet, AU - Isaoglu,Unal, AU - Delibas,Ilhan Bahri, AU - Kadanali,Sedat, Y1 - 2011/04/12/ PY - 2011/4/13/entrez PY - 2011/4/13/pubmed PY - 2012/1/21/medline SP - 1020 EP - 6 JF - The journal of obstetrics and gynaecology research JO - J Obstet Gynaecol Res VL - 37 IS - 8 N2 - AIM: To compare all phenotypes of polycystic ovary syndrome (PCOS) for anthropometrical, hormonal, and metabolic differences according to Rotterdam criteria. MATERIAL & METHODS: Women with PCOS (Rotterdam definition; n = 127) and women without PCOS used as controls (n = 44). There were four phenotypes of PCOS: 56/127 (44.09%) of the patients were polycystic ovaries on ultrasound (PCO) + oligo or anovulation (O) + biochemical and/or clinical hyperandrogenism (HA), 29/127 (22.84%) were HA+O, 24/127 (18.90%) were PCO+O and 18/127 (14.17%) were HA+PCO. And 42/127 (33.07%) patients represented the new phenotypes (PCO+O and HA+PCO). Phenotypical, hormonal and metabolic parameters were compared between the groups. RESULTS: Waist-to-hip ratio, luteinizing hormone-to-follicle stimulating hormone ratio, testosterone, androstenedione, dehydroepiandrostenedione were lower in women with PCO+O and controls than the other three phenotypes. The highest score regarding hirsutismus was found in the HA+O phenotype and the lowest score in the PCO+O phenotype. Prevalence of metabolic syndrome and degree of insulin resistance in PCO+O phenotype was closer to control subjects than the other three phenotypes. CONCLUSIONS: Anthropometrical, hormonal, and metabolic differences suggest that PCO+O phenotype is closer to control group than the other PCOS phenotypes. SN - 1447-0756 UR - https://www.unboundmedicine.com/medline/citation/21481088/Anthropometric_clinical_and_laboratory_comparison_of_four_phenotypes_of_polycystic_ovary_syndrome_based_on_Rotterdam_criteria_ L2 - https://doi.org/10.1111/j.1447-0756.2010.01478.x DB - PRIME DP - Unbound Medicine ER -