Tags

Type your tag names separated by a space and hit enter

Association of serum ferritin with metabolic syndrome and diabetes mellitus in the South Korean general population according to the Korean National Health and Nutrition Examination Survey 2008.
Metabolism. 2011 Oct; 60(10):1416-24.M

Abstract

We examined the association of serum ferritin levels with metabolic syndrome (MS) and diabetes mellitus in a representative sample of the adult South Korean population using data from the 2008 Korean National Health and Nutrition Examination Survey. We conducted a cross-sectional study of 6311 adults older than 20 years who participated in the 2008 Korean National Health and Nutrition Examination Survey. Metabolic syndrome was defined as the presence of at least 3 of the following: elevated blood pressure, low high-density lipoprotein cholesterol, elevated serum triglycerides, elevated plasma glucose, and abdominal obesity. Diabetes mellitus was defined as fasting glucose of at least 126 mg/dL. Insulin resistance was determined using the homeostasis model assessment estimate of insulin resistance. In a representative sample of the adult Korean population, MS was more prevalent in the highest quartile compared with the lowest quartile of serum ferritin concentrations in women following adjustments for age, education, smoking, alcohol intake, body mass index, aspartate aminotransferase, and alanine aminotransferase. Diabetes mellitus was more prevalent in the highest quartile compared with the lowest quartile of serum ferritin concentrations in premenopausal women and men. The geometric means of fasting insulin and insulin resistance determined using the homeostasis model assessment of insulin resistance in the fourth serum ferritin quartiles of postmenopausal women and men were significantly higher compared with those in the first quartile of the respective groups. The present study demonstrates that elevated serum ferritin concentrations are associated with an increased risk of MS and diabetes mellitus in a representative sample of the adult South Korean population.

Authors+Show Affiliations

Institute of Environmental & Occupational Medicine, Soonchunhyang University 646 Eupnae-ri, Shinchang-myun, Asan-si, Choongnam 336-745, South Korea.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21489582

Citation

Lee, Byung-Kook, et al. "Association of Serum Ferritin With Metabolic Syndrome and Diabetes Mellitus in the South Korean General Population According to the Korean National Health and Nutrition Examination Survey 2008." Metabolism: Clinical and Experimental, vol. 60, no. 10, 2011, pp. 1416-24.
Lee BK, Kim Y, Kim YI. Association of serum ferritin with metabolic syndrome and diabetes mellitus in the South Korean general population according to the Korean National Health and Nutrition Examination Survey 2008. Metabolism. 2011;60(10):1416-24.
Lee, B. K., Kim, Y., & Kim, Y. I. (2011). Association of serum ferritin with metabolic syndrome and diabetes mellitus in the South Korean general population according to the Korean National Health and Nutrition Examination Survey 2008. Metabolism: Clinical and Experimental, 60(10), 1416-24. https://doi.org/10.1016/j.metabol.2011.02.008
Lee BK, Kim Y, Kim YI. Association of Serum Ferritin With Metabolic Syndrome and Diabetes Mellitus in the South Korean General Population According to the Korean National Health and Nutrition Examination Survey 2008. Metabolism. 2011;60(10):1416-24. PubMed PMID: 21489582.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association of serum ferritin with metabolic syndrome and diabetes mellitus in the South Korean general population according to the Korean National Health and Nutrition Examination Survey 2008. AU - Lee,Byung-Kook, AU - Kim,Yangho, AU - Kim,Young-Il, Y1 - 2011/04/12/ PY - 2010/11/10/received PY - 2011/02/14/revised PY - 2011/02/15/accepted PY - 2011/4/15/entrez PY - 2011/4/15/pubmed PY - 2011/12/13/medline SP - 1416 EP - 24 JF - Metabolism: clinical and experimental JO - Metabolism VL - 60 IS - 10 N2 - We examined the association of serum ferritin levels with metabolic syndrome (MS) and diabetes mellitus in a representative sample of the adult South Korean population using data from the 2008 Korean National Health and Nutrition Examination Survey. We conducted a cross-sectional study of 6311 adults older than 20 years who participated in the 2008 Korean National Health and Nutrition Examination Survey. Metabolic syndrome was defined as the presence of at least 3 of the following: elevated blood pressure, low high-density lipoprotein cholesterol, elevated serum triglycerides, elevated plasma glucose, and abdominal obesity. Diabetes mellitus was defined as fasting glucose of at least 126 mg/dL. Insulin resistance was determined using the homeostasis model assessment estimate of insulin resistance. In a representative sample of the adult Korean population, MS was more prevalent in the highest quartile compared with the lowest quartile of serum ferritin concentrations in women following adjustments for age, education, smoking, alcohol intake, body mass index, aspartate aminotransferase, and alanine aminotransferase. Diabetes mellitus was more prevalent in the highest quartile compared with the lowest quartile of serum ferritin concentrations in premenopausal women and men. The geometric means of fasting insulin and insulin resistance determined using the homeostasis model assessment of insulin resistance in the fourth serum ferritin quartiles of postmenopausal women and men were significantly higher compared with those in the first quartile of the respective groups. The present study demonstrates that elevated serum ferritin concentrations are associated with an increased risk of MS and diabetes mellitus in a representative sample of the adult South Korean population. SN - 1532-8600 UR - https://www.unboundmedicine.com/medline/citation/21489582/Association_of_serum_ferritin_with_metabolic_syndrome_and_diabetes_mellitus_in_the_South_Korean_general_population_according_to_the_Korean_National_Health_and_Nutrition_Examination_Survey_2008_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0026-0495(11)00046-1 DB - PRIME DP - Unbound Medicine ER -