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Spine-shortening osteotomy for patients with tethered cord syndrome caused by lipomyelomeningocele.
J Neurosurg Spine. 2011 Jul; 15(1):21-7.JN

Abstract

OBJECTIVE

Tethered cord syndrome (TCS) is a disorder involving an abnormal stretching of the tethered spinal cord caused by several pathological conditions and presents with a variety of neurological symptoms. Untethering (tethered cord release) is the gold standard treatment for TCS. However, untethering carries risks of spinal cord injury and postoperative retethering. To avoid these potential risks, the authors applied spine-shortening osteotomy to adult patients with TCS, and report on the surgical procedure and treatment outcomes.

METHODS

Eight patients with TCS caused by a lipomyelomeningocele were surgically treated by the authors' original procedure of spine-shortening osteotomy. Six patients were male and 2 were females; average age at the time of surgery was 31 years old. Spine-shortening osteotomy was performed at the level of L-1 in all but 2 patients, in whom it was performed at T-12, with spinal fusion between T-12 and L-2 or T-11 and L-1 using a pedicle screw-rod system. The average follow-up period was 6.2 years and the patients' pre- and postoperative conditions were evaluated clinically and radiologically.

RESULTS

Preoperatively, all patients displayed severe neurological deficits such as motor disturbance, muscle atrophy, and bladder dysfunction. Several months before surgery, all showed progressive symptoms. Those symptoms showed initial improvement in 6 patients and stabilized in 2 postoperatively, but the improved symptoms worsened again in 4 of the 6 patients. The osteotomized vertebrae were shortened by 21 mm on average, and all spines showed complete bone union without loss of correction. At the final follow-up evaluations, 6 patients showed stabilization as per the modified Japanese Orthopaedic Association score for thoracic myelopathy.

CONCLUSIONS

Spine-shortening osteotomy successfully helps reduce the spinal cord tension without causing direct neural damage. At minimum, it stabilized the patients' symptoms and/or helped delay neurological deterioration for a period of time. Spine-shortening osteotomy might be a feasible mode of treatment for adult TCS caused by a spinal lipoma.

Authors+Show Affiliations

Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21495816

Citation

Kokubun, Shoichi, et al. "Spine-shortening Osteotomy for Patients With Tethered Cord Syndrome Caused By Lipomyelomeningocele." Journal of Neurosurgery. Spine, vol. 15, no. 1, 2011, pp. 21-7.
Kokubun S, Ozawa H, Aizawa T, et al. Spine-shortening osteotomy for patients with tethered cord syndrome caused by lipomyelomeningocele. J Neurosurg Spine. 2011;15(1):21-7.
Kokubun, S., Ozawa, H., Aizawa, T., Ly, N. M., & Tanaka, Y. (2011). Spine-shortening osteotomy for patients with tethered cord syndrome caused by lipomyelomeningocele. Journal of Neurosurgery. Spine, 15(1), 21-7. https://doi.org/10.3171/2011.2.SPINE10114
Kokubun S, et al. Spine-shortening Osteotomy for Patients With Tethered Cord Syndrome Caused By Lipomyelomeningocele. J Neurosurg Spine. 2011;15(1):21-7. PubMed PMID: 21495816.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spine-shortening osteotomy for patients with tethered cord syndrome caused by lipomyelomeningocele. AU - Kokubun,Shoichi, AU - Ozawa,Hiroshi, AU - Aizawa,Toshimi, AU - Ly,Ngo Minh, AU - Tanaka,Yasuhisa, Y1 - 2011/04/15/ PY - 2011/4/19/entrez PY - 2011/4/19/pubmed PY - 2011/9/14/medline SP - 21 EP - 7 JF - Journal of neurosurgery. Spine JO - J Neurosurg Spine VL - 15 IS - 1 N2 - OBJECTIVE: Tethered cord syndrome (TCS) is a disorder involving an abnormal stretching of the tethered spinal cord caused by several pathological conditions and presents with a variety of neurological symptoms. Untethering (tethered cord release) is the gold standard treatment for TCS. However, untethering carries risks of spinal cord injury and postoperative retethering. To avoid these potential risks, the authors applied spine-shortening osteotomy to adult patients with TCS, and report on the surgical procedure and treatment outcomes. METHODS: Eight patients with TCS caused by a lipomyelomeningocele were surgically treated by the authors' original procedure of spine-shortening osteotomy. Six patients were male and 2 were females; average age at the time of surgery was 31 years old. Spine-shortening osteotomy was performed at the level of L-1 in all but 2 patients, in whom it was performed at T-12, with spinal fusion between T-12 and L-2 or T-11 and L-1 using a pedicle screw-rod system. The average follow-up period was 6.2 years and the patients' pre- and postoperative conditions were evaluated clinically and radiologically. RESULTS: Preoperatively, all patients displayed severe neurological deficits such as motor disturbance, muscle atrophy, and bladder dysfunction. Several months before surgery, all showed progressive symptoms. Those symptoms showed initial improvement in 6 patients and stabilized in 2 postoperatively, but the improved symptoms worsened again in 4 of the 6 patients. The osteotomized vertebrae were shortened by 21 mm on average, and all spines showed complete bone union without loss of correction. At the final follow-up evaluations, 6 patients showed stabilization as per the modified Japanese Orthopaedic Association score for thoracic myelopathy. CONCLUSIONS: Spine-shortening osteotomy successfully helps reduce the spinal cord tension without causing direct neural damage. At minimum, it stabilized the patients' symptoms and/or helped delay neurological deterioration for a period of time. Spine-shortening osteotomy might be a feasible mode of treatment for adult TCS caused by a spinal lipoma. SN - 1547-5646 UR - https://www.unboundmedicine.com/medline/citation/21495816/Spine_shortening_osteotomy_for_patients_with_tethered_cord_syndrome_caused_by_lipomyelomeningocele_ DB - PRIME DP - Unbound Medicine ER -