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An examination of the structure of posttraumatic stress disorder in relation to the anxiety and depressive disorders.
J Affect Disord 2011; 132(1-2):165-72JA

Abstract

The nature and structure of posttraumatic stress disorder (PTSD) has been the subject of much interest in recent times. This research has been represented by two streams, the first representing a substantive body of work which focuses specifically on the factor structure of PTSD and the second exploring PTSD's relationship with other mood and anxiety disorders. The present study attempted to bring these two streams together by examining structural models of PTSD and their relationship with dimensions underlying other mood and anxiety disorders. PTSD, anxiety and mood disorder data from 989 injury survivors interviewed 3-months following their injury were analyzed using a series of confirmatory factor analyses (CFA) to identify the optimal structural model. CFA analyses indicated that the best fitting model included PTSD's re-experiencing (B1-5), active avoidance (C1-2), and hypervigilance and startle (D4-5) loading onto a Fear factor (represented by panic disorder, agoraphobia and social phobia) and the PTSD dysphoria symptoms (numbing symptoms C3-7 and hyperarousal symptoms D1-3) loading onto an Anxious Misery/Distress factor (represented by depression, generalized anxiety disorder and obsessive compulsive disorder). The findings have implications for informing potential revisions to the structure of the diagnosis of PTSD and the diagnostic algorithm to be applied, with the aim of enhancing diagnostic specificity.

Authors+Show Affiliations

Australian Centre for Posttraumatic Mental Health and Department of Psychiatry, University of Melbourne, Victoria, Australia. dforbes@unimelb.edu.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21496930

Citation

Forbes, David, et al. "An Examination of the Structure of Posttraumatic Stress Disorder in Relation to the Anxiety and Depressive Disorders." Journal of Affective Disorders, vol. 132, no. 1-2, 2011, pp. 165-72.
Forbes D, Lockwood E, Elhai JD, et al. An examination of the structure of posttraumatic stress disorder in relation to the anxiety and depressive disorders. J Affect Disord. 2011;132(1-2):165-72.
Forbes, D., Lockwood, E., Elhai, J. D., Creamer, M., O'Donnell, M., Bryant, R., ... Silove, D. (2011). An examination of the structure of posttraumatic stress disorder in relation to the anxiety and depressive disorders. Journal of Affective Disorders, 132(1-2), pp. 165-72. doi:10.1016/j.jad.2011.02.011.
Forbes D, et al. An Examination of the Structure of Posttraumatic Stress Disorder in Relation to the Anxiety and Depressive Disorders. J Affect Disord. 2011;132(1-2):165-72. PubMed PMID: 21496930.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An examination of the structure of posttraumatic stress disorder in relation to the anxiety and depressive disorders. AU - Forbes,David, AU - Lockwood,Emma, AU - Elhai,Jon D, AU - Creamer,Mark, AU - O'Donnell,Meaghan, AU - Bryant,Richard, AU - McFarlane,Alexander, AU - Silove,Derrick, Y1 - 2011/04/14/ PY - 2011/01/18/received PY - 2011/02/11/revised PY - 2011/02/14/accepted PY - 2011/4/19/entrez PY - 2011/4/19/pubmed PY - 2011/11/2/medline SP - 165 EP - 72 JF - Journal of affective disorders JO - J Affect Disord VL - 132 IS - 1-2 N2 - The nature and structure of posttraumatic stress disorder (PTSD) has been the subject of much interest in recent times. This research has been represented by two streams, the first representing a substantive body of work which focuses specifically on the factor structure of PTSD and the second exploring PTSD's relationship with other mood and anxiety disorders. The present study attempted to bring these two streams together by examining structural models of PTSD and their relationship with dimensions underlying other mood and anxiety disorders. PTSD, anxiety and mood disorder data from 989 injury survivors interviewed 3-months following their injury were analyzed using a series of confirmatory factor analyses (CFA) to identify the optimal structural model. CFA analyses indicated that the best fitting model included PTSD's re-experiencing (B1-5), active avoidance (C1-2), and hypervigilance and startle (D4-5) loading onto a Fear factor (represented by panic disorder, agoraphobia and social phobia) and the PTSD dysphoria symptoms (numbing symptoms C3-7 and hyperarousal symptoms D1-3) loading onto an Anxious Misery/Distress factor (represented by depression, generalized anxiety disorder and obsessive compulsive disorder). The findings have implications for informing potential revisions to the structure of the diagnosis of PTSD and the diagnostic algorithm to be applied, with the aim of enhancing diagnostic specificity. SN - 1573-2517 UR - https://www.unboundmedicine.com/medline/citation/21496930/An_examination_of_the_structure_of_posttraumatic_stress_disorder_in_relation_to_the_anxiety_and_depressive_disorders_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-0327(11)00065-6 DB - PRIME DP - Unbound Medicine ER -