Tags

Type your tag names separated by a space and hit enter

Sex differences in the relationship between metabolic syndrome and pulmonary function: the 2007 Korean National Health and Nutrition Examination Survey.

Abstract

Pulmonary function impairment has a connection with abdominal obesity, type 2 diabetes, and insulin resistance. Sex differences in lifestyle factors, and pulmonary structure and function may affect pulmonary function in different manners. This study focused on sex differences in the relationship of MetS and its component with pulmonary function. Among 2,614 Korean adults (1,059 men; 1,555 women), pulmonary function was measured by the percentage of predicted forced vital capacity (FVC (%)) and a ratio between forced expiratory volume in 1 second (FEV(1))/FVC. FVC (%) and FEV(1)/FVC were compared according to the presence of MetS and its components. Multiple linear regression analysis was conducted to assess the association between FVC (%), FEV(1)/FVC and clinical variables. We found sex differences in the relationship of MetS and its components with pulmonary function. FVC (%) was significantly lower in subjects with MetS than in those without MetS in both men and women, and FEV(1)/FVC was lower in subjects with MetS only in women. Among components of MetS, waist circumference, blood pressure and fasting plasma glucose, and HDL-cholesterol were independently related to FVC (%) in men, whereas waist circumference was significantly associated with FVC (%) in women. Blood pressure was found to be an independent factor of FEV(1)/FVC in men, whereas blood pressure, fasting plasma glucose and HDL-cholesterol independently determined FEV(1)/FVC in women. These findings suggest that sex-specific association between MetS and lung function measures should be considered in clinical practice.

Links

  • FREE Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Family Medicine, Yonsei University College of Medicine, 250 Sungsan-ro, Seodaemun-gu, Seoul 120-752, Korea.

    , , ,

    Source

    Endocrine journal 58:6 2011 pg 459-65

    MeSH

    Adult
    Aged
    Asian Continental Ancestry Group
    Blood Glucose
    Blood Pressure
    Cholesterol, HDL
    Cross-Sectional Studies
    Female
    Forced Expiratory Volume
    Humans
    Lung
    Male
    Metabolic Syndrome
    Middle Aged
    Nutrition Surveys
    Republic of Korea
    Sex Characteristics
    Vital Capacity
    Waist Circumference

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    21502707

    Citation

    Choi, Ji-Ho, et al. "Sex Differences in the Relationship Between Metabolic Syndrome and Pulmonary Function: the 2007 Korean National Health and Nutrition Examination Survey." Endocrine Journal, vol. 58, no. 6, 2011, pp. 459-65.
    Choi JH, Park S, Shin YH, et al. Sex differences in the relationship between metabolic syndrome and pulmonary function: the 2007 Korean National Health and Nutrition Examination Survey. Endocr J. 2011;58(6):459-65.
    Choi, J. H., Park, S., Shin, Y. H., Kim, M. Y., & Lee, Y. J. (2011). Sex differences in the relationship between metabolic syndrome and pulmonary function: the 2007 Korean National Health and Nutrition Examination Survey. Endocrine Journal, 58(6), pp. 459-65.
    Choi JH, et al. Sex Differences in the Relationship Between Metabolic Syndrome and Pulmonary Function: the 2007 Korean National Health and Nutrition Examination Survey. Endocr J. 2011;58(6):459-65. PubMed PMID: 21502707.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Sex differences in the relationship between metabolic syndrome and pulmonary function: the 2007 Korean National Health and Nutrition Examination Survey. AU - Choi,Ji-Ho, AU - Park,Sunghoon, AU - Shin,Youn-Ho, AU - Kim,Moo-Young, AU - Lee,Yong-Jae, Y1 - 2011/04/19/ PY - 2011/4/20/entrez PY - 2011/4/20/pubmed PY - 2011/11/1/medline SP - 459 EP - 65 JF - Endocrine journal JO - Endocr. J. VL - 58 IS - 6 N2 - Pulmonary function impairment has a connection with abdominal obesity, type 2 diabetes, and insulin resistance. Sex differences in lifestyle factors, and pulmonary structure and function may affect pulmonary function in different manners. This study focused on sex differences in the relationship of MetS and its component with pulmonary function. Among 2,614 Korean adults (1,059 men; 1,555 women), pulmonary function was measured by the percentage of predicted forced vital capacity (FVC (%)) and a ratio between forced expiratory volume in 1 second (FEV(1))/FVC. FVC (%) and FEV(1)/FVC were compared according to the presence of MetS and its components. Multiple linear regression analysis was conducted to assess the association between FVC (%), FEV(1)/FVC and clinical variables. We found sex differences in the relationship of MetS and its components with pulmonary function. FVC (%) was significantly lower in subjects with MetS than in those without MetS in both men and women, and FEV(1)/FVC was lower in subjects with MetS only in women. Among components of MetS, waist circumference, blood pressure and fasting plasma glucose, and HDL-cholesterol were independently related to FVC (%) in men, whereas waist circumference was significantly associated with FVC (%) in women. Blood pressure was found to be an independent factor of FEV(1)/FVC in men, whereas blood pressure, fasting plasma glucose and HDL-cholesterol independently determined FEV(1)/FVC in women. These findings suggest that sex-specific association between MetS and lung function measures should be considered in clinical practice. SN - 1348-4540 UR - https://www.unboundmedicine.com/medline/citation/21502707/Sex_differences_in_the_relationship_between_metabolic_syndrome_and_pulmonary_function:_the_2007_Korean_National_Health_and_Nutrition_Examination_Survey_ L2 - http://joi.jlc.jst.go.jp/JST.JSTAGE/endocrj/K11E-011?from=PubMed DB - PRIME DP - Unbound Medicine ER -