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[Surgical treatment of chronic pancreatitis, 2010].
Magy Seb. 2011 Apr; 64(2):63-8.MS

Abstract

INTRODUCTION

Chronic pancreatitis (CP) is a benign inflammatory process, which can cause enlargement of the pancreatic head accompanied by severe pain and weight loss, and often leads to a significant reduction in quality of life (QoL). Basically, the disease is characterised by pain and functional disorders which are initially treated with conservative therapy, but in case of complications (uncontrollable pain or obstruction) surgical treatment is required.

METHODS

This article reviews the relevant literature of CP treatment, in particular randomized controlled trials and meta-analyses were involved with a comparison of different surgical treatment options for the management of CP complications.

RESULTS

Recent studies have demonstrated that surgical procedures are superior to endoscopic therapy as regards long-term results of QoL and pain control. There was no significant difference found in postoperative pain relief and overall mortality when duodenum-preserving pancreatic head resection (DPPHR) of Beger and its modification (duodenum and organ-preserving pancreatic head resection [DOPPHR]) were compared with pancreatoduodenectomy (PD), but hospital stay, weight gain, exocrine and endocrine insufficiency, and QoL were significantly better in the DPPHR and DOPPHR groups.

CONCLUSION

DPPHR and PD seem to be equally effective in terms of postoperative pain relief and overall mortality. However, recent data suggest that DOPPHR is superior in the treatment of CP with regard to several peri- and postoperative outcome parameters and QoL. Therefore, this should be the preferable treatment option for CP complications.

Authors+Show Affiliations

Szegedi Tudományegyetem, Általános Orvostudományi Kar, Sebészeti Klinika, Szeged. fg@surg.szote.u-uzeged.hu

Pub Type(s)

English Abstract
Journal Article
Review

Language

hun

PubMed ID

21504854

Citation

Farkas, Gyula. "[Surgical Treatment of Chronic Pancreatitis, 2010]." Magyar Sebeszet, vol. 64, no. 2, 2011, pp. 63-8.
Farkas G. [Surgical treatment of chronic pancreatitis, 2010]. Magy Seb. 2011;64(2):63-8.
Farkas, G. (2011). [Surgical treatment of chronic pancreatitis, 2010]. Magyar Sebeszet, 64(2), 63-8. https://doi.org/10.1556/MaSeb.64.2011.2.2
Farkas G. [Surgical Treatment of Chronic Pancreatitis, 2010]. Magy Seb. 2011;64(2):63-8. PubMed PMID: 21504854.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Surgical treatment of chronic pancreatitis, 2010]. A1 - Farkas,Gyula, PY - 2011/4/21/entrez PY - 2011/4/21/pubmed PY - 2011/6/4/medline SP - 63 EP - 8 JF - Magyar sebeszet JO - Magy Seb VL - 64 IS - 2 N2 - INTRODUCTION: Chronic pancreatitis (CP) is a benign inflammatory process, which can cause enlargement of the pancreatic head accompanied by severe pain and weight loss, and often leads to a significant reduction in quality of life (QoL). Basically, the disease is characterised by pain and functional disorders which are initially treated with conservative therapy, but in case of complications (uncontrollable pain or obstruction) surgical treatment is required. METHODS: This article reviews the relevant literature of CP treatment, in particular randomized controlled trials and meta-analyses were involved with a comparison of different surgical treatment options for the management of CP complications. RESULTS: Recent studies have demonstrated that surgical procedures are superior to endoscopic therapy as regards long-term results of QoL and pain control. There was no significant difference found in postoperative pain relief and overall mortality when duodenum-preserving pancreatic head resection (DPPHR) of Beger and its modification (duodenum and organ-preserving pancreatic head resection [DOPPHR]) were compared with pancreatoduodenectomy (PD), but hospital stay, weight gain, exocrine and endocrine insufficiency, and QoL were significantly better in the DPPHR and DOPPHR groups. CONCLUSION: DPPHR and PD seem to be equally effective in terms of postoperative pain relief and overall mortality. However, recent data suggest that DOPPHR is superior in the treatment of CP with regard to several peri- and postoperative outcome parameters and QoL. Therefore, this should be the preferable treatment option for CP complications. SN - 0025-0295 UR - https://www.unboundmedicine.com/medline/citation/21504854/[Surgical_treatment_of_chronic_pancreatitis_2010]_ L2 - http://www.akademiai.com/doi/full/10.1556/MaSeb.64.2011.2.2?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -