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Long-term experience with a low-dose oral contraceptive.
Gynecol Endocrinol. 1990 Dec; 4(4):277-86.GE

Abstract

Oral contraception has proved to be the most efficient reversible method of fertility control for over 25 years. During this period, various investigations and epidemiological studies have suggested that some risks may be involved, but, on the other hand, a number of non-contraceptive benefits have become obvious. The results of these investigations were taken into account when new formulations had to be developed, with an aim to improving hormonal fertility control with regard to its tolerance, cycle control, and impact on metabolism. Since then, the objective of research has been to contrive new hormonal contraceptives which ensure safety to the largest possible extent, from a medical point of view, for the sake of the patient, without affecting contraceptive effectiveness. The aim to reduce side-effects connected with the use of oral contraception, as well as to lower the risks possibly involved, has obviously been achieved by extensive research. Both by devising a new substance and reducing doses, the criteria of modern low-dose oral contraception have been met, as has become evident in the course of the clinical experience gathered with Femovan.

Authors+Show Affiliations

Schering AG, Medical Dept. Germany, Berlin.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study

Language

eng

PubMed ID

2150581

Citation

Brill, K, et al. "Long-term Experience With a Low-dose Oral Contraceptive." Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, vol. 4, no. 4, 1990, pp. 277-86.
Brill K, Schnitker J, Albring M. Long-term experience with a low-dose oral contraceptive. Gynecol Endocrinol. 1990;4(4):277-86.
Brill, K., Schnitker, J., & Albring, M. (1990). Long-term experience with a low-dose oral contraceptive. Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, 4(4), 277-86.
Brill K, Schnitker J, Albring M. Long-term Experience With a Low-dose Oral Contraceptive. Gynecol Endocrinol. 1990;4(4):277-86. PubMed PMID: 2150581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term experience with a low-dose oral contraceptive. AU - Brill,K, AU - Schnitker,J, AU - Albring,M, PY - 1990/12/1/pubmed PY - 1990/12/1/medline PY - 1990/12/1/entrez KW - Acne KW - Biology KW - Bleeding KW - Blood Pressure KW - Body Weight KW - Clinical Research KW - Contraception KW - Contraception Continuation KW - Contraception Failure KW - Contraceptive Agents KW - Contraceptive Agents, Estrogen KW - Contraceptive Agents, Female KW - Contraceptive Agents, Progestin KW - Contraceptive Effectiveness KW - Contraceptive Methods KW - Contraceptive Usage KW - Dermatitis KW - Developed Countries KW - Diseases KW - Ethinyl Estradiol KW - Europe KW - Family Planning KW - Germany KW - Gestodene KW - Headache KW - Hemic System KW - Human Volunteers KW - Menorrhagia KW - Menstruation Disorders KW - Metrorrhagia KW - Nausea KW - Nervousness KW - Oral Contraceptives KW - Oral Contraceptives, Combined KW - Pearl's Formula KW - Physiology KW - Research Methodology KW - Research Report KW - Signs And Symptoms KW - Use-effectiveness KW - Vertigo KW - Western Europe SP - 277 EP - 86 JF - Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology JO - Gynecol Endocrinol VL - 4 IS - 4 N2 - Oral contraception has proved to be the most efficient reversible method of fertility control for over 25 years. During this period, various investigations and epidemiological studies have suggested that some risks may be involved, but, on the other hand, a number of non-contraceptive benefits have become obvious. The results of these investigations were taken into account when new formulations had to be developed, with an aim to improving hormonal fertility control with regard to its tolerance, cycle control, and impact on metabolism. Since then, the objective of research has been to contrive new hormonal contraceptives which ensure safety to the largest possible extent, from a medical point of view, for the sake of the patient, without affecting contraceptive effectiveness. The aim to reduce side-effects connected with the use of oral contraception, as well as to lower the risks possibly involved, has obviously been achieved by extensive research. Both by devising a new substance and reducing doses, the criteria of modern low-dose oral contraception have been met, as has become evident in the course of the clinical experience gathered with Femovan. SN - 0951-3590 UR - https://www.unboundmedicine.com/medline/citation/2150581/Long_term_experience_with_a_low_dose_oral_contraceptive_ L2 - https://www.tandfonline.com/doi/full/10.3109/09513599009024982 DB - PRIME DP - Unbound Medicine ER -