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The blue man: a novel cutaneous manifestation of systemic amyloidosis.
Amyloid. 2011 Sep; 18(3):156-9.A

Abstract

Multiple cutaneous manifestations of amyloidosis have been described, and include periorbital purpura, plaques, nodules, and papules. Blue skin tint is not a previously described feature of cutaneous amyloidosis. We report the clinical case of a patient with known multiple myeloma and amyloidosis of the gastrointestinal tract who presented with progressive "blueness" of the skin. Dermatopathological examination and mass spectrometry of a skin biopsy specimen revealed the presence of subcutaneous amyloid light chain (AL) deposition. We believe this to be the first reported case of blue skin resulting from systemic amyloidosis.

Authors+Show Affiliations

Division of Internal Medicine, Mayo Clinic Arizona, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA. campbell.mark@mayo.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21506660

Citation

Campbell, Mark, et al. "The Blue Man: a Novel Cutaneous Manifestation of Systemic Amyloidosis." Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis, vol. 18, no. 3, 2011, pp. 156-9.
Campbell M, Rosenthal A, Kundranda M, et al. The blue man: a novel cutaneous manifestation of systemic amyloidosis. Amyloid. 2011;18(3):156-9.
Campbell, M., Rosenthal, A., Kundranda, M., Pickert, A., Dicaudo, D., Dogan, A., & Mikhael, J. (2011). The blue man: a novel cutaneous manifestation of systemic amyloidosis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis, 18(3), 156-9. https://doi.org/10.3109/13506129.2011.571318
Campbell M, et al. The Blue Man: a Novel Cutaneous Manifestation of Systemic Amyloidosis. Amyloid. 2011;18(3):156-9. PubMed PMID: 21506660.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The blue man: a novel cutaneous manifestation of systemic amyloidosis. AU - Campbell,Mark, AU - Rosenthal,Allison, AU - Kundranda,Madappa, AU - Pickert,Amanda, AU - Dicaudo,David, AU - Dogan,Ahmet, AU - Mikhael,Joseph, Y1 - 2011/04/20/ PY - 2011/4/22/entrez PY - 2011/4/22/pubmed PY - 2012/1/14/medline SP - 156 EP - 9 JF - Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis JO - Amyloid VL - 18 IS - 3 N2 - Multiple cutaneous manifestations of amyloidosis have been described, and include periorbital purpura, plaques, nodules, and papules. Blue skin tint is not a previously described feature of cutaneous amyloidosis. We report the clinical case of a patient with known multiple myeloma and amyloidosis of the gastrointestinal tract who presented with progressive "blueness" of the skin. Dermatopathological examination and mass spectrometry of a skin biopsy specimen revealed the presence of subcutaneous amyloid light chain (AL) deposition. We believe this to be the first reported case of blue skin resulting from systemic amyloidosis. SN - 1744-2818 UR - https://www.unboundmedicine.com/medline/citation/21506660/The_blue_man:_a_novel_cutaneous_manifestation_of_systemic_amyloidosis_ L2 - http://www.tandfonline.com/doi/full/10.3109/13506129.2011.571318 DB - PRIME DP - Unbound Medicine ER -