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[Q fever as a cause of acute hepatitis accompanying fever].
Korean J Gastroenterol. 2011 Mar; 57(3):189-93.KJ

Abstract

Q fever is a zoonotic infection caused by Coxiella burnetti, which has been previously regarded as an uncommon infectious disease in Korea but is sporadically reported recently. Common manifestations of acute Q fever usually present as influenza-like illness, pneumonia and occasionally hepatitis. Herein, we report 4 cases of acute Q fever as a cause of acute hepatitis and fever. All patients had fever and non-specific symptoms, and laboratory test showed acute hepatitis. Antibody surveys for many virus infections and bacterial cultures were negative. Finally, they were diagnosed acute Q fever by an indirect microimmunofluorescence test. Liver biopsy in 3 patients revealed granuloma including one with typical fibrin-ring. All patients had complete resolution of symptoms and signs with doxycycline treatment. Q fever should be considered in the differential diagnosis of patients with fever of unknown origin with acute hepatitis in Korea.

Authors+Show Affiliations

Departments of Internal Medicine, Korea University of Medical College, Seoul, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

kor

PubMed ID

21519168

Citation

Lee, Hyun Jung, et al. "[Q Fever as a Cause of Acute Hepatitis Accompanying Fever]." The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi, vol. 57, no. 3, 2011, pp. 189-93.
Lee HJ, Kim JH, Yoon EL, et al. [Q fever as a cause of acute hepatitis accompanying fever]. Korean J Gastroenterol. 2011;57(3):189-93.
Lee, H. J., Kim, J. H., Yoon, E. L., Lee, Y. S., Yeon, J. E., Byun, K. S., Kim, B. H., & Ryu, Y. (2011). [Q fever as a cause of acute hepatitis accompanying fever]. The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi, 57(3), 189-93. https://doi.org/10.4166/2011.57.3.189
Lee HJ, et al. [Q Fever as a Cause of Acute Hepatitis Accompanying Fever]. Korean J Gastroenterol. 2011;57(3):189-93. PubMed PMID: 21519168.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Q fever as a cause of acute hepatitis accompanying fever]. AU - Lee,Hyun Jung, AU - Kim,Ji Hoon, AU - Yoon,Eileen L, AU - Lee,Young Sun, AU - Yeon,Jong Eun, AU - Byun,Kwan Soo, AU - Kim,Baek-Hui, AU - Ryu,Youngjoon, PY - 2011/4/27/entrez PY - 2011/4/27/pubmed PY - 2011/8/17/medline SP - 189 EP - 93 JF - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi JO - Korean J Gastroenterol VL - 57 IS - 3 N2 - Q fever is a zoonotic infection caused by Coxiella burnetti, which has been previously regarded as an uncommon infectious disease in Korea but is sporadically reported recently. Common manifestations of acute Q fever usually present as influenza-like illness, pneumonia and occasionally hepatitis. Herein, we report 4 cases of acute Q fever as a cause of acute hepatitis and fever. All patients had fever and non-specific symptoms, and laboratory test showed acute hepatitis. Antibody surveys for many virus infections and bacterial cultures were negative. Finally, they were diagnosed acute Q fever by an indirect microimmunofluorescence test. Liver biopsy in 3 patients revealed granuloma including one with typical fibrin-ring. All patients had complete resolution of symptoms and signs with doxycycline treatment. Q fever should be considered in the differential diagnosis of patients with fever of unknown origin with acute hepatitis in Korea. SN - 2233-6869 UR - https://www.unboundmedicine.com/medline/citation/21519168/[Q_fever_as_a_cause_of_acute_hepatitis_accompanying_fever]_ DB - PRIME DP - Unbound Medicine ER -