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Severe Mycoplasma pneumoniae-associated mucositis treated with immunoglobulins.
Acta Paediatr. 2011 Nov; 100(11):e238-40.AP

Abstract

Mycoplasma pneumoniae-associated mucositis (MPAM), previously labelled as atypical Stevens-Johnson syndrome (SJS), SJS with minimal or no skin manifestations, is a rare non-respiratory manifestation of Mycoplasma pneumoniae infection. The nineteen cases described so far in children and young adults were characterized by a high male gender prevalence (16/19) and a good response to appropriate antibiotic treatment and supportive care in the majority of patients. We describe a case of MPAM in a previously healthy girl, who improved after a 0.5 g/kg daily dose of intravenous immunoglobulins (IVIG) for four consecutive days, after traditional therapy had failed.

CONCLUSION

The successful treatment with IVIG described in this report suggests that, where appropriate antibiotic and supportive therapy fails to improve the clinical course of severe MPAM, IVIG treatment is worth considering.

Authors+Show Affiliations

Department of Pediatrics, University of Padova, Italy. silvia.bressan.1@unipd.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21535132

Citation

Bressan, Silvia, et al. "Severe Mycoplasma Pneumoniae-associated Mucositis Treated With Immunoglobulins." Acta Paediatrica (Oslo, Norway : 1992), vol. 100, no. 11, 2011, pp. e238-40.
Bressan S, Mion T, Andreola B, et al. Severe Mycoplasma pneumoniae-associated mucositis treated with immunoglobulins. Acta Paediatr. 2011;100(11):e238-40.
Bressan, S., Mion, T., Andreola, B., Bisogno, G., & Da Dalt, L. (2011). Severe Mycoplasma pneumoniae-associated mucositis treated with immunoglobulins. Acta Paediatrica (Oslo, Norway : 1992), 100(11), e238-40. https://doi.org/10.1111/j.1651-2227.2011.02342.x
Bressan S, et al. Severe Mycoplasma Pneumoniae-associated Mucositis Treated With Immunoglobulins. Acta Paediatr. 2011;100(11):e238-40. PubMed PMID: 21535132.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Severe Mycoplasma pneumoniae-associated mucositis treated with immunoglobulins. AU - Bressan,Silvia, AU - Mion,Teresa, AU - Andreola,Barbara, AU - Bisogno,Gianni, AU - Da Dalt,Liviana, Y1 - 2011/05/27/ PY - 2011/5/4/entrez PY - 2011/5/4/pubmed PY - 2012/2/14/medline SP - e238 EP - 40 JF - Acta paediatrica (Oslo, Norway : 1992) JO - Acta Paediatr. VL - 100 IS - 11 N2 - UNLABELLED: Mycoplasma pneumoniae-associated mucositis (MPAM), previously labelled as atypical Stevens-Johnson syndrome (SJS), SJS with minimal or no skin manifestations, is a rare non-respiratory manifestation of Mycoplasma pneumoniae infection. The nineteen cases described so far in children and young adults were characterized by a high male gender prevalence (16/19) and a good response to appropriate antibiotic treatment and supportive care in the majority of patients. We describe a case of MPAM in a previously healthy girl, who improved after a 0.5 g/kg daily dose of intravenous immunoglobulins (IVIG) for four consecutive days, after traditional therapy had failed. CONCLUSION: The successful treatment with IVIG described in this report suggests that, where appropriate antibiotic and supportive therapy fails to improve the clinical course of severe MPAM, IVIG treatment is worth considering. SN - 1651-2227 UR - https://www.unboundmedicine.com/medline/citation/21535132/Severe_Mycoplasma_pneumoniae_associated_mucositis_treated_with_immunoglobulins_ L2 - https://doi.org/10.1111/j.1651-2227.2011.02342.x DB - PRIME DP - Unbound Medicine ER -