Tags

Type your tag names separated by a space and hit enter

Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany.
Am J Ind Med. 2011 Jul; 54(7):510-4.AJ

Abstract

BACKGROUND

As several studies have identified asbestos exposure as an independent occupational risk factor for laryngeal cancer, the aim of our study was to confirm this association.

METHODS

In a population-based case-control study on laryngeal cancer in South-West Germany occupational exposures and other risk factors were obtained by face-to-face interviews using a detailed standardized questionnaire covering the complete individual working history, supplemented by job-specific questionnaires (JSQ) especially for selected jobs known to entail exposure to asbestos. Detailed exposure information was collected over a wide range of asbestos related jobs and branches and analyzed using different modeling strategies.

RESULTS

Seventy-three (28.4%) cases and 158 (20.5%) controls reported any exposure to asbestos. Elevated risk estimates for asbestos exposure were found. However, those became substantially reduced after adjustment for smoking and alcohol.

CONCLUSION

Moderately elevated risks for laryngeal cancer after exposure to asbestos were confirmed. Difficulties in the collection of adequate exposure data were demonstrated.

Authors+Show Affiliations

Institute of Public Health, University of Heidelberg, Germany. heribert.ramroth@uni-heidelberg.deNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21538446

Citation

Ramroth, Heribert, et al. "Occupational Asbestos Exposure as a Risk Factor for Laryngeal Carcinoma in a Population-based Case-control Study From Germany." American Journal of Industrial Medicine, vol. 54, no. 7, 2011, pp. 510-4.
Ramroth H, Ahrens W, Dietz A, et al. Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany. Am J Ind Med. 2011;54(7):510-4.
Ramroth, H., Ahrens, W., Dietz, A., & Becher, H. (2011). Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany. American Journal of Industrial Medicine, 54(7), 510-4. https://doi.org/10.1002/ajim.20963
Ramroth H, et al. Occupational Asbestos Exposure as a Risk Factor for Laryngeal Carcinoma in a Population-based Case-control Study From Germany. Am J Ind Med. 2011;54(7):510-4. PubMed PMID: 21538446.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany. AU - Ramroth,Heribert, AU - Ahrens,Wolfgang, AU - Dietz,Andreas, AU - Becher,Heiko, Y1 - 2011/05/02/ PY - 2011/04/06/accepted PY - 2011/5/4/entrez PY - 2011/5/4/pubmed PY - 2011/10/1/medline SP - 510 EP - 4 JF - American journal of industrial medicine JO - Am. J. Ind. Med. VL - 54 IS - 7 N2 - BACKGROUND: As several studies have identified asbestos exposure as an independent occupational risk factor for laryngeal cancer, the aim of our study was to confirm this association. METHODS: In a population-based case-control study on laryngeal cancer in South-West Germany occupational exposures and other risk factors were obtained by face-to-face interviews using a detailed standardized questionnaire covering the complete individual working history, supplemented by job-specific questionnaires (JSQ) especially for selected jobs known to entail exposure to asbestos. Detailed exposure information was collected over a wide range of asbestos related jobs and branches and analyzed using different modeling strategies. RESULTS: Seventy-three (28.4%) cases and 158 (20.5%) controls reported any exposure to asbestos. Elevated risk estimates for asbestos exposure were found. However, those became substantially reduced after adjustment for smoking and alcohol. CONCLUSION: Moderately elevated risks for laryngeal cancer after exposure to asbestos were confirmed. Difficulties in the collection of adequate exposure data were demonstrated. SN - 1097-0274 UR - https://www.unboundmedicine.com/medline/citation/21538446/Occupational_asbestos_exposure_as_a_risk_factor_for_laryngeal_carcinoma_in_a_population_based_case_control_study_from_Germany_ L2 - https://doi.org/10.1002/ajim.20963 DB - PRIME DP - Unbound Medicine ER -