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The molecular clock in terms of quantum information processing of coherent states, entanglement and replication of evolutionarily selected decohered isomers.
Interdiscip Sci. 2011 Jun; 3(2):91-109.IS

Abstract

Evolutionary pressures have selected quantum uncertainty limits -ΔxΔp (x) ≥ 1/2ħ-to operate on metastable amino DNA protons. This introduces a probability of molecular clock arrangement, keto-amino → enol-imine, where product protons are entangled and participate in coupled quantum oscillation at frequencies of ∼ 10(13) s(-1). The ket "seen by" the transcriptase, reading a coherent enol-imine G'-state, is |φ >= α| + + > +β|+- > +γ|-+ > +δ|-->. The transcriptase implements its measurement and generates an output qubit of observable genetic specificity information in an interval Δt ≪ 10(-13) s. These quantum measurements can specify the relative distribution of coherent G'-C' states at time of measurement. The ensuing quantum entanglement between coherent protons and transcriptase units is utilized as a resource to generate proper decoherence and introduce selected time-dependent substitutions, ts, and deletions, td. Topal-Fresco ts are G'202 → T, G'002 → C, *G020(0) → A and *C202(2) → T, whereas td are exhibited at coherent *A-*T sites. Variation in clock 'tic-rate' is a consequence of clock introduction of initiation codons - UUG, CUG, AUG, GUG - and stop codons, UAA, UAG, UGA. Using approximate quantum methods for times t < ∼ 100 y, the probability, P(t), of keto-amino → enolimine arrangement is P (ρ)(t) = 1/2(γ (ρ)/ħ)(2) t (2) where γ (ρ) is the energy shift. This introduces a quantum Darwinian evolution model which provides insight into biological consequences of coherent states populating human genes, including inherited (CAG)(n) repeat tracts.

Authors+Show Affiliations

International Physics Health & Energy, Inc., 5109 82nd Street Suite 7, Lubbock, Texas 79424, USA. cooperwg@sbcglobal.net

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21541839

Citation

Cooper, W Grant. "The Molecular Clock in Terms of Quantum Information Processing of Coherent States, Entanglement and Replication of Evolutionarily Selected Decohered Isomers." Interdisciplinary Sciences, Computational Life Sciences, vol. 3, no. 2, 2011, pp. 91-109.
Cooper WG. The molecular clock in terms of quantum information processing of coherent states, entanglement and replication of evolutionarily selected decohered isomers. Interdiscip Sci. 2011;3(2):91-109.
Cooper, W. G. (2011). The molecular clock in terms of quantum information processing of coherent states, entanglement and replication of evolutionarily selected decohered isomers. Interdisciplinary Sciences, Computational Life Sciences, 3(2), 91-109. https://doi.org/10.1007/s12539-011-0065-x
Cooper WG. The Molecular Clock in Terms of Quantum Information Processing of Coherent States, Entanglement and Replication of Evolutionarily Selected Decohered Isomers. Interdiscip Sci. 2011;3(2):91-109. PubMed PMID: 21541839.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The molecular clock in terms of quantum information processing of coherent states, entanglement and replication of evolutionarily selected decohered isomers. A1 - Cooper,W Grant, Y1 - 2011/05/04/ PY - 2009/12/21/received PY - 2010/07/06/accepted PY - 2010/07/04/revised PY - 2011/5/5/entrez PY - 2011/5/5/pubmed PY - 2012/4/10/medline SP - 91 EP - 109 JF - Interdisciplinary sciences, computational life sciences JO - Interdiscip Sci VL - 3 IS - 2 N2 - Evolutionary pressures have selected quantum uncertainty limits -ΔxΔp (x) ≥ 1/2ħ-to operate on metastable amino DNA protons. This introduces a probability of molecular clock arrangement, keto-amino → enol-imine, where product protons are entangled and participate in coupled quantum oscillation at frequencies of ∼ 10(13) s(-1). The ket "seen by" the transcriptase, reading a coherent enol-imine G'-state, is |φ >= α| + + > +β|+- > +γ|-+ > +δ|-->. The transcriptase implements its measurement and generates an output qubit of observable genetic specificity information in an interval Δt ≪ 10(-13) s. These quantum measurements can specify the relative distribution of coherent G'-C' states at time of measurement. The ensuing quantum entanglement between coherent protons and transcriptase units is utilized as a resource to generate proper decoherence and introduce selected time-dependent substitutions, ts, and deletions, td. Topal-Fresco ts are G'202 → T, G'002 → C, *G020(0) → A and *C202(2) → T, whereas td are exhibited at coherent *A-*T sites. Variation in clock 'tic-rate' is a consequence of clock introduction of initiation codons - UUG, CUG, AUG, GUG - and stop codons, UAA, UAG, UGA. Using approximate quantum methods for times t < ∼ 100 y, the probability, P(t), of keto-amino → enolimine arrangement is P (ρ)(t) = 1/2(γ (ρ)/ħ)(2) t (2) where γ (ρ) is the energy shift. This introduces a quantum Darwinian evolution model which provides insight into biological consequences of coherent states populating human genes, including inherited (CAG)(n) repeat tracts. SN - 1867-1462 UR - https://www.unboundmedicine.com/medline/citation/21541839/The_molecular_clock_in_terms_of_quantum_information_processing_of_coherent_states,_entanglement_and_replication_of_evolutionarily_selected_decohered_isomers L2 - https://dx.doi.org/10.1007/s12539-011-0065-x DB - PRIME DP - Unbound Medicine ER -