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Reduced serum cholesterol with dietary change using fat-modified and oat bran supplemented diets.
J Am Diet Assoc. 1990 Feb; 90(2):223-9.JA

Abstract

A low-fat, low-cholesterol diet and oat bran supplementation for treatment of hypercholesterolemia were studied for their effectiveness in lowering blood lipids and their impact on dietary intake. Seventy-one free-living men and women with hypercholesterolemia (serum cholesterol greater than 75th percentile) were randomly assigned to one of the following four groups: low-fat, low-cholesterol diet (LFLC); low-fat, low-cholesterol diet plus 50 gm/day oat bran (LFLC + OB); 50 gm/day oat bran supplemented diet (OB); or 42.5 gm/day processed oat bran (ready-to-eat cereal containing beta-glucan concentrated from oat bran) (POB). Subjects assigned to regimens OB and POB were requested to add the oat supplement without making additional changes in their diet. Serum cholesterol and high-density lipoprotein cholesterol analyses were performed at 4-week intervals, and diet records were assigned and analyzed. All groups experienced significant decreases in cholesterol from original levels (p less than .05). The average decrease in total serum cholesterol varied from 10% to 17%, with no significant differences among the four groups. High-density lipoprotein cholesterol concentrations decreased in all groups except group 4, in which there was a slight increase; however, no differences were found between groups. Energy, fat, and cholesterol intakes decreased in all groups, suggesting that displacement of higher fat foods from the diet may be one of the many mechanisms whereby oat supplements lower serum cholesterol. In addition, all groups reduced their intakes of calcium, copper, folic acid, and potassium from marginal levels at the beginning of the study.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

Syracuse University, New York 13210.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2154513

Citation

Demark-Wahnefried, W, et al. "Reduced Serum Cholesterol With Dietary Change Using Fat-modified and Oat Bran Supplemented Diets." Journal of the American Dietetic Association, vol. 90, no. 2, 1990, pp. 223-9.
Demark-Wahnefried W, Bowering J, Cohen PS. Reduced serum cholesterol with dietary change using fat-modified and oat bran supplemented diets. J Am Diet Assoc. 1990;90(2):223-9.
Demark-Wahnefried, W., Bowering, J., & Cohen, P. S. (1990). Reduced serum cholesterol with dietary change using fat-modified and oat bran supplemented diets. Journal of the American Dietetic Association, 90(2), 223-9.
Demark-Wahnefried W, Bowering J, Cohen PS. Reduced Serum Cholesterol With Dietary Change Using Fat-modified and Oat Bran Supplemented Diets. J Am Diet Assoc. 1990;90(2):223-9. PubMed PMID: 2154513.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reduced serum cholesterol with dietary change using fat-modified and oat bran supplemented diets. AU - Demark-Wahnefried,W, AU - Bowering,J, AU - Cohen,P S, PY - 1990/2/1/pubmed PY - 1990/2/1/medline PY - 1990/2/1/entrez SP - 223 EP - 9 JF - Journal of the American Dietetic Association JO - J Am Diet Assoc VL - 90 IS - 2 N2 - A low-fat, low-cholesterol diet and oat bran supplementation for treatment of hypercholesterolemia were studied for their effectiveness in lowering blood lipids and their impact on dietary intake. Seventy-one free-living men and women with hypercholesterolemia (serum cholesterol greater than 75th percentile) were randomly assigned to one of the following four groups: low-fat, low-cholesterol diet (LFLC); low-fat, low-cholesterol diet plus 50 gm/day oat bran (LFLC + OB); 50 gm/day oat bran supplemented diet (OB); or 42.5 gm/day processed oat bran (ready-to-eat cereal containing beta-glucan concentrated from oat bran) (POB). Subjects assigned to regimens OB and POB were requested to add the oat supplement without making additional changes in their diet. Serum cholesterol and high-density lipoprotein cholesterol analyses were performed at 4-week intervals, and diet records were assigned and analyzed. All groups experienced significant decreases in cholesterol from original levels (p less than .05). The average decrease in total serum cholesterol varied from 10% to 17%, with no significant differences among the four groups. High-density lipoprotein cholesterol concentrations decreased in all groups except group 4, in which there was a slight increase; however, no differences were found between groups. Energy, fat, and cholesterol intakes decreased in all groups, suggesting that displacement of higher fat foods from the diet may be one of the many mechanisms whereby oat supplements lower serum cholesterol. In addition, all groups reduced their intakes of calcium, copper, folic acid, and potassium from marginal levels at the beginning of the study.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0002-8223 UR - https://www.unboundmedicine.com/medline/citation/2154513/Reduced_serum_cholesterol_with_dietary_change_using_fat_modified_and_oat_bran_supplemented_diets_ L2 - https://medlineplus.gov/cholesterollevelswhatyouneedtoknow.html DB - PRIME DP - Unbound Medicine ER -