TY - JOUR T1 - Analysis of fexofenadine in pharmaceutical formulations using tris(1,10-phenanthroline)-ruthenium(II) peroxydisulphate chemiluminescence system in a multichip device. AU - Al Lawati,Haider A J, AU - Al Dahmani,Zeiyana M, AU - Suliman,Fakhr Eldin O, AU - Al Kindy,Salma M Z, AU - Al-Lawati,Ali M, Y1 - 2011/05/09/ PY - 2010/11/02/received PY - 2011/03/22/revised PY - 2011/03/29/accepted PY - 2011/5/11/entrez PY - 2011/5/11/pubmed PY - 2012/4/14/medline SP - 762 EP - 7 JF - Luminescence : the journal of biological and chemical luminescence JO - Luminescence VL - 26 IS - 6 N2 - A simple, rapid and sensitive method has been developed for the analysis of fexofenadine (FEX) in pharmaceutical formulations, using a tris(1,10-phenanthroline)-ruthenium(II) [Ru(phen)(3)(2+)] peroxydisulphate chemiluminescence (CL) system in a multichip device. Various parameters that influence the CL signal intensity were optimized. These included pH, flow rates and concentration of reagents used. Under optimum conditions, a linear calibration curve in the range 0.05-5.0 µg/mL was obtained. The detection limit was found to be 0.001 µg/mL. The procedure was applied to the analysis of FEX in pharmaceutical products and was found to be free from interference from concomitants usually present in these preparations. SN - 1522-7243 UR - https://www.unboundmedicine.com/medline/citation/21557451/Analysis_of_fexofenadine_in_pharmaceutical_formulations_using_tris_110_phenanthroline__ruthenium_II__peroxydisulphate_chemiluminescence_system_in_a_multichip_device_ L2 - https://doi.org/10.1002/bio.1310 DB - PRIME DP - Unbound Medicine ER -