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Dietary patterns and colorectal cancer: a case-control study from Portugal.
Eur J Cancer Prev 2011; 20(5):389-95EJ

Abstract

Dietary pattern analysis is a powerful technique to study the relationships between diet and cancer, accounting for the specificities of overall dietary intake in each setting. The objective of this study was to quantify the association between dietary patterns and colon and rectum cancers. We evaluated 151 rectum and 102 colon cancer cases selected among surgical patients at the Portuguese Oncology Institute, and 879 community controls. Dietary intake was assessed using a validated food frequency questionnaire. Dietary patterns were defined with principal components and cluster analyses. Age, sex, education, total energy intake, and physical activity-adjusted odds ratios (OR) and 95% confidence intervals (95% CIs) were computed. Three dietary patterns were identified: (i) PI: 'healthy,' high consumption of dairy products, wholegrain cereals, vegetables/salads, legumes, fruits and vegetable soup, and low intake of wine; (ii) PII: 'low consumption of milk and foods containing dietary fiber,' low intake of dairy products, vegetables/salads, legumes, and fruits; and (iii) PIII: 'western,' high consumption of red/processed meat, refined cereals, sugar and sweets, potatoes, alcoholic beverages, and low intake of wholegrain cereals and vegetable soup. Compared with PI, the risk of colon cancer was higher among subjects with PII (OR = 2.07; 95% CI: 1.04-4.14) and PIII (OR = 2.35; 95% CI: 1.19-4.64). The OR estimates for rectum cancer were 3.12 (95% CI: 1.74-5.61) and 1.41 (95% CI: 0.75-2.63), respectively. Our results confirm the higher risk of colorectal cancer among subjects with 'western' diets and 'low consumption of milk and foods containing foods containing dietary fiber'. At a local level, these results support public health messages based on the accumulated evidence on the relationship between individual food items/groups and colorectal cancer.

Authors+Show Affiliations

Department of Oncologic Surgery, Portuguese Oncology Institute--Porto (IPO-Porto), Portugal.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21558858

Citation

Magalhães, Bruno, et al. "Dietary Patterns and Colorectal Cancer: a Case-control Study From Portugal." European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), vol. 20, no. 5, 2011, pp. 389-95.
Magalhães B, Bastos J, Lunet N. Dietary patterns and colorectal cancer: a case-control study from Portugal. Eur J Cancer Prev. 2011;20(5):389-95.
Magalhães, B., Bastos, J., & Lunet, N. (2011). Dietary patterns and colorectal cancer: a case-control study from Portugal. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), 20(5), pp. 389-95. doi:10.1097/CEJ.0b013e328347220a.
Magalhães B, Bastos J, Lunet N. Dietary Patterns and Colorectal Cancer: a Case-control Study From Portugal. Eur J Cancer Prev. 2011;20(5):389-95. PubMed PMID: 21558858.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary patterns and colorectal cancer: a case-control study from Portugal. AU - Magalhães,Bruno, AU - Bastos,Joana, AU - Lunet,Nuno, PY - 2011/5/12/entrez PY - 2011/5/12/pubmed PY - 2011/12/13/medline SP - 389 EP - 95 JF - European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) JO - Eur. J. Cancer Prev. VL - 20 IS - 5 N2 - Dietary pattern analysis is a powerful technique to study the relationships between diet and cancer, accounting for the specificities of overall dietary intake in each setting. The objective of this study was to quantify the association between dietary patterns and colon and rectum cancers. We evaluated 151 rectum and 102 colon cancer cases selected among surgical patients at the Portuguese Oncology Institute, and 879 community controls. Dietary intake was assessed using a validated food frequency questionnaire. Dietary patterns were defined with principal components and cluster analyses. Age, sex, education, total energy intake, and physical activity-adjusted odds ratios (OR) and 95% confidence intervals (95% CIs) were computed. Three dietary patterns were identified: (i) PI: 'healthy,' high consumption of dairy products, wholegrain cereals, vegetables/salads, legumes, fruits and vegetable soup, and low intake of wine; (ii) PII: 'low consumption of milk and foods containing dietary fiber,' low intake of dairy products, vegetables/salads, legumes, and fruits; and (iii) PIII: 'western,' high consumption of red/processed meat, refined cereals, sugar and sweets, potatoes, alcoholic beverages, and low intake of wholegrain cereals and vegetable soup. Compared with PI, the risk of colon cancer was higher among subjects with PII (OR = 2.07; 95% CI: 1.04-4.14) and PIII (OR = 2.35; 95% CI: 1.19-4.64). The OR estimates for rectum cancer were 3.12 (95% CI: 1.74-5.61) and 1.41 (95% CI: 0.75-2.63), respectively. Our results confirm the higher risk of colorectal cancer among subjects with 'western' diets and 'low consumption of milk and foods containing foods containing dietary fiber'. At a local level, these results support public health messages based on the accumulated evidence on the relationship between individual food items/groups and colorectal cancer. SN - 1473-5709 UR - https://www.unboundmedicine.com/medline/citation/21558858/Dietary_patterns_and_colorectal_cancer:_a_case_control_study_from_Portugal_ L2 - http://dx.doi.org/10.1097/CEJ.0b013e328347220a DB - PRIME DP - Unbound Medicine ER -