Tags

Type your tag names separated by a space and hit enter

Validity of the PHQ-2 for the screening of major depression in Parkinson's disease: two questions and one important answer.
Aging Ment Health. 2011 Sep; 15(7):838-43.AM

Abstract

INTRODUCTION

Depression is the most common psychiatric comorbidity in Parkinson's disease (PD), but is often under-diagnosed and under-recognized.

OBJECTIVES

To evaluate and compare the psychometric qualities of the Patient Health Questionnaire (PHQ-2) and the depression item of the Unified Parkinson's Disease Rating Scale (UPDRS).

METHOD

Cross-sectional study conducted at a movement disorders outpatient clinic. One hundred ten patients with a diagnosis of PD without dementia were evaluated. A neurologist administered the PHQ-2 and the UPDRS, and the diagnosis of major depression was performed using the structured clinical interview for DSM disorders - clinical version. Two self-rating scales (Zung Self-rating Depression Scale and 15-item Geriatric Depression Scale) were also used.

RESULTS

The prevalence of current depression in the sample was 25.5% (n = 28). The scores of the PHQ-2 discriminated between subjects with and without depression, with an area under the receiver operating characteristic curve of 0.90. The sensitivity and specificity for a cut-off score of three were 75% and 89%, respectively. The values for the depression item of the UPDRS were slightly lower.

CONCLUSION

The PHQ-2 is a valid tool for screening depression in PD.

Authors+Show Affiliations

Department of Neuroscience and Behavior of the Ribeirão Preto Medical School, University of São Paulo, INCT Translational Medicine, Brazil. setroh@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Validation Study

Language

eng

PubMed ID

21562987

Citation

Chagas, Marcos H N., et al. "Validity of the PHQ-2 for the Screening of Major Depression in Parkinson's Disease: Two Questions and One Important Answer." Aging & Mental Health, vol. 15, no. 7, 2011, pp. 838-43.
Chagas MH, Crippa JA, Loureiro SR, et al. Validity of the PHQ-2 for the screening of major depression in Parkinson's disease: two questions and one important answer. Aging Ment Health. 2011;15(7):838-43.
Chagas, M. H., Crippa, J. A., Loureiro, S. R., Hallak, J. E., Meneses-Gaya, C. d., Machado-de-Sousa, J. P., Rodrigues, G. R., Filho, A. S., Sanches, R. F., & Tumas, V. (2011). Validity of the PHQ-2 for the screening of major depression in Parkinson's disease: two questions and one important answer. Aging & Mental Health, 15(7), 838-43. https://doi.org/10.1080/13607863.2011.569482
Chagas MH, et al. Validity of the PHQ-2 for the Screening of Major Depression in Parkinson's Disease: Two Questions and One Important Answer. Aging Ment Health. 2011;15(7):838-43. PubMed PMID: 21562987.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Validity of the PHQ-2 for the screening of major depression in Parkinson's disease: two questions and one important answer. AU - Chagas,Marcos H N, AU - Crippa,José A S, AU - Loureiro,Sonia R, AU - Hallak,Jaime E C, AU - Meneses-Gaya,Carolina de, AU - Machado-de-Sousa,João P, AU - Rodrigues,Guilherme R, AU - Filho,Alaor S, AU - Sanches,Rafael F, AU - Tumas,Vitor, Y1 - 2011/05/23/ PY - 2011/5/13/entrez PY - 2011/5/13/pubmed PY - 2011/11/10/medline SP - 838 EP - 43 JF - Aging & mental health JO - Aging Ment Health VL - 15 IS - 7 N2 - INTRODUCTION: Depression is the most common psychiatric comorbidity in Parkinson's disease (PD), but is often under-diagnosed and under-recognized. OBJECTIVES: To evaluate and compare the psychometric qualities of the Patient Health Questionnaire (PHQ-2) and the depression item of the Unified Parkinson's Disease Rating Scale (UPDRS). METHOD: Cross-sectional study conducted at a movement disorders outpatient clinic. One hundred ten patients with a diagnosis of PD without dementia were evaluated. A neurologist administered the PHQ-2 and the UPDRS, and the diagnosis of major depression was performed using the structured clinical interview for DSM disorders - clinical version. Two self-rating scales (Zung Self-rating Depression Scale and 15-item Geriatric Depression Scale) were also used. RESULTS: The prevalence of current depression in the sample was 25.5% (n = 28). The scores of the PHQ-2 discriminated between subjects with and without depression, with an area under the receiver operating characteristic curve of 0.90. The sensitivity and specificity for a cut-off score of three were 75% and 89%, respectively. The values for the depression item of the UPDRS were slightly lower. CONCLUSION: The PHQ-2 is a valid tool for screening depression in PD. SN - 1364-6915 UR - https://www.unboundmedicine.com/medline/citation/21562987/Validity_of_the_PHQ_2_for_the_screening_of_major_depression_in_Parkinson's_disease:_two_questions_and_one_important_answer_ L2 - http://www.tandfonline.com/doi/full/10.1080/13607863.2011.569482 DB - PRIME DP - Unbound Medicine ER -