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Acute kidney injury in intensive care unit: incidence, risk factors and mortality rate.
Saudi J Kidney Dis Transpl. 2011 May; 22(3):464-70.SJ

Abstract

Acute kidney injury (AKI) is a risk factor for increased mortality in critically ill patients. To assess the incidence, risk factors and outcome of patients who develop AKI in the intensive care units (ICUs), we retrospectively studied 235 patients admitted to the ICU of Shahid Mohamadi Hospital, Hormozgan, Iran, and compared those who developed AKI and those who did not. There were 31.1% of patients who developed AKI during ICU admission. There was a significant difference in the mean age, serum sodium (Na), potassium (K), urea, blood urea nitrogen (BUN) and creatinine (Cr) levels and also platelets, on admission, between patients with and without AKI. Acute physiology and chronic health evaluation (APACHE) II score on admission was significantly higher in AKI patients and Glasgow coma scale (GCS) was significantly lower. The mortality of AKI patients (72.6%) was significantly higher than non-AKI patients (25.91%). The number of underlying diseases and GCS and APACHE II score on admission were significantly different between the expired and survived patients. We conclude that age, first serum K level and APACHE II score on admission time were powerful independent predictors of developing AKI in ICU patients. The GCS on admission and the presence of two or more underlying diseases accurately predict the mortality in AKI positive ICU patients.

Authors+Show Affiliations

Department of Nephrology, Hormozgan University of Medical Sciences and Health Services, Hormozgan, Iran. swt_f@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21566301

Citation

Samimagham, Hamid Reza, et al. "Acute Kidney Injury in Intensive Care Unit: Incidence, Risk Factors and Mortality Rate." Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia, vol. 22, no. 3, 2011, pp. 464-70.
Samimagham HR, Kheirkhah S, Haghighi A, et al. Acute kidney injury in intensive care unit: incidence, risk factors and mortality rate. Saudi J Kidney Dis Transpl. 2011;22(3):464-70.
Samimagham, H. R., Kheirkhah, S., Haghighi, A., & Najmi, Z. (2011). Acute kidney injury in intensive care unit: incidence, risk factors and mortality rate. Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 22(3), 464-70.
Samimagham HR, et al. Acute Kidney Injury in Intensive Care Unit: Incidence, Risk Factors and Mortality Rate. Saudi J Kidney Dis Transpl. 2011;22(3):464-70. PubMed PMID: 21566301.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute kidney injury in intensive care unit: incidence, risk factors and mortality rate. AU - Samimagham,Hamid Reza, AU - Kheirkhah,Soudabeh, AU - Haghighi,Anousheh, AU - Najmi,Zahra, PY - 2011/5/14/entrez PY - 2011/5/14/pubmed PY - 2011/8/6/medline SP - 464 EP - 70 JF - Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia JO - Saudi J Kidney Dis Transpl VL - 22 IS - 3 N2 - Acute kidney injury (AKI) is a risk factor for increased mortality in critically ill patients. To assess the incidence, risk factors and outcome of patients who develop AKI in the intensive care units (ICUs), we retrospectively studied 235 patients admitted to the ICU of Shahid Mohamadi Hospital, Hormozgan, Iran, and compared those who developed AKI and those who did not. There were 31.1% of patients who developed AKI during ICU admission. There was a significant difference in the mean age, serum sodium (Na), potassium (K), urea, blood urea nitrogen (BUN) and creatinine (Cr) levels and also platelets, on admission, between patients with and without AKI. Acute physiology and chronic health evaluation (APACHE) II score on admission was significantly higher in AKI patients and Glasgow coma scale (GCS) was significantly lower. The mortality of AKI patients (72.6%) was significantly higher than non-AKI patients (25.91%). The number of underlying diseases and GCS and APACHE II score on admission were significantly different between the expired and survived patients. We conclude that age, first serum K level and APACHE II score on admission time were powerful independent predictors of developing AKI in ICU patients. The GCS on admission and the presence of two or more underlying diseases accurately predict the mortality in AKI positive ICU patients. SN - 1319-2442 UR - https://www.unboundmedicine.com/medline/citation/21566301/Acute_kidney_injury_in_intensive_care_unit:_incidence_risk_factors_and_mortality_rate_ L2 - http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=3;spage=464;epage=470;aulast=Samimagham DB - PRIME DP - Unbound Medicine ER -