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[Preliminary study on the value of ratio of serum luteinizing hormone/follicle-stimulating hormone in diagnosis of polycystic ovarian syndrome among women with polycystic ovary].
Zhonghua Fu Chan Ke Za Zhi. 2011 Mar; 46(3):177-80.ZF

Abstract

OBJECTIVE

To investigate the value of ratio of luteinizing hormone (LH) to follicle-stimulating hormone (FSH) in diagnosis of polycystic ovarian syndrome (PCOS) among women with polycystic ovary (PCO) and to compare the difference of the diagnostic criteria between the Rotterdam Consensus and the Committee for Reproductive and Endocrine in Japan Society of Obstetrics and Gynecology.

METHODS

By means of transvaginal Doppler ultrasound, 195 women with PCO were diagnosed in Nanfang Hospital of Reproductive Medicine Center and compare difference of multiple clinical indexes according to Rotterdam consensus and Japan consensus respectively. In the mean time, the ratio of LH/FSH, the level of LH, testosterone (T) and recevier operating characteristic (ROC) curve were explored to on the value of diagnosis of PCOS.

RESULTS

By Rotterdam consensus, 144 women were diagnosed with PCOS and 51 women were non-PCOS, while 111 were identified as PCOS and 84 were non-PCOS according to Japan consensus. LH/FSH in PCOS and non-PCOS were 1.59 ± 0.84 and 0.85 ± 0.47 respectively when based on Rotterdam consensus, and this ratio were 1.87 ± 0.76 in PCOS and 0.78 ± 0.39 in non-PCOS based on Japan consensus. When using LH/FSH to diagnosis PCOS by Rotterdam consensus and Japan consensus, areas under ROC curve are 0.786 and 0.942, respectively.

CONCLUSIONS

The ratio of LH/FSH ≥ 1 provide the significant value in the diagnosis of PCOS. The criteria of the Committee for Reproductive and Endocrine in Japan Society of Obstetrics and Gynecology is more suitable for Chinese patients.

Authors+Show Affiliations

Reproductive Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

chi

PubMed ID

21575449

Citation

Ma, Cong-shun, et al. "[Preliminary Study On the Value of Ratio of Serum Luteinizing Hormone/follicle-stimulating Hormone in Diagnosis of Polycystic Ovarian Syndrome Among Women With Polycystic Ovary]." Zhonghua Fu Chan Ke Za Zhi, vol. 46, no. 3, 2011, pp. 177-80.
Ma CS, Lin Y, Zhang CH, et al. [Preliminary study on the value of ratio of serum luteinizing hormone/follicle-stimulating hormone in diagnosis of polycystic ovarian syndrome among women with polycystic ovary]. Zhonghua Fu Chan Ke Za Zhi. 2011;46(3):177-80.
Ma, C. S., Lin, Y., Zhang, C. H., Xu, H., Li, Y. F., Zhang, S. C., Tan, Y., Quan, S., & Xing, F. Q. (2011). [Preliminary study on the value of ratio of serum luteinizing hormone/follicle-stimulating hormone in diagnosis of polycystic ovarian syndrome among women with polycystic ovary]. Zhonghua Fu Chan Ke Za Zhi, 46(3), 177-80.
Ma CS, et al. [Preliminary Study On the Value of Ratio of Serum Luteinizing Hormone/follicle-stimulating Hormone in Diagnosis of Polycystic Ovarian Syndrome Among Women With Polycystic Ovary]. Zhonghua Fu Chan Ke Za Zhi. 2011;46(3):177-80. PubMed PMID: 21575449.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Preliminary study on the value of ratio of serum luteinizing hormone/follicle-stimulating hormone in diagnosis of polycystic ovarian syndrome among women with polycystic ovary]. AU - Ma,Cong-shun, AU - Lin,Yun, AU - Zhang,Chun-hui, AU - Xu,Hong, AU - Li,Ya-fang, AU - Zhang,Shu-chen, AU - Tan,Yan, AU - Quan,Song, AU - Xing,Fu-qi, PY - 2011/5/18/entrez PY - 2011/5/18/pubmed PY - 2012/5/25/medline SP - 177 EP - 80 JF - Zhonghua fu chan ke za zhi JO - Zhonghua Fu Chan Ke Za Zhi VL - 46 IS - 3 N2 - OBJECTIVE: To investigate the value of ratio of luteinizing hormone (LH) to follicle-stimulating hormone (FSH) in diagnosis of polycystic ovarian syndrome (PCOS) among women with polycystic ovary (PCO) and to compare the difference of the diagnostic criteria between the Rotterdam Consensus and the Committee for Reproductive and Endocrine in Japan Society of Obstetrics and Gynecology. METHODS: By means of transvaginal Doppler ultrasound, 195 women with PCO were diagnosed in Nanfang Hospital of Reproductive Medicine Center and compare difference of multiple clinical indexes according to Rotterdam consensus and Japan consensus respectively. In the mean time, the ratio of LH/FSH, the level of LH, testosterone (T) and recevier operating characteristic (ROC) curve were explored to on the value of diagnosis of PCOS. RESULTS: By Rotterdam consensus, 144 women were diagnosed with PCOS and 51 women were non-PCOS, while 111 were identified as PCOS and 84 were non-PCOS according to Japan consensus. LH/FSH in PCOS and non-PCOS were 1.59 ± 0.84 and 0.85 ± 0.47 respectively when based on Rotterdam consensus, and this ratio were 1.87 ± 0.76 in PCOS and 0.78 ± 0.39 in non-PCOS based on Japan consensus. When using LH/FSH to diagnosis PCOS by Rotterdam consensus and Japan consensus, areas under ROC curve are 0.786 and 0.942, respectively. CONCLUSIONS: The ratio of LH/FSH ≥ 1 provide the significant value in the diagnosis of PCOS. The criteria of the Committee for Reproductive and Endocrine in Japan Society of Obstetrics and Gynecology is more suitable for Chinese patients. SN - 0529-567X UR - https://www.unboundmedicine.com/medline/citation/21575449/[Preliminary_study_on_the_value_of_ratio_of_serum_luteinizing_hormone/follicle_stimulating_hormone_in_diagnosis_of_polycystic_ovarian_syndrome_among_women_with_polycystic_ovary]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&issn=0529-567X&year=2011&vol=46&issue=3&fpage=177 DB - PRIME DP - Unbound Medicine ER -