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Cutaneous leishmaniasis. Treatment with combined cryotherapy and intralesional stibogluconate injection.
Int J Dermatol. 1990 Jan-Feb; 29(1):56-9.IJ

Abstract

A combination of both intralesional stibogluconate injection and superficial cryotherapy (not including the base of the lesion nor the 1-2 mm rim of the surrounding normal skin) was performed in an attempt to improve the therapeutic efficacy of either of the two modalities when used separately in the treatment of cutaneous leishmaniasis. This combined therapy resulted in a 100% cure rate in 15 patients with 23 lesions of cutaneous leishmaniasis. Two control groups, one treated with superficial cryo and the other treated with intralesional stibogluconate injection alone were included in the study for evaluation. The results obtained by combined superficial freezing and intralesional stibogluconate injection were much more impressive than those obtained by each of the two modalities when used alone.

Authors+Show Affiliations

Department of Dermatology, Rashid Hospital, Dubai, United Arab Emirates.No affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

2158487

Citation

el Darouti, M A., and S M. al Rubaie. "Cutaneous Leishmaniasis. Treatment With Combined Cryotherapy and Intralesional Stibogluconate Injection." International Journal of Dermatology, vol. 29, no. 1, 1990, pp. 56-9.
el Darouti MA, al Rubaie SM. Cutaneous leishmaniasis. Treatment with combined cryotherapy and intralesional stibogluconate injection. Int J Dermatol. 1990;29(1):56-9.
el Darouti, M. A., & al Rubaie, S. M. (1990). Cutaneous leishmaniasis. Treatment with combined cryotherapy and intralesional stibogluconate injection. International Journal of Dermatology, 29(1), 56-9.
el Darouti MA, al Rubaie SM. Cutaneous Leishmaniasis. Treatment With Combined Cryotherapy and Intralesional Stibogluconate Injection. Int J Dermatol. 1990 Jan-Feb;29(1):56-9. PubMed PMID: 2158487.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cutaneous leishmaniasis. Treatment with combined cryotherapy and intralesional stibogluconate injection. AU - el Darouti,M A, AU - al Rubaie,S M, PY - 1990/1/1/pubmed PY - 1990/1/1/medline PY - 1990/1/1/entrez SP - 56 EP - 9 JF - International journal of dermatology JO - Int J Dermatol VL - 29 IS - 1 N2 - A combination of both intralesional stibogluconate injection and superficial cryotherapy (not including the base of the lesion nor the 1-2 mm rim of the surrounding normal skin) was performed in an attempt to improve the therapeutic efficacy of either of the two modalities when used separately in the treatment of cutaneous leishmaniasis. This combined therapy resulted in a 100% cure rate in 15 patients with 23 lesions of cutaneous leishmaniasis. Two control groups, one treated with superficial cryo and the other treated with intralesional stibogluconate injection alone were included in the study for evaluation. The results obtained by combined superficial freezing and intralesional stibogluconate injection were much more impressive than those obtained by each of the two modalities when used alone. SN - 0011-9059 UR - https://www.unboundmedicine.com/medline/citation/2158487/Cutaneous_leishmaniasis__Treatment_with_combined_cryotherapy_and_intralesional_stibogluconate_injection_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0011-9059&date=1990&volume=29&issue=1&spage=56 DB - PRIME DP - Unbound Medicine ER -